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pro vyhledávání: '"Harald Seger"'
Publikováno v:
Journal of the American Chemical Society. 130:8326-8336
Whereas the C-terminal fragment of neuropeptide Y (NPY) has been structurally well-defined both in solution and as membrane-bound, detailed structural information regarding the proline-rich N-terminus is still missing. The systematic variation of eac
Autor:
Harald Seger, Armin Geyer
Publikováno v:
Synthesis. 2006:3224-3230
An improved synthetic protocol transforms D-alduronolactone via a bicyclic dipeptide lactam 2 into pyridone dipeptides with either Boc- or Fmoc-protecting groups 5 or 6. Regioselective bromination of 5 yields dipeptide 10 which is further diversified
Publikováno v:
Acta Crystallographica Section E Structure Reports Online. 61:o2576-o2578
The absolute configuration has been determined for the title compound, C14H18N2O5S, a bicyclic aromatic building block which can act as a rigid fluorescence marker in peptide backbones. In the crystal packing, the two independent molecules of the asy