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Long-term blood pressure lowering and cGMP-activating actions of the novel ANP analog MANP.

Autor: Yang Chen, Schaefer, Jacob J., Iyer, Seethalakshmi R., Harders, Gerald E., Shuchong Pan, Sangaralingham, S. Jeson, Chen, Horng H., Redfield, Margaret M., Burnett Jr., John C.

Publikováno v: American Journal of Physiology: Regulatory, Integrative & Comparative Physiology; Apr2020, Vol. 318 Issue 4, pR669-R676, 8p

Acute and Chronic Subcutaneous Administration of ZD100, a Novel pGC-A/cGMP Peptide Activator, Demonstrates Robust Antihypertensive Efficacy in Rodents

Autor: Chen, Yang, Iyer, Seethalakshmi R., Harders, Gerald E., Redfield, Margaret M., Burnett, John C.

Publikováno v: In Journal of Cardiac Failure August 2019 25(8) Supplement:S7-S7

CRRL269: a novel designer and renal-enhancing pGC-A peptide activator.

Autor: Yang Chen, Harty, Gail J., Huntley, Brenda K., Iyer, Seethalakshmi R., Heublein, Denise M., Harders, Gerald E., Meems, Laura, Shuchong Pan, Sangaralingham, S. Jeson, Ichiki, Tomoko, Burnett, Jr., John C.

Publikováno v: American Journal of Physiology: Regulatory, Integrative & Comparative Physiology; Mar2018, Vol. 314 Issue 3, pR407-R414, 8p, 2 Charts, 8 Graphs

Long-Term Cardiac proBNP Gene Delivery Prevents the Development of Hypertensive Heart Disease in Spontaneously Hypertensive Rats

Autor: Cataliotti, Alessandro, Tonne, Jason M., Bellavia, Diego, Martin, Fernando L., Oehler, Elise A., Harders, Gerald E., Campbell, Jarryd M., Peng, Kaw-Whye, Russell, Steve J., Malatino, Lorenzo S., Burnett, John C., Ikeda, Yasuhiro

Diastolic dysfunction associated with high blood pressure (BP) leads to cardiac remodeling and fibrosis and progression to congestive heart failure. B-type natriuretic peptide (BNP) has BP-lowering, antifibrotic, and antihypertrophic properties, whic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1558f72023aeb0cbe02582c801f50204
https://europepmc.org/articles/PMC3081597/