Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Harald Hegen"'
Autor:
Tobias Moser, Fabian Foettinger, Wolfgang Hitzl, Bianka Novotna, Thomas Berger, Gabriel Bsteh, Franziska Di Pauli, Harald Hegen, Barbara Kornek, Dieter Langenscheidt, Johann Sellner
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 6, Pp 1442-1455 (2024)
Abstract Background/Objective Observational real‐world study to analyze the clinical effects of alemtuzumab (ALEM) and subsequent disease‐modifying therapy (DMT) usage in multiple sclerosis (MS). Methods Data retrieved from the Austrian MS treatm
Externí odkaz:
https://doaj.org/article/1d89c8fc3d004d8c9b6d3e781cf52226
Autor:
Anne Zinganell, Klaus Berek, Gabriel Bsteh, Franziska Di Pauli, Verena Rass, Raimund Helbok, Janette Walde, Florian Deisenhammer, Harald Hegen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Lumbar puncture (LP) is recommended in patients with thunderclap headache and negative computed tomography to rule out spontaneous subarachnoid haemorrhage (SAH). Blood contamination of cerebrospinal fluid (CSF) due to traumatic LP poses a d
Externí odkaz:
https://doaj.org/article/6e38a0753196479583db157eb299b15b
Autor:
Harald Hegen, Klaus Berek, Paola Cavalla, Mikael Christiansen, Andreja Emeršič, Massimiliano Di Filippo, Lorenzo Gaetani, Michaela Hassler, Cyra Leurs, Dejan Milosavljevic, Vincent van Pesch, Thor Petersen, Stefan Presslauer, Igal Rosenstein, Uroš Rot, Christine Schnabl, Charlotte Teunissen, Domizia Vecchio, Marco Vercellino, Florian Deisenhammer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundKappa free light chains (κ-FLC) in the cerebrospinal fluid (CSF) are an emerging biomarker in multiple sclerosis (MS).ObjectiveTo investigate whether κ-FLC index has similar diagnostic value in patients with primary progressive multiple s
Externí odkaz:
https://doaj.org/article/f2268023c7d1409780b691eaa832cee5
Autor:
Klaus Berek, Angelika Bauer, Dagmar Rudzki, Michael Auer, Robert Barket, Anne Zinganell, Magdalena Lerch, Livia Hofer, Astrid Grams, Paulina Poskaite, Sebastian Wurth, Thomas Berger, Franziska Di Pauli, Florian Deisenhammer, Harald Hegen, Markus Reindl
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe understanding of the pathophysiology of multiple sclerosis (MS) has evolved alongside the characterization of cytokines and chemokines in cerebrospinal fluid (CSF) and serum. However, the complex interplay of pro- and anti-inflammator
Externí odkaz:
https://doaj.org/article/3c2b943dd08e4064b294faa907aedbec
Autor:
Julia Feige, Klaus Berek, Michael Seiberl, Patrick Hilpold, Wolfgang Hitzl, Franziska Di Pauli, Harald Hegen, Florian Deisenhammer, Eugen Trinka, Andrea Harrer, Peter Wipfler, Tobias Moser
Publikováno v:
Neurology International, Vol 14, Iss 4, Pp 943-951 (2022)
Anti-CD20 therapies decrease the humoral response to SARS-CoV-2 immunization. We aimed to determine the extent of the humoral response to SARS-CoV-2 antigens in correlation with peripheral B-cell dynamics among patients with central nervous system in
Externí odkaz:
https://doaj.org/article/1ff61b322b0643d8b8f79abc1f82656c
Autor:
Klaus Berek, Astrid Grams, Christian Uprimny, Manuela Prieschl, Melanie Ramberger, Iris Unterberger, Florian Deisenhammer, Markus Reindl, Harald Hegen
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Overlap syndromes of anti-NMDA receptor encephalitis and MOG-mediated demyelination have been reported. In this case we provide a long-term longitudinal follow-up of clinical and imaging characteristics as well as of antibody dyna
Externí odkaz:
https://doaj.org/article/9443d5af70ab47bab9d448062f1326d6
Autor:
Harald Hegen, Klaus Berek, Gabriel Bsteh, Michael Auer, Patrick Altmann, Franziska Di Pauli, Astrid Grams, Dejan Milosavljevic, Markus Ponleitner, Paulina Poskaite, Christine Schnabl, Sebastian Wurth, Anne Zinganell, Thomas Berger, Janette Walde, Florian Deisenhammer
Publikováno v:
EBioMedicine, Vol 91, Iss , Pp 104573- (2023)
Summary: Background: Inter-individual courses of multiple sclerosis (MS) are extremely variable. The objective of this study was to investigate whether κ-free light chain (κ-FLC) index and serum neurofilament light (sNfL) have an additive predictiv
Externí odkaz:
https://doaj.org/article/633a6f04b20949cca05f3b92b0be3dd3
Autor:
Klaus Berek, Ronny Beer, Astrid Grams, Raimund Helbok, Anna Lindner, Bettina Pfausler, Alois Schiefecker, Florian Deisenhammer, Harald Hegen
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-6 (2022)
Abstract Background Post herpes simplex virus (HSV) autoimmune encephalitis has been reported mainly in association with NMDA receptor antibodies, however, never with Caspr2 antibodies. Case presentation We report an 82-year old female patient with e
Externí odkaz:
https://doaj.org/article/94f8b538791941e1a452c0bc998ccd78
Autor:
Sven Jarius, Florence Pache, Peter Körtvelyessy, Ilijas Jelčić, Mark Stettner, Diego Franciotta, Emanuela Keller, Bernhard Neumann, Marius Ringelstein, Makbule Senel, Axel Regeniter, Rea Kalantzis, Jan F. Willms, Achim Berthele, Markus Busch, Marco Capobianco, Amanda Eisele, Ina Reichen, Rick Dersch, Sebastian Rauer, Katharina Sandner, Ilya Ayzenberg, Catharina C. Gross, Harald Hegen, Michael Khalil, Ingo Kleiter, Thorsten Lenhard, Jürgen Haas, Orhan Aktas, Klemens Angstwurm, Christoph Kleinschnitz, Jan Lewerenz, Hayrettin Tumani, Friedemann Paul, Martin Stangel, Klemens Ruprecht, Brigitte Wildemann, ; in cooperation with the German Society for Cerebrospinal Fluid Diagnostics and Clinical Neurochemistry
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-33 (2022)
Abstract Background Comprehensive data on the cerebrospinal fluid (CSF) profile in patients with COVID-19 and neurological involvement from large-scale multicenter studies are missing so far. Objective To analyze systematically the CSF profile in COV
Externí odkaz:
https://doaj.org/article/e9740832837b4444a94071945a6b71d4
Autor:
Michael Auer, Anne Zinganell, Harald Hegen, Gabriel Bsteh, Franziska Di Pauli, Klaus Berek, Elena Fava, Sebastian Wurth, Thomas Berger, Florian Deisenhammer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Natalizumab (NTZ) has been used for treatment of highly active relapsing–remitting multiple sclerosis (MS). When stopping NTZ the risk of severe rebound phenomenon has to be considered. We aimed to investigate the use of NTZ in clinical ro
Externí odkaz:
https://doaj.org/article/c9d665bf8d6647dd880506272321e181