Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Hardik H Amin"'
Autor:
Nilesh M. Meghani, Beom-Jin Lee, Hardik H. Amin, Saraswathy Nagendran, Behzad Nili-Ahmadabadi
Publikováno v:
Infectious Disorders - Drug Targets. 20:598-610
For a number of decades, schistosomiasis has remained a public threat and an economic burden in a number of countries, directly impacting over 200 million people. The past 15 years have seen tremendous progress in the development of high-throughput m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3207199810352dfe96db1e167f0add5
https://doi.org/10.2174/1871526519666191015170536
https://doi.org/10.2174/1871526519666191015170536
Autor:
Phuong H.L. Tran, Hardik H. Amin, Thao T.D. Tran, Chulhun Park, Beom-Jin Lee, Van Hanh Nguyen, Nilesh M. Meghani
Publikováno v:
International Journal of Pharmaceutics. 564:124-135
The aim of this study was to investigate the impact of different chain length fatty acids on physicochemical properties and cancer targeting of fattigation-platform nanoparticles (NPs). Two different types of fatty acids (short chain, 2-hydroxybutyri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3d6a5cdb14e9c47d13e8b79cf54a48
https://doi.org/10.1016/j.ijpharm.2019.04.038
https://doi.org/10.1016/j.ijpharm.2019.04.038
Autor:
Stephanie K Lathrop, Hardik H Amin, Clara J Davison, Haley A Partlow, Elizabeth K Lorentz, David J Burkhart, Jay T Evans
Publikováno v:
The Journal of Immunology. 208:65.32-65.32
Subunit vaccines require an adjuvant, as protein antigens alone provoke a very poor immune response. Liposomes can be used to deliver an adjuvant, particularly when it is an amphipathic molecule such as a toll-like receptor (TLR) 4 agonist. TLR4 enga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2258e488506d4afe6b777e0a0da85f0f
https://doi.org/10.4049/jimmunol.208.supp.65.32
https://doi.org/10.4049/jimmunol.208.supp.65.32
Autor:
Hardik H. Amin, Chulhun Park, Phuong H.L. Tran, Thao T.D. Tran, Beom-Jin Lee, Nilesh M. Meghani, Van Hong Nguyen
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 170:179-186
Albumin is the most abundant protein in blood, and is the most frequently identified protein in the protein corona of nanoparticles (NPs). Thus, albumin plays an important role in modulating NPs' physicochemical properties and bioavailability. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b461165cd87645ae5eaf5ff8ec96a8
https://doi.org/10.1016/j.colsurfb.2018.05.060
https://doi.org/10.1016/j.colsurfb.2018.05.060
Autor:
Beom-Jin Lee, Euichaul Oh, Qing-Ri Cao, Zhong Zhu Piao, Phuong H.L. Tran, Thao T.D. Tran, Jun-Bom Park, Hardik H. Amin, Nilesh M. Meghani, Jing-Hao Cui, Chulhun Park
Publikováno v:
Journal of Drug Delivery Science and Technology. 46:365-377
The aims of this work were to design pH-independent controlled release (CR) tablet containing nanonizing solid dispersion (SD) adsorbed on hydrophilic silica (Aeroperl® 300/30). Valsartan (VAL) was chosen to simultaneously modulate solubility and re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::624bb30e5e1d0017bd857b7376f3b920
https://doi.org/10.1016/j.jddst.2018.05.031
https://doi.org/10.1016/j.jddst.2018.05.031
Autor:
Beom-Jin Lee, Jun-Bom Park, Qing-Ri Cao, Hardik H. Amin, Nilesh M. Meghani, Jing-Hao Cui, Chulhun Park
Publikováno v:
International Journal of Pharmaceutics. 545:101-112
The principles of bioorthogonal click chemistry and metabolic glycoengineering were applied to produce targeted anti-cancer drug delivery via fattigation-platform-based gelatin-oleic nanoparticles. A sialic acid precursor (Ac4ManNAz) was introduced t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e273d6703c8fb88cc246e4a49e27f6a
https://doi.org/10.1016/j.ijpharm.2018.04.047
https://doi.org/10.1016/j.ijpharm.2018.04.047
Publikováno v:
Drug Discovery Today. 22:1604-1619
The concept of click chemistry (CC), first introduced by K.B. Sharpless, has been widely adopted for use in drug discovery, novel drug delivery systems (DDS), polymer chemistry, and material sciences. In this review, we outline novel aspects of CC re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea9a85bb610f9aa211e5903b396ef38
https://doi.org/10.1016/j.drudis.2017.07.007
https://doi.org/10.1016/j.drudis.2017.07.007
Autor:
Beom-Jin Lee, Phuong H.L. Tran, Hardik H. Amin, Nilesh M. Meghani, Thao Truong-Dinh Tran, Chulhun Park, Van Hong Nguyen
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 159:571-579
A major hurdle in cancer treatment is the precise targeting of drugs to the cancer site. As many cancer cells overexpress the transferrin receptor (TfR), the transferrin (Tf)-TfR interaction is widely exploited to target cancer cells. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c94d468b0d815c12a19407506a429d
https://doi.org/10.1016/j.colsurfb.2017.08.014
https://doi.org/10.1016/j.colsurfb.2017.08.014
Publikováno v:
Journal of Drug Delivery Science and Technology. 41:222-230
In this study, apotransferrin (Tf)-stearic acid conjugate was newly synthesized via “fattigation method” to form self-assembled nanoparticles (NPs) containing a hydrophobic model drug, paclitaxel (PAC). Then, physicochemical properties and cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0abaa90cb339f124d6ef234abe569b56
https://doi.org/10.1016/j.jddst.2017.07.013
https://doi.org/10.1016/j.jddst.2017.07.013
Publikováno v:
Therapeutic Delivery. 8:775-790
Pharmaceutical dosage forms address diverse key components but satisfying unmet patient needs to enhance patient adherence is a major challenge. The desired design of patient-centered drug products should be based on characteristics of various compon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3dd663e83037756924f2523592df785
https://doi.org/10.4155/tde-2017-0039
https://doi.org/10.4155/tde-2017-0039