Neuroleptic activity in 5-aryltetrahydro-gamma-carbolines

Autor: Willard M. Welch, Harbert Ca, B. K. Koe, Albert Weissman, J. J. Plattner

Publikováno v: Journal of medicinal chemistry. 23(6)

A series of 5-aryltetrahydro-gamma-carbolines was prepared by a novel N-arylation procedure and tested for neuroleptic activity in a rat antiamphetamine model. The systematic exploration of structural parameters leading to 8-fluoro-5-(4-fluorophenyl)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16efd95abd69ec1f1d5ef43d73af7332
https://pubmed.ncbi.nlm.nih.gov/6104732

Infrared skin damage thresholds from 1319-nm continuous-wave laser exposures.

Autor: Oliver JW; 711th Human Performance Wing, Optical Radiation Branch, 4141 Petroleum Road, JBSA Fort Sam Houston, Texas 78234., Vincelette R; TASC Inc., 4241 Woodcock Drive, Suite B-100, San Antonio, Texas 78228., Noojin GD; TASC Inc., 4241 Woodcock Drive, Suite B-100, San Antonio, Texas 78228., Clark CD; TASC Inc., 4241 Woodcock Drive, Suite B-100, San Antonio, Texas 78228., Harbert CA; TASC Inc., 4241 Woodcock Drive, Suite B-100, San Antonio, Texas 78228., Schuster KJ; TASC Inc., 4241 Woodcock Drive, Suite B-100, San Antonio, Texas 78228., Shingledecker AD; TASC Inc., 4241 Woodcock Drive, Suite B-100, San Antonio, Texas 78228., Kumru SS; 711th Human Performance Wing, Optical Radiation Branch, 4141 Petroleum Road, JBSA Fort Sam Houston, Texas 78234., Maughan J; Fort Hays State University, Department of Physics, 600 Park Street, Hays, Kansas 67601., Kitzis N; Fort Hays State University, Department of Physics, 600 Park Street, Hays, Kansas 67601., Buffington GD; Fort Hays State University, Department of Physics, 600 Park Street, Hays, Kansas 67601., Stolarski DJ; TASC Inc., 4241 Woodcock Drive, Suite B-100, San Antonio, Texas 78228., Thomas RJ; 711th Human Performance Wing, Optical Radiation Branch, 4141 Petroleum Road, JBSA Fort Sam Houston, Texas 78234.

Publikováno v: Journal of biomedical optics [J Biomed Opt] 2013 Dec; Vol. 18 (12), pp. 125002.

Selective and potent analgetics derived from cannabinoids.

Autor: Johnson MR, Melvin LS, Althuis TH, Bindra JS, Harbert CA, Milne GM, Weissman A

Publikováno v: Journal of clinical pharmacology [J Clin Pharmacol] 1981 Aug-Sep; Vol. 21 (S1), pp. 271S-282S.

Analgesic and tranquilizing activity of 5,8-disubstituted 2-aminomethyl-3,4-dihydronaphthalenes.

Autor: Welch WM, Plattner JJ, Stratten WP, Harbert CA

Publikováno v: Journal of medicinal chemistry [J Med Chem] 1978 Mar; Vol. 21 (3), pp. 257-63.

4a,9b-trans-8-Fluoro-5-(4-fluorophenyl)-2-[4-(4-fluorophenyl)-4-hydroxybutyl]-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole hydrochloride, a new potent neuroleptic.

Autor: Welch WM, Ewing FE, Harbert CA, Weissman A, Koe BK

Publikováno v: Journal of medicinal chemistry [J Med Chem] 1980 Aug; Vol. 23 (8), pp. 949-52.