Zobrazeno 1 - 10
of 283
pro vyhledávání: '"Harald, Wajant"'
Autor:
Ying Wang, Enfeng Wang, Mohamed Anany, Simone Füllsack, Yu Henry Huo, Shamit Dutta, Baoan Ji, Luke H. Hoeppner, Sreenivasulu Kilari, Sanjay Misra, Thomas Caulfield, Craig W. Vander Kooi, Harald Wajant, Debabrata Mukhopadhyay
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Tumor necrosis factor-α (TNFα) is a master cytokine which induces expression of chemokines and adhesion molecules, such as intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1), in endothelial cells to initiate t
Externí odkaz:
https://doaj.org/article/d7a930a7344841bea90dc907c25388c8
Autor:
Juan Gamboa Vargas, Jennifer Wagner, Haroon Shaikh, Isabell Lang, Juliane Medler, Mohamed Anany, Tim Steinfatt, Josefina Peña Mosca, Stephanie Haack, Julia Dahlhoff, Maike Büttner-Herold, Carolin Graf, Estibaliz Arellano Viera, Hermann Einsele, Harald Wajant, Andreas Beilhack
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/c4e642d02e2945f18c8e1b5d91ac3077
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/4a11115e5a7a4de88645965f884c0f63
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Tumor necrosis factor (TNF) receptor 1 (TNFR1), TNFR2 and fibroblast growth factor-inducible 14 (Fn14) belong to the TNF receptor superfamily (TNFRSF). From a structural point of view, TNFR1 is a prototypic death domain (DD)-containing receptor. In c
Externí odkaz:
https://doaj.org/article/02e0f32d641943b88a589aab5d186046
Autor:
Olena Zaitseva, Annett Hoffmann, Margaretha Löst, Mohamed A. Anany, Tengyu Zhang, Kirstin Kucka, Armin Wiegering, Christoph Otto, Harald Wajant
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Fibroblast growth factor (FGF)-inducible 14 (Fn14) activates the classical and alternative NFκB (nuclear factor ‘kappa-light-chain-enhancer’ of activated B-cells) signaling pathway but also enhances tumor necrosis factor (TNF)-induced cell death
Externí odkaz:
https://doaj.org/article/86d88a2dc627496a9c30910e4ea2ab82
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Many new immunotherapeutic approaches aim on the stimulatory targeting of receptors of the tumor necrosis factor (TNF) receptor superfamily (TNFRSF) using antibodies with intrinsic or conditional agonism. There is an initial need to characterize corr
Externí odkaz:
https://doaj.org/article/36862e3983684295bd435f3037c112b2
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Fibroblast growth factor-inducible 14 (Fn14) is a member of the tumor necrosis factor (TNF) receptor superfamily (TNFRSF) and is activated by its ligand TNF-like weak inducer of apoptosis (TWEAK). The latter occurs as a homotrimeric molecule in a sol
Externí odkaz:
https://doaj.org/article/5cb6a1d5af264062ae80896d64a16899
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-9 (2021)
Abstract In the early 1990s, it has been described that LTα and LTβ form LTα2β and LTαβ2 heterotrimers, which bind to TNFR1 and LTβR, respectively. Afterwards, the LTαβ2–LTβR system has been intensively studied while the LTα2β–TNFR1 i
Externí odkaz:
https://doaj.org/article/2ebc4ed3aabd473d988fbb86c2ebba08
Autor:
Juan Gamboa Vargas, Jennifer Wagner, Haroon Shaikh, Isabell Lang, Juliane Medler, Mohamed Anany, Tim Steinfatt, Josefina Peña Mosca, Stephanie Haack, Julia Dahlhoff, Maike Büttner-Herold, Carolin Graf, Estibaliz Arellano Viera, Hermann Einsele, Harald Wajant, Andreas Beilhack
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tumor necrosis factor (TNF) receptor-2 (TNFR2) has attracted considerable interest as a target for immunotherapy. Indeed, using oligomeric fusion proteins of single chain-encoded TNFR2-specific TNF mutants (scTNF80), expansion of regulatory T cells a
Externí odkaz:
https://doaj.org/article/19ee7b5e796e491fa6cc6ea161be610b
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 559 (2023)
Adiponectin and the other 15 members of the complement 1q (C1q)/tumor necrosis factor (TNF)-related protein (CTRP) family are secreted proteins composed of an N-terminal variable domain followed by a stalk region and a characteristic C-terminal trime
Externí odkaz:
https://doaj.org/article/17424cd3961b4bd5ac15b72435100207