Zobrazeno 1 - 10
of 681
pro vyhledávání: '"Harald, Stein"'
Autor:
Heike Horn, Vindi Jurinovic, Ellen Leich, Sabrina Kalmbach, Julia Bausinger, Annette M. Staiger, Katrin S. Kurz, Peter Möller, Heinz-Wolfram Bernd, Alfred C. Feller, Karoline Koch, Wolfram Klapper, Harald Stein, Martin-Leo Hansmann, Sylvia Hartmann, Gabriel Scheubeck, Martin Dreyling, Wolfgang Hiddemann, Klaus Herfarth, Marianne Engelhard, Andreas Rosenwald, Eva Hoster, German Ott, for the German Low-Grade Lymphoma Study Group (GLSG)
Publikováno v:
HemaSphere, Vol 6, Iss 9, p e767 (2022)
Recently, we have developed novel highly promising gene expression (GE) classifiers discriminating localized nodal (LFL) from systemic follicular lymphoma (SFL) with prognostic impact. However, few data are available in LFL especially concerning hots
Externí odkaz:
https://doaj.org/article/053c8564099e49fb9e4006cd11665282
Autor:
Henry Loeffler-Wirth, Markus Kreuz, Lydia Hopp, Arsen Arakelyan, Andrea Haake, Sergio B. Cogliatti, Alfred C. Feller, Martin-Leo Hansmann, Dido Lenze, Peter Möller, Hans Konrad Müller-Hermelink, Erik Fortenbacher, Edith Willscher, German Ott, Andreas Rosenwald, Christiane Pott, Carsten Schwaenen, Heiko Trautmann, Swen Wessendorf, Harald Stein, Monika Szczepanowski, Lorenz Trümper, Michael Hummel, Wolfram Klapper, Reiner Siebert, Markus Loeffler, Hans Binder, for the German Cancer Aid consortium Molecular Mechanisms for Malignant Lymphoma
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-20 (2019)
Abstract Background Germinal center-derived B cell lymphomas are tumors of the lymphoid tissues representing one of the most heterogeneous malignancies. Here we characterize the variety of transcriptomic phenotypes of this disease based on 873 biopsy
Externí odkaz:
https://doaj.org/article/eb092f16cead48828dfcb25f4bc14f5e
Autor:
Cristina López, Kortine Kleinheinz, Sietse M. Aukema, Marius Rohde, Stephan H. Bernhart, Daniel Hübschmann, Rabea Wagener, Umut H. Toprak, Francesco Raimondi, Markus Kreuz, Sebastian M. Waszak, Zhiqin Huang, Lina Sieverling, Nagarajan Paramasivam, Julian Seufert, Stephanie Sungalee, Robert B. Russell, Julia Bausinger, Helene Kretzmer, Ole Ammerpohl, Anke K. Bergmann, Hans Binder, Arndt Borkhardt, Benedikt Brors, Alexander Claviez, Gero Doose, Lars Feuerbach, Andrea Haake, Martin-Leo Hansmann, Jessica Hoell, Michael Hummel, Jan O. Korbel, Chris Lawerenz, Dido Lenze, Bernhard Radlwimmer, Julia Richter, Philip Rosenstiel, Andreas Rosenwald, Markus B. Schilhabel, Harald Stein, Stephan Stilgenbauer, Peter F. Stadler, Monika Szczepanowski, Marc A. Weniger, Marc Zapatka, Roland Eils, Peter Lichter, Markus Loeffler, Peter Möller, Lorenz Trümper, Wolfram Klapper, ICGC MMML-Seq Consortium, Steve Hoffmann, Ralf Küppers, Birgit Burkhardt, Matthias Schlesner, Reiner Siebert
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Burkitt lymphoma (BL) is the most common pediatric B-cell lymphoma. Here, within the International Cancer Genome Consortium, the authors performed whole genome and transcriptome sequencing of 39 sporadic BL, describing the landscape of mutations, str
Externí odkaz:
https://doaj.org/article/0f2708368b2a4696b47220ee30732ce8
Autor:
Ron Daniel Jachimowicz, Luise Pieper, Sarah Reinke, Artur Gontarewicz, Annette Plütschow, Heinz Haverkamp, Leonie Frauenfeld, Falko Fend, Mathis Overkamp, Franziska Jochims, Christoph Thorns, Martin Leo Hansmann, Peter Möller, Andreas Rosenwald, Harald Stein, Hans Christian Reinhardt, Peter Borchmann, Bastian von Tresckow, Andreas Engert, Wolfram Klapper
Publikováno v:
Haematologica, Vol 106, Iss 6 (2020)
A subset of patients with advanced-stage classical Hodgkin Lymphoma (cHL) relapse or progress following standard treatment. Given their dismal prognosis, identifying this group of patients upfront represents an important medical need. While prior res
Externí odkaz:
https://doaj.org/article/bf2e0be85a7642f9a6ea80dd88841cf7
Autor:
