Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Harald Sobek"'
Autor:
Vanessa Schorer, Julian Haas, Robert Stach, Vjekoslav Kokoric, Rüdiger Groß, Jan Muench, Tim Hummel, Harald Sobek, Jan Mennig, Boris Mizaikoff
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The ongoing COVID-19 pandemic represents a considerable risk for the general public and especially for health care workers. To avoid an overloading of the health care system and to control transmission chains, the development of rapid and co
Externí odkaz:
https://doaj.org/article/0151a8495d374bde8cb4d33fe6791ba1
Autor:
Sandra, Dietl, Franziska, Kiefer, Stefanie, Binder, Paul, Walther, Harald, Sobek, Boris, Mizaikoff
Publikováno v:
Journal of Biotechnology. 361:49-56
An efficient capture step for human adenovirus type 5 from cell lysate was developed as an initial virus purification step from cell debris supernatant. Organosilane-based polymer particles were synthesized and experimental monomer screening allowed
Publikováno v:
Analytical Chemistry. 92:3050-3057
Polymer particles with antibody-like affinity, i.e., molecularly imprinted polymers, offer an ideal platform for biopharmaceutical virus purification. In recent years, attempts combining molecular imprinting technology with a variety of visualization
Autor:
Ruediger Gross, Tim Hummel, Boris Mizaikoff, Julian Haas, Robert Stach, Vanessa Schorer, Vjekoslav Kokoric, Jan Muench, Harald Sobek, Jan Menning
Publikováno v:
Sci Rep
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
The ongoing COVID-19 pandemic represents a considerable risk for the general public and especially for health care workers. To avoid an overloading of the health care system and to control transmission chains, the development of rapid and cost-effect
Publikováno v:
TrAC Trends in Analytical Chemistry. 114:218-232
Molecular imprinting enables the fabrication of versatile functional polymers with pre-designed molecular target selectivity, inherent robustness, reusability, and reproducible production. Using advanced synthesis strategies, molecularly imprinted po
Autor:
Alex D. Batista, Soumya Rajpal, Benedikt Keitel, Sandra Dietl, Beatriz Fresco‐Cala, Mehmet Dinc, Rüdiger Groß, Harald Sobek, Jan Münch, Boris Mizaikoff
Publikováno v:
Advanced Materials Interfaces. 9:2270024
Publikováno v:
Analytical Chemistry. 90:5576-5585
Inspired by the recognition processes found in biology such as enzyme-substrate and antibody-antigen interactions, synthetic systems with comparable molecular recognition properties have been investigated during recent years based on molecular imprin
Publikováno v:
Materials; Volume 14; Issue 24; Pages: 7692
Materials
Materials, Vol 14, Iss 7692, p 7692 (2021)
Materials
Materials, Vol 14, Iss 7692, p 7692 (2021)
Virus-imprinted polymers were synthesized via surface imprinting strategies to produce core-shell imprinted particles selective for human adenovirus type 5. High binding affinity of the target virus towards the resulting imprinted layer was confirmed
Publikováno v:
TrAC Trends in Analytical Chemistry. 143:116414
Molecular imprinted polymers are a promising alternative to natural receptors due to their higher stability and lower production costs, yet with comparable performance and high selectivity. The ‘epitope imprinting approach’, in which only a small
Autor:
Alfred Engel, Michael Greif, Rainer Mueller, Marco Thomann, Bernd Nidetzky, Christiane Luley-Goedl, Doris Ribitsch, Helmut Schwab, Sebastian Malik, Christine Jung, Harald Sobek, Katharina Schmoelzer
Publikováno v:
Glycobiology. 26:1097-1106
Sialic acid groups of protein N-glycans are important determinants of biological activity. Exposed at the end of the glycan chain, they are potential targets for glycan remodeling. Sialyltransferases (STs; EC 2.4.99) are the enzymes that catalyze the