Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hardi, Lührs"'
Publikováno v:
Biochemical and Biophysical Research Communications. 254:400-405
Cholecystokinin (CCK) dose-dependently stimulates enzyme secretion or loss of cell integrity in the exocrine pancreas. Signaling mechanims include tyrosine phosphorylation of p125 FAK and paxillin. Here, we examine their potential function. Maximum p
Publikováno v:
Gastroenterology. 115:1254-1262
Background & Aims : In transgenic mice overexpressing transforming growth factor (TGF)-α in the exocrine pancreas, progressive pancreatic fibrosis and a transdifferentiation of acinar cells to duct-like cells occurs. The present study was undertaken
Autor:
Berenike B. M. Flossmann-Kast, Manfred P. Lutz, Markus W. Büchler, Roger Vogelmann, Hardi Lührs, I.B.Silke Eßer, Helmut Friess, Guido Adler
Publikováno v:
Biochemical and Biophysical Research Communications. 243:503-508
Src family tyrosine kinases participate in the regulation of cell adhesion, cell growth and differentiation. Here, we examine for the first time the potential role of Src for growth regulation of human pancreatic carcinoma cells. By immunohistochemic
Autor:
Hardi, Lührs, Theodor, Kudlich, Manfred, Neumann, Jürgen, Schauber, Ralph, Melcher, Andrea, Gostner, Wolfgang, Scheppach, Thomas P, Menzel
Publikováno v:
Anticancer research. 22(3)
Tumor necrosis factor (TNFalpha)-induced apoptosis is limited by concomitant activation of nuclear factor kappa B (NF-kappaB)-dependent anti-apoptotic genes. Butyrate inhibits NF-kappaB activation so that co-treatment with butyrate effectively enhanc
Publikováno v:
Gut. 41(4)
Background—Cancer of the oesophagus has so far eluded every attempt at pharmacological treatment. The recent advent of somatic gene therapy offers a new therapeutic approach to malignant tumours.Aim—To investigate whether and how gene transfer in
Publikováno v:
ResearcherID
BACKGROUND: Patients with severe acute pancreatitis die of complications closely related to the systemic activation of protease cascades. AIM: To examine the effects of human C1 esterase inhibitor (C1 INH) and antithrombin III (AT III) on two experim
Autor:
Michael Beil, Thomas Seufferlein, Guido Adler, Roland M. Schmid, Hardi Lührs, Michael J. Seckl
Publikováno v:
Gastroenterology. 118:A540
Publikováno v:
Gastroenterology. 114:A507