Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Haran Sivakumar"'
Autor:
Isela Sarahi Rivera, Juliet D French, Mainá Bitar, Haran Sivakumaran, Sneha Nair, Susanne Kaufmann, Kristine M Hillman, Mahdi Moradi Marjaneh, Jonathan Beesley, Stacey L Edwards
Publikováno v:
PLoS Genetics, Vol 20, Iss 11, p e1011490 (2024)
Hormone-dependent cancers (HDCs) share several risk factors, suggesting a common aetiology. Using data from genome-wide association studies, we showed spatial clustering of risk variants across four HDCs (breast, endometrial, ovarian and prostate can
Externí odkaz:
https://doaj.org/article/3dd461429acf494ea56d57eda55dced9
Autor:
Lu Wang, Mainá Bitar, Xue Lu, Sebastien Jacquelin, Sneha Nair, Haran Sivakumaran, Kristine M. Hillman, Susanne Kaufmann, Rebekah Ziegman, Francesco Casciello, Harsha Gowda, Joseph Rosenbluh, Stacey L. Edwards, Juliet D. French
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background Long noncoding RNAs (lncRNAs) have surpassed the number of protein-coding genes, yet the majority have no known function. We previously discovered 844 lncRNAs that were genetically linked to breast cancer through genome-wide assoc
Externí odkaz:
https://doaj.org/article/a83c569fc00d4544a84739b1f231c21e
Publikováno v:
Improving Women's Health Across the Lifespan ISBN: 9781003110682
Improving Women's Health Across the Lifespan
Improving Women's Health Across the Lifespan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05694c77ac64e5af1dab91498a29d51e
https://doi.org/10.1201/9781003110682-8
https://doi.org/10.1201/9781003110682-8
Publikováno v:
International Surgery Journal. 8:2566
Background: Laparoscopic surgery is dominating in the field of hernia. The search for the ideal prosthetic biomaterial has been a longstanding issue with debate over simple versus composite biomaterial and lightweight versus heavyweight meshes. This
Publikováno v:
Journal of Health Communication. 21:155-163
Poor Medicare knowledge is associated with worse health outcomes, especially in low-income patients. We examined the association of health literacy and cognition with actual and perceived Medicare knowledge in a sample of inner-city older adults. We
Publikováno v:
2017 International Conference on Communication and Signal Processing (ICCSP).
The recent years have witnessed significant progress in the automation of human activity recognition in order to realize intelligent environments which are capable of detecting users actions and gestures so that the needed services can be provided au
Autor:
Natasha K. Tuano, Jonathan Beesley, Murray Manning, Wei Shi, Laura Perlaza-Jimenez, Luis F. Malaver-Ortega, Jacob M. Paynter, Debra Black, Andrew Civitarese, Karen McCue, Aaron Hatzipantelis, Kristine Hillman, Susanne Kaufmann, Haran Sivakumaran, Jose M. Polo, Roger R. Reddel, Vimla Band, Juliet D. French, Stacey L. Edwards, David R. Powell, Georgia Chenevix-Trench, Joseph Rosenbluh
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-23 (2023)
Abstract Background Genome-wide association studies (GWAS) have identified > 200 loci associated with breast cancer risk. The majority of candidate causal variants are in non-coding regions and likely modulate cancer risk by regulating gene expressio
Externí odkaz:
https://doaj.org/article/6fa5b74012424fbe8ef3072e8a09b991
Autor:
Skye R. MacGregor, Donald P. McManus, Haran Sivakumaran, Thomas G. Egwang, Moses Adriko, Pengfei Cai, Catherine A. Gordon, Mary G. Duke, Juliet D. French, Natasha Collinson, Remigio M. Olveda, Gunter Hartel, Carlos Graeff-Teixeira, Malcolm K. Jones, Hong You
Publikováno v:
EBioMedicine, Vol 94, Iss , Pp 104730- (2023)
Summary: Background: Schistosomiasis is a disease that significantly impacts human health in the developing world. Effective diagnostics are urgently needed for improved control of this disease. CRISPR-based technology has rapidly accelerated the dev
Externí odkaz:
https://doaj.org/article/27241a5a969d41faa0f509f7a55c7f7d
Autor:
Xiaofeng Du, Donald P. McManus, Juliet D. French, Natasha Collinson, Haran Sivakumaran, Skye R. MacGregor, Conor E. Fogarty, Malcolm K. Jones, Hong You
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Employing the flatworm parasite Schistosoma mansoni as a model, we report the first application of CRISPR interference (CRISPRi) in parasitic helminths for loss-of-function studies targeting the SmfgfrA gene which encodes the stem cell marker, fibrob
Externí odkaz:
https://doaj.org/article/1b457daa571b4084b6414d18c5bffc2a
Autor:
Mahdi Moradi Marjaneh, Jonathan Beesley, Tracy A. O’Mara, Pamela Mukhopadhyay, Lambros T. Koufariotis, Stephen Kazakoff, Nehal Hussein, Laura Fachal, Nenad Bartonicek, Kristine M. Hillman, Susanne Kaufmann, Haran Sivakumaran, Chanel E. Smart, Amy E. McCart Reed, Kaltin Ferguson, Jodi M. Saunus, Sunil R. Lakhani, Daniel R. Barnes, Antonis C. Antoniou, Marcel E. Dinger, Nicola Waddell, Douglas F. Easton, Alison M. Dunning, Georgia Chenevix-Trench, Stacey L. Edwards, Juliet D. French
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background Genetic variants identified through genome-wide association studies (GWAS) are predominantly non-coding and typically attributed to altered regulatory elements such as enhancers and promoters. However, the contribution of non-codi
Externí odkaz:
https://doaj.org/article/5403ef83152d415999f1d71d1048ca89