Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Harald G.O. Holck"'
1
Effect of the anesthetic and the rate of injection of digitalis upon its lethal dose in cats
Autor: Kazuo K. Kimura, Barbara Bartels, Harald G.O. Holck
Publikováno v: Journal of the American Pharmaceutical Association. American Pharmaceutical Association. 35(12)
In parallel experiments six groups of 12 cats each were anesthetized with urethane and a like number with ether for injection with different dilutions of digitalis according to the U. S. P. XII method. The curves for urethane and for ether were paral
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca4763999db88c0692fb55d4704cbff
https://pubmed.ncbi.nlm.nih.gov/20283123
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4
Effects of β-Diethylaminoethyl Diphenylpropylacetate Hydrochloride on Three Convulsants and on Propallylonal
Autor: Gale E. Demaree, Harald G.O. Holck, Hideko Katayama Kaji
Publikováno v: Journal of Pharmaceutical Sciences. 51:739-742
β-Diethylaminoethyl diphenylpropylacetate hydrochloride (SKF 525-A) increased the LD50s of nikethamide, pentylenetetrazol, and picrotoxin in albino mice when given intraperitoneally 1 hour earlier. The maximum action of picrotoxin in mice subcutaneo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ee470f01ce6921fc1f3d290243a789
https://doi.org/10.1002/jps.2600510808
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5
Studies on sex difference in resistance to ouabain in the albino rat††This project was aided by a grant to the Department of Physiology and Pharmacology College of Pharmacy University of Nebraska, from the Committee on Therapeutic Research Council on Pharmacy and Chemistry, American Medical Association
Autor: Kazuo K. Kimura, Harald G.O. Holck
Publikováno v: Journal of the American Pharmaceutical Association (Scientific ed.). 40:327-332
The presence of sex difference to ouabain, as judged b the average lethal doses (LD50 's) in male and in female rats, has been confirmed and demonstrated. The LD50 at different age levels for rats has been determined and is reported. The influence of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::36281026bb920978e6c5ea2299cee63e
https://doi.org/10.1002/jps.3030400708
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6
Studies on sex variation to picrotoxin in the albino rat††This project was aided by a grant to the Department of Physiology and Pharmacology, College of Pharmacy, University of Nebraska, from the Ella Sachs Plotz Foundation for the Advancement of Scientific Investigation and from the University of Nebraska Research Council
Autor: Harald G.O. Holck
Publikováno v: Journal of the American Pharmaceutical Association (Scientific ed.). 38:604-610
The subcutaneous LD50 of picrotoxin of the adult male albino rat was 87 per cent higher than for the female (5.48 versus 2.82 mg./Kg.); 458 rats were used in these determinations. No sex variation, however, was found in case of albino mice, guinea pi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea15b6202d4dbeb7a9b0d0a52760c932
https://doi.org/10.1002/jps.3030381111
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7
Studies on tolerance and cross-tolerance to nostal (propallylonal; isopropyl-beta-bromallyl barbituric acid)
Autor: Francis A. Robidoux, Carl C. Riedesel, Harald G.O. Holck
Publikováno v: Journal of the American Pharmaceutical Association (Scientific ed.). 39:630-637
Nostal in two concentrations and Alurate, Sigmodal, and Ipral in concentrations corresponding to the lower concentration of Nostal (100 mg./Kg. of powdered laboratory chow) were fed during 28 days. Alurate, Ipral, and the higher concentration of Nost
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4899aa53b8721aa7f171e4c1da044f00
https://doi.org/10.1002/jps.3030391109
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8
The Influence of Experimental Hypo- and Hyperthyroidism on the Effects of Nostal®, Thiopental Sodium, and Hexobarbital Sodium in the Adult Albino Rat*
Autor: Marvin H. Malone, Ira W.M. Hillyard, Harald G.O. Holck
Publikováno v: Journal of the American Pharmaceutical Association (Scientific ed.). 43:276-282
Hypothyroidism produced by either feeding suitable concentrations of propylthiouracil, or by thyroidectomy, greatly increased the average recovery time of both male and female adult albino rats to Nostal®, thiopental sodium., and hexobarbital sodium
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9898f15b0f68c53e3c686f1c42979d8
https://doi.org/10.1002/jps.3030430508
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10
Effect of the Rate of Injection of Digitalis Upon its Lethal Dose in Guinea Pigs††This project was aided by a grant to the Department of Physiology and Pharmacology, College of Pharmacy, University of Nebraska, from Ciba Pharmaceutical Products, Inc
Autor: Tom S. Miya, Harald G.O. Holck
Publikováno v: Journal of the American Pharmaceutical Association (Scientific ed.). 38:64-66
Eighty-four male guinea pigs were divided into seven groups of twelve each and anesthetized with urethane. Each group was tested with varying concentrations of U. S. P. Reference Standard Digitalis (1942) Tincture, using normal saline solution as the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f2c37a222aeb917b9698e8fa23551ea9
https://doi.org/10.1002/jps.3030380203
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