Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hardeep K. Vora"'
Publikováno v:
Journal of Vector Borne Diseases, Vol 43, Iss 2, Pp 43-52 (2006)
Background & objectives: Glycolysis is the sole source of energy for the intraerythrocytic stages ofPlasmodium falciparum, making glycolytic enzymes putative therapeutic targets. Enolase, a singlecopy gene in P. falciparum is one such enzyme whose ac
Externí odkaz:
https://doaj.org/article/3e1d6795ae2c49f883badc5aefcbf152
Autor:
Hardeep K. Vora, Shobhona Sharma, K. Sadagopan, Alfica Sehgal, Gotam K. Jarori, Ipsita Pal-Bhowmick
Publikováno v:
European Journal of Biochemistry. 271:4845-4854
We have cloned, over-expressed and purified enolase from Plasmodium falciparum strain NF54 in Escherichia coli in active form, as an N-terminal His6-tagged protein. The sequence of the cloned enolase from the NF54 strain is identical to that of strai
Publikováno v:
Archives of biochemistry and biophysics. 485(2)
Plasmodium falciparum enolase (Pfen) is of photosynthetic lineage as evident from the presence of a plant like pentapeptide insert (104)EWGWS(108) in a highly conserved surface loop of the protein. Such a unique region which is absent in human enolas
Publikováno v:
Malaria Journal
Malaria Journal, Vol 6, Iss 1, p 45 (2007)
Malaria Journal, Vol 6, Iss 1, p 45 (2007)
Background Enolase (2-Phospho-D-glycerate hydrolase; EC 4.2.1.11) is one of the glycolytic enzymes, whose levels are highly elevated in malaria parasite infected red blood cells. In several organisms, enolases have been shown to have diverse non glyc