Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Harald, Stephan"'
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163025 (2016)
Trefoil factor family (TFF) peptides have been shown to effect cell proliferation, apoptosis, migration and invasion of normal cells and various cancer cell lines. In the literature TFF peptides are controversially discussed as tumor suppressors and
Externí odkaz:
https://doaj.org/article/f0843161f11a4a4c9818904507da64eb
Publikováno v:
International Journal of Biological Sciences, Vol 6, Iss 7, Pp 700-715 (2010)
Bone morphogenetic proteins (BMPs) - expressed in the developing retina - are known to be involved in the regulation of cell proliferation and apoptosis in several tumor entities. The objective of this study was to determine the role of the BMP4 path
Externí odkaz:
https://doaj.org/article/d09ae3b319354e01bbee0f599a60e07b
Autor:
Patrick Müller, Rebekka Doliva, Maike Busch, Claudia Philippeit, Harald Stephan, Nicole Dünker
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131467 (2015)
Retinoids have been shown to serve promising therapeutic agents for human cancers, e.g. the treatment of neuroblastoma. Synthetic retinoids, specific for particular retinoic acid (RA) receptors, are tested as new therapy strategies. In the present st
Externí odkaz:
https://doaj.org/article/d9f452c707bb437eb31b5592a9bc072d
Autor:
Maike, Busch, Natalia, Miroschnikov, Jaroslaw Thomas, Dankert, Marc, Wiesehöfer, Klaus, Metz, Harald, Stephan, Nicole, Dünker
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 43(1)
Retinoblastoma (RB) is the most common childhood eye cancer. Chemotherapeutic drugs such as etoposide used in RB treatment often cause massive side effects and acquired drug resistances. Dysregulated genes and miRNAs have a large impact on cancer pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd059a9e51d2792d84e0dd6f65e528fc
https://pubmed.ncbi.nlm.nih.gov/33935126
https://pubmed.ncbi.nlm.nih.gov/33935126
Autor:
Manfred Beier, Jan Große-Kreul, Klaus A. Metz, Harald Stephan, Janina Jasmin Wirtz, Nicole Dünker, Brigitte Royer-Pokora, Maike Busch
Publikováno v:
International Journal of Cancer. 141:549-560
Trefoil factor family (TFF) peptides have been shown to play a pivotal role in oncogenic transformation, tumorigenesis and metastasis by changing cell proliferation, apoptosis, migration and invasion behavior of various cancer cell lines. In the stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::493a15e6db76acb0dcaaaa237d793579
https://doi.org/10.1002/ijc.30768
https://doi.org/10.1002/ijc.30768
Autor:
Janine Altmüller, Sven Rahmann, Christian Gloeckner, Peter Nürnberg, Anton G. Henssen, Martin Peifer, Jessica Theissen, Daniela Beisser, Holger N. Lode, Yassen Assenov, Johannes Köster, Angelika Eggert, Frank Speleman, Corinna Ernst, Kai Oliver Henrich, Barbara Hero, Yvonne Kahlert, Frank Westermann, Matthias Fischer, Alexander Schramm, Harald Stephan, Andrea Odersky, Katleen De Preter, Christoph Plass, Christopher Schröder, Lukas C. Heukamp, E Mahlow, Kathy Astrahantseff, Sangkyun Lee, Frederik Roels, Anne Engesser, Peter Schmezer, Kristina Althoff, Johannes H. Schulte, Moritz Gartlgruber
Publikováno v:
Nature Genetics, 47(8), 872-877
Neuroblastoma is a malignancy of the developing sympathetic nervous system that is often lethal when relapse occurs. We here used whole-exome sequencing, mRNA expression profiling, array CGH and DNA methylation analysis to characterize 16 paired samp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830ec4266f7655faf236e3e441d3d8af
https://doi.org/10.1038/ng.3349
https://doi.org/10.1038/ng.3349
Publikováno v:
Oncology Reports
Retinoblastoma (RB) is the most common malignant intraocular tumor in early childhood. Imminent chemotherapy resistance diminishes the clinical-therapeutic options and emphasizes the necessity for new therapeutic approaches. The present study aimed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c5e3751f2e69014c4b954b13151749
https://pubmed.ncbi.nlm.nih.gov/29192327
https://pubmed.ncbi.nlm.nih.gov/29192327
Autor:
Jo Vandesompele, Kristian W. Pajtler, Lillian Garrett, Andreas Zimmer, Lore Becker, Wolfgang Hartmann, Helmut Fuchs, Massimo Zollo, Thomas Klopstock, Alexander Schramm, A Künkele, Lukas C. Heukamp, Johannes Beckers, Angelika Eggert, Sabine M. Hölter, Ildiko Racz, Johannes H. Schulte, Marion Horsch, Pieter Mestdagh, Ulrich Schüller, Harald Stephan, Natalie Sadowski, Wolfgang Wurst, Tanja Klein-Rodewald, Martin Hrabě de Angelis, Pasqualino De Antonellis, Valerie Gailus-Durner, Frauke Neff, Theresa Thor, Annika K. Wefers, Julia Calzada-Wack
Publikováno v:
International Journal of Cancer. 136:2293-2303
Previous studies have evaluated the role of miRNAs in cancer initiation and progression. MiR-34a was found to be downregulated in several tumors, including medulloblastomas. Here we employed targeted transgenesis to analyze the function of miR-34a in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7321b671c15c504c5172fca79e64f29d
https://doi.org/10.1002/ijc.29294
https://doi.org/10.1002/ijc.29294
Autor:
Alexander Schramm, Harald Stephan, Andrea Odersky, Angelika Eggert, Kristian W. Pajtler, E Mahlow, Ivo Bendix, Sven Lindner, Johannes H. Schulte
Publikováno v:
Oncotarget
In neuroblastoma, the most common solid tumor of childhood, excellent prognosis is associated with extensive Schwann cell (SC) content and high-level expression of the neurotrophin receptor, NTRK1/TrkA, which is known to mediate neuroblastoma cell di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d912fca1b731530d746a0e45a798d2
https://doi.org/10.18632/oncotarget.2611
https://doi.org/10.18632/oncotarget.2611
Autor:
Maike, Busch, Jan, Große-Kreul, Janina Jasmin, Wirtz, Manfred, Beier, Harald, Stephan, Brigitte, Royer-Pokora, Klaus, Metz, Nicole, Dünker
Publikováno v:
International journal of cancer. 141(3)
Trefoil factor family (TFF) peptides have been shown to play a pivotal role in oncogenic transformation, tumorigenesis and metastasis by changing cell proliferation, apoptosis, migration and invasion behavior of various cancer cell lines. In the stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd3787905fae7f6f3030d84ab4bf65f3
https://pubmed.ncbi.nlm.nih.gov/28481041
https://pubmed.ncbi.nlm.nih.gov/28481041