Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Harald Mackenzie"'
Autor:
Andreas Becker, Emily C. Martin, David Y. Mitchell, Roland Grenningloh, Andrew T. Bender, Julien Laurent, Harald Mackenzie, Andreas Johne
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 2, Pp 325-336 (2020)
Bruton's tyrosine kinase (BTK) is a key regulator of B cell receptor and Fc receptor signaling, and a rational therapeutic target for autoimmune diseases. This first‐in‐human phase I, double‐blind, placebo‐controlled trial investigated the sa
Externí odkaz:
https://doaj.org/article/d2c9cd5493264b6eba52d7fefaa2b7b2
Autor:
David Mitchell, Emily Martin, Andrew Bender, Roland Grenningloh, Julien Laurent, Andreas Johne, Harald Mackenzie, Andreas Becker
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 2, Pp 325-336 (2020)
Clinical and Translational Science
Clinical and Translational Science
Bruton's tyrosine kinase (BTK) is a key regulator of B cell receptor and Fc receptor signaling, and a rational therapeutic target for autoimmune diseases. This first-in-human phase I, double-blind, placebo-controlled trial investigated the safety, to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d7d3bd9840a0b0e18aba002cd3b9b59
https://doaj.org/article/d2c9cd5493264b6eba52d7fefaa2b7b2
https://doaj.org/article/d2c9cd5493264b6eba52d7fefaa2b7b2
Autor:
Harald Mackenzie, Martin W. Lubell, D Svecova, James G. Krueger, Florence Casset-Semanaz, Roland Grenningloh
Publikováno v:
Journal of the American Academy of Dermatology. 81:196-203
Background Interleukin 17 is involved in the pathogenesis of psoriasis, a chronic debilitating disease. Objectives To evaluate the safety/tolerability, immunogenicity, pharmacokinetics/pharmacodynamics, and efficacy of M1095, an anti–interleukin 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed34d69989ca7d761d5c13add5122d41
https://doi.org/10.1016/j.jaad.2019.03.056
https://doi.org/10.1016/j.jaad.2019.03.056