Marita Ziepert, Stefano Lazzi, Raffaella Santi, Federica Vergoni, Massimo Granai, Virginia Mancini, Annette Staiger, Heike Horn, Markus Löffler, Viola Pöschel, Gerhald Held, Gerald Wulf, Lorenz H. Trümper, Norbert Schmitz, Andreas Rosenwald, Elena Sabattini, Kikkeri N. Naresh, Harald Stein, German Ott, Lorenzo Leoncini
Publikováno v:
Haematologica, Vol 105, Iss 11 (2020)
Externí odkaz:
https://doaj.org/article/85938aa2441348e7a06f4c898b4bde77
Autor:
Franziska Lea Schümann, Elisabeth Groß, Marcus Bauer, Christian Rohde, Sarah Sandmann, Denis Terziev, Lutz P. Müller, Guido Posern, Andreas Wienke, Falko Fend, Martin-Leo Hansmann, Wolfram Klapper, Andreas Rosenwald, Harald Stein, Martin Dugas, Carsten Müller-Tidow, Claudia Wickenhauser, Mascha Binder, Thomas Weber
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1842 (2021)
T-cell lymphomas are highly heterogeneous and their prognosis is poor under the currently available therapies. Enhancers of zeste homologue 1 and 2 (EZH1/2) are histone H3 lysine-27 trimethyltransferases (H3K27me3). Despite the rapid development of n
Externí odkaz:
https://doaj.org/article/d63e8094f749409c9ef0bd7310d01020
Autor:
Maria R. Ambrosio, Stefano Lazzi, Giuseppe Lo Bello, Raffaella Santi, Leonardo Del Porro, Maria M. de Santi, Raffaella Guazzo, Lucia Mundo, Luigi Rigacci, Sofia Kovalchuck, Noel Onyango, Alberto Fabbri, Emanuele Cencini, Pier Luigi Zinzani, Francesco Zaja, Francesco Angrilli, Caterina Stelitano, Maria G. Cabras, Giuseppe Spataro, Roshanak Bob, Thomas Menter, Massimo Granai, Gabriele Cevenini, Kikkeri N. Naresh, Harald Stein, Elena Sabattini, Lorenzo Leoncini
Publikováno v:
Haematologica, Vol 104, Iss 1 (2019)
Externí odkaz:
https://doaj.org/article/070664e9f6ba456f9653e517920858cb
Autor:
Reiner Siebert, Martin L. Hansmann, Ralf Küppers, Harald Stein, Thomas Rüdiger, Reza M. Parwaresch, Peter Möller, Irina B. Kaplanskaya, Georgiy A. Frank, Stefan Gesk, Alexander Claviez, Heinz-Wolfram Bernd, Françoise Berger, Thomas F.E. Barth, Jennifer Riemke, Jorge Höppner, Susanne Grohmann, Roland Schmitz, Christian Bastard, Lana Harder, Evelyne Callet-Bauchu, Anna Sotnikova, Wolfram Klapper, José I. Martín-Subero
Supplementary Table 1 from Chromosomal Breakpoints Affecting Immunoglobulin Loci Are Recurrent in Hodgkin and Reed-Sternberg Cells of Classical Hodgkin Lymphoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164fba31e496274ac87ed734c8952595
https://doi.org/10.1158/0008-5472.22365615
https://doi.org/10.1158/0008-5472.22365615
Autor:
Reiner Siebert, Martin L. Hansmann, Ralf Küppers, Harald Stein, Thomas Rüdiger, Reza M. Parwaresch, Peter Möller, Irina B. Kaplanskaya, Georgiy A. Frank, Stefan Gesk, Alexander Claviez, Heinz-Wolfram Bernd, Françoise Berger, Thomas F.E. Barth, Jennifer Riemke, Jorge Höppner, Susanne Grohmann, Roland Schmitz, Christian Bastard, Lana Harder, Evelyne Callet-Bauchu, Anna Sotnikova, Wolfram Klapper, José I. Martín-Subero
Chromosomal breakpoints affecting immunoglobulin (IG) loci are recurrent in many subtypes of B-cell lymphomas. However, despite the predominant B-cell origin of the Hodgkin and Reed-Sternberg (HRS) cells in classical Hodgkin lymphoma (cHL), the prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068587f48af65d9a7f77a021de3ad84d
https://doi.org/10.1158/0008-5472.c.6494778.v1
https://doi.org/10.1158/0008-5472.c.6494778.v1
Autor:
Andreas Engert, Helen Goergen, Jana Markova, Thomas Pabst, Julia Meissner, Josée M. Zijlstra, Zdenek Král, Dennis A. Eichenauer, Martin Soekler, Richard Greil, Stefanie Kreissl, Ruth Scheuvens, Hans Eich, Carsten Kobe, Markus Dietlein, Harald Stein, Michael Fuchs, Volker Diehl, Peter Borchmann
Publikováno v:
HemaSphere, Vol 1, Iss 1 (2017)
Abstract. The international, randomized phase 3 HD15 trial established 6xeBEACOPP as standard therapy for patients with newly diagnosed advanced-stage Hodgkin lymphoma (HL) within the German Hodgkin Study Group (GHSG). We performed a follow-up analys
Externí odkaz:
https://doaj.org/article/5bbc60c61afa496f9b084c2273b060f5