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Effects of topically administered neuroprotective drugs in early stages of diabetic retinopathy: Results of the EUROCONDOR clinical trial

Autor: Simo, Rafael, Hernandez, Cristina, Porta, Massimo, Bandello, Francesco, Grauslund, Jakob, Harding, Simon P, Aldington, Stephen J, Egan, Catherine, Frydkjaer-Olsen, Ulrik, Garcia-Arumi, Jose, Gibson, Jonathan, Lang, Gabriele E, Lattanzio, Rosangela, Massin, Pascale, Midena, Edoardo, Ponsati, Berta, Ribeiro, Luisa, Scanlon, Peter, Lobo, Conceicao, Costa, Miguel Angelo, Cunha-Vaz, Jose, Garcia-Ramirez, M, van Reck, E, Gil, E, Morillas, M, Cunha-Vaz, J, Ribeiro, L, Lobo, C, Costa, MA, Nunes, S, Figueira, J, Pereira-Marques, I, Neves, C, Schwartz, C, Porta, M, Trento, M, Durando, O, Merlo, S, Bandello, F, Lattanzio, R, Zucchiatti, I, Grauslund, J, Frydkjaer-Olsen, U, Harding, SP, Scanlon, P, Aldington, SJ, Jones, V, Johnson, L, Carter, S, Spurway, J, Egan, C, Esposti, S, Leitch-Devlin, L, Rocco, V, Rees, A, Garcia-Arumi, J, Zapata, MA, Boixadera, A, Macia, C, Distefano, L, Torrent, T, Casals, F, de Dios, N, Gibson, J, Lang, GE, Jens-Ulrich, W, Christian, E, Adnan, K, Massin, P, Erginay, A, Midena, E, Vujosevic, S, Pilotto, E, Longhin, E, Convento, E, Ponsati, B, Fernandez-Carneado, J, Arrastia-Casado, S, Orgue, S, Ramirez-Lamelas, DT, Almazan-Moga, A, Salva, A, Riera, L, Treatme, European Consortium Early

Publikováno v: Simó, R, Hernández, C, Porta, M, Bandello, F, Grauslund, J, Harding, S P, Aldington, S J, Egan, C, Frydkjaer-Olsen, U, García-Arumí, J, Gibson, J, Lang, G E, Lattanzio, R, Massin, P, Midena, E, Ponsati, B, Ribeiro, L, Scanlon, P, Lobo, C, Costa, M Â, Cunha-Vaz, J & European Consortium for the Early Treatment of Diabetic Retinopathy (EUROCONDOR) 2019, ' Effects of Topically Administered Neuroprotective Drugs in Early Stages of Diabetic Retinopathy. Results of the EUROCONDOR Clinical Trial ', Diabetes, vol. 68, no. 2, pp. 457-463 . https://doi.org/10.2337/db18-0682
DIABETES

The primary objective of this study was to assess whether the topical administration of two neuroprotective drugs (brimonidine and somatostatin) could prevent or arrest retinal neurodysfunction in patients with type 2 diabetes. For this purpose, adul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1575fdf8833bf6dfe56383306a0025af

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Feature visualisation of classification of diabetic retinopathy using a convolutional neural network

Autor: Pratt, H, Coenen, F, Harding, SP, Broadbent, DM, Zheng, Y

Publikováno v: CEUR Workshop Proceedings

Convolutional Neural Networks (CNNs) have been demonstrated to achieve state-of-the-art results on complex computer vision tasks, including medical image diagnosis of Diabetic Retinopathy (DR). CNNs are powerful because they determine relevant image

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::139f4e3c32bd7126d452b1697b6c96fc
http://livrepository.liverpool.ac.uk/3054853/1/kdh-2019_Pratt_Paper_10.pdf

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Intralesional macular atrophy in antiVEGF therapy for age-related macular degeneration in the IVAN trial

Autor: Harding, SP, Bailey, Clare, Scott, Lauren, Rogers, Chris, Reeves, Barnaby, Hamill, Barbra, Peto, Tunde, Chakravarthy, Usha

Publikováno v: Ophthalmology

Purpose To report on the development and progression of macular atrophy (MA) and its relationship with morphologic and functional measures in study and fellow eyes in the Inhibition of vascular endothelial growth factor (VEGF) in Age-related Choroida

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::2ad45febd38fd0da0e4f9b1a73806907
http://livrepository.liverpool.ac.uk/3025592/1/BaileyEtAl_Ophthalmology2018.docx

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Ranibizumab versus bevacizumab to treat neovascular age-related macular degeneration: One-year findings from the IVAN randomized trial

Autor: Chakravarthy, U, Harding, SP, Rogers, CA, Downes, SM, Lotery, AJ, Wordsworth, S, Reeves, BC

Purpose: To compare the efficacy and safety of ranibizumab and bevacizumab intravitreal injections to treat neovascular age-related macular degeneration (nAMD). Design: Multicenter, noninferiority factorial trial with equal allocation to groups. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::56c9ca143274bd492bb66789e8a67ee7
https://ora.ox.ac.uk/objects/uuid:deeb8888-f901-4a95-a78e-1dcc2acf732b

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