Evaluating the efficacy and safety of pozelimab in patients with CD55 deficiency with hyperactivation of complement, angiopathic thrombosis, and protein-losing enteropathy disease: an open-label phase 2 and 3 study.

Autor: Ozen A; Department of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye; The Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Türkiye; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Türkiye., Chongsrisawat V; Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Patumwan, Bangkok, Thailand; King Chulalongkorn Memorial Hospital, Thai Red Cross Society Patumwan, Bangkok, Thailand., Sefer AP; Department of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye; The Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Türkiye; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Türkiye., Kolukisa B; Department of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye; The Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Türkiye; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Türkiye., Jalbert JJ; Regeneron Pharmaceuticals, Sleepy Hollow, NY, USA., Meagher KA; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Brackin T; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Feldman HB; The Genetics Institute, Tel Aviv Sourasky Medical Center, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Baris S; Department of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye; The Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Türkiye; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Türkiye., Karakoc-Aydiner E; Department of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye; The Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Türkiye; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Türkiye., Ergelen R; Department of Radiology, Marmara University, School of Medicine, Istanbul, Türkiye., Fuss IJ; Mucosal Immunity Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Moorman H; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, Laboratory of Clinical Immunology and Microbiology, and Clinical Genomics Program, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Suratannon N; Center of Excellence for Allergy and Clinical Immunology, Division of Allergy, Immunology and Rheumatology, Chulalongkorn University, Patumwan, Bangkok, Thailand; King Chulalongkorn Memorial Hospital, Thai Red Cross Society Patumwan, Bangkok, Thailand., Suphapeetiporn K; Center of Excellence for Medical Genomics, Medical Genomics Cluster, Chulalongkorn University, Patumwan, Bangkok, Thailand; Excellence Center for Genomics and Precision Medicine, Thai Red Cross Society Patumwan, Bangkok, Thailand., Perlee L; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Harari OA; Regeneron Pharmaceuticals, Tarrytown, NY, USA. Electronic address: olivier.harari@regeneron.com., Yancopoulos GD; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Lenardo MJ; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, Laboratory of Clinical Immunology and Microbiology, and Clinical Genomics Program, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

Publikováno v: Lancet (London, England) [Lancet] 2024 Feb 17; Vol. 403 (10427), pp. 645-656. Date of Electronic Publication: 2024 Jan 23.

Impairment of neuronal tyrosine phosphatase STEP worsens post-ischemic inflammation and brain injury under hypertensive condition.

Autor: Paramasivam, Prabu¹ (AUTHOR), Choi, Seong Won¹ (AUTHOR), Poddar, Ranjana¹ (AUTHOR), Paul, Surojit¹ (AUTHOR) spaul@salud.unm.edu

Publikováno v: Journal of Neuroinflammation. 10/22/2024, Vol. 21 Issue 1, p1-20. 20p.

Association Between Coronary Artery Disease and Herpes Zoster: A Cohort Study in Taiwan.

Autor: Lai, Shih-Wei^1,2 (AUTHOR), Kuo, Yu-Hung³ (AUTHOR), Liao, Kuan-Fu^4,5 (AUTHOR) kuanfuliaog@gmail.com

Publikováno v: Open Forum Infectious Diseases. Aug2024, Vol. 11 Issue 8, p1-5. 5p.

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