Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Harald Winter"'
Publikováno v:
SAE International Journal of Fuels and Lubricants. 2:376-386
Publikováno v:
Histochemistry and Cell Biology. 128:65-75
Cochlear outer hair cells (OHCs) terminally differentiate prior to the onset of hearing. During this time period, thyroid hormone (TH) dramatically influences inner ear development. It has been shown recently that TH enhances the expression of the mo
Autor:
Oliver Hendrich, Thomas Weber, Ulrike Zimmermann, Katrin Oelmann, Xiang Wang, Martin C. Göpfert, Justin Albert, Harald Winter, Marlies Knipper, David Z.Z. He, Thorsten J. Schaechinger, Dominik Oliver, Hyun Soon Geisler
Publikováno v:
The Journal of Physiology. 580:451-461
Prestin, a member of the solute carrier (SLC) family SLC26A, is the molecular motor that drives the somatic electromotility of mammalian outer hair cells (OHCs). Its closest reported homologue, zebrafish prestin (zprestin), shares ∼70% strong amino
Autor:
Nikolaus Blin, Marlies Knipper, Markus Pfister, Jutta Engel, Harald Winter, Claudia Braig, Hubert Kalbacher, Nicola Schug, Ulrike Zimmermann, Peter Ruth
Publikováno v:
European Journal of Neuroscience. 24:3372-3380
Mutations of the human otoferlin gene lead to an autosomal recessive nonsyndromic form of prelingual, sensorineural deafness (deafness autosomal recessive 9, DFNB9). Several studies have demonstrated expression of otoferlin in the inner ear and brain
Autor:
Ulrike Zimmermann, Hans-Peter Zenner, Marlies Knipper, Christian Simon, Andrea Müller, Karina Gültig, Hartmut Hahn, Joachim Reichl, Harald Winter, Hubert Löwenheim
Publikováno v:
Tissue Engineering. 11:64-75
In vitro expansion of chondrocytes for tissue-engineering applications is limited by forms of growth arrest known as quiescence and replicative senescence. At the molecular level cyclin-dependent kinase inhibitors (CDKIs) are involved in mediating gr
Autor:
Marlies Knipper, Lukas Rüttiger, Thomas Weber, Ulrike Zimmermann, Juergen-Theodor Fraenzer, Harald Winter
Publikováno v:
e-Neuroforum. 9:113-120
Zusammenfassung In der kritischen Entwicklungsperiode des Innenohres, die mit dem Beginn der Hörfunktion endet - im Menschen ungefähr zwischen der zehnten und zwanzigsten embryonalen Woche, in Nagetieren wie Ratte und Maus zwischen Geburt und postn
Autor:
Thomas Weber, Ulrike Zimmermann, Karin Rohbock, Iris Köpschall, Harald Winter, Hans-Peter Zenner, Andreas F. Mack, Marlies Knipper
Publikováno v:
Proceedings of the National Academy of Sciences. 99:2901-2906
The most impressive property of outer hair cells (OHCs) is their ability to change their length at high acoustic frequencies, thus providing the exquisite sensitivity and frequency-resolving capacity of the mammalian hearing organ. Prestin, a protein
Autor:
Veit Flockerzi, Stephanie Kuhn, Marlies Knipper, Jutta Engel, Sylvia Kasperek, Harald Winter, Martina Knirsch, Lukas Rüttiger, Marc Freichel
Publikováno v:
Channels (Austin, Tex.). 3(5)
Voltage-activated Ca(2+) channels comprise complexes of a pore-forming Ca(V)alpha(1) and auxiliary subunits Ca(V)beta, Ca(V)alpha(2)delta and sometimes Ca(V)gamma. The intracellular Ca(V)beta subunit assists in trafficking and surface expression of t
Autor:
Markus Pfister, Marcus Müller, Lukas Rüttiger, Jutta Engel, Hubert Löwenheim, Bernhard Hirt, Ulrike Zimmermann, Harald Winter, Andreas Bress, Yong Tian, Matthias Sausbier, Marlies Knipper, Frédéric Flamant, Niels Brandt, Jian Zuo, Aude Conscience, Jacques Samarut, Stephanie Kuhn, Peter Ruth
Publikováno v:
Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2009, 29 (8), pp.2581-2587. ⟨10.1523/JNEUROSCI.3557-08.2009⟩
Journal of Neuroscience, Society for Neuroscience, 2009, 29 (8), pp.2581-2587. ⟨10.1523/JNEUROSCI.3557-08.2009⟩
Thyroid hormone receptor β (TRβ) dysfunction leads to deafness in humans and mice. Deafness in TRβ−/−mutant mice has been attributed to TRβ-mediated control of voltage- and Ca2+-activated K+(BK) channel expression in inner hair cells (IHCs).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3938f79ae7fdd064c2c243f522eff988
https://hal.inrae.fr/hal-02655685
https://hal.inrae.fr/hal-02655685
Autor:
Ulrike Zimmermann, Jelka Cimerman, Marlies Knipper, Juergen T. Fraenzer, Harald Winter, Thomas Weber, Claudia Braig
Publikováno v:
Epithelial Anion Transport in Health and Disease: The Role of the SLC26 Transporters Family: Novartis Foundation Symposium 273
The 10-member SLC26 gene family encodes anion exchangers of which SLC26A5 appears to be restricted to the outer hair cells of the inner ear. Here, the so-called prestin protein acts as a molecular motor, thought to be responsible for active mechanica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbf3844b9b3b790ce7f6c4063c34c919
https://doi.org/10.1002/0470029579.ch3
https://doi.org/10.1002/0470029579.ch3