Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Harald, Gross"'
Autor:
Marius Landau, Sherif Elsabbagh, Harald Gross, Adrian CD Fuchs, Anita CF Schultz, Joachim E Schultz
Publikováno v:
eLife, Vol 13 (2024)
The biosynthesis of cyclic 3′,5′-adenosine monophosphate (cAMP) by mammalian membrane-bound adenylyl cyclases (mACs) is predominantly regulated by G-protein-coupled receptors (GPCRs). Up to now the two hexahelical transmembrane domains of mACs we
Externí odkaz:
https://doaj.org/article/0792d42c8d5947e3a0f5cbb05d0d5354
Autor:
Yuankun Yang, Christina E. Steidele, Clemens Rössner, Birgit Löffelhardt, Dagmar Kolb, Thomas Leisen, Weiguo Zhang, Christina Ludwig, Georg Felix, Michael F. Seidl, Annette Becker, Thorsten Nürnberger, Matthias Hahn, Bertolt Gust, Harald Gross, Ralph Hückelhoven, Andrea A. Gust
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The Arabidopsis thaliana Receptor-Like Protein RLP30 contributes to immunity against the fungal pathogen Sclerotinia sclerotiorum. Here we identify the RLP30-ligand as a small cysteine-rich protein (SCP) that occurs in many fungi and oomycet
Externí odkaz:
https://doaj.org/article/dc2c535377794fb79c4f5caa2ac41598
Autor:
Roger D. Castillo Arteaga, Leandro M. Garrido, Brandán Pedre, Irina Helmle, Harald Gross, Bertolt Gust, Gabriel Padilla
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Antibiotic-producing microorganisms usually require one or more self-resistance determinants to survive antibiotic production. The effectors of these mechanisms are proteins that inactivate the antibiotic, facilitate its transport, or modify
Externí odkaz:
https://doaj.org/article/15ba7931acf242dda567d99e55bb95a0
Autor:
Ryan Karongo, Min Ge, Jeannie Horak, Harald Gross, Michal Kohout, Wolfgang Lindner, Michael Lämmerhofer
Publikováno v:
Journal of Chromatography Open, Vol 1, Iss , Pp 100004- (2021)
Amino acid analysis (AAA) is of central importance for the characterization of the amino acid composition of proteins, peptides, pharmaceutical formulations, dietary supplements, in bioanalysis and metabolomics. Common methodologies are based on achi
Externí odkaz:
https://doaj.org/article/dc82387084f848e5924044105d43cfce
Autor:
Nesrine M. Hegazi, Tarik A. Mohamed, Hamada H. Saad, Montaser A. Al-Hammady, Taha A. Hussien, Mohamed-Elamir F. Hegazy, Harald Gross
Publikováno v:
Marine Drugs, Vol 20, Iss 10, p 630 (2022)
Soft corals are recognized as an abundant source of diverse secondary metabolites with unique chemical features and physiologic capabilities. However, the discovery of these metabolites is usually hindered by the traditional protocol which requires a
Externí odkaz:
https://doaj.org/article/8b8b5cd1c1764b7788e92db0b8c1f42d
Autor:
Thomas Majer, Keshab Bhattarai, Jan Straetener, Justus Pohlmann, Patrick Cahill, Markus O. Zimmermann, Marc P. Hübner, Marcel Kaiser, Johan Svenson, Michael Schindler, Heike Brötz-Oesterhelt, Frank M. Boeckler, Harald Gross
Publikováno v:
Marine Drugs, Vol 20, Iss 8, p 532 (2022)
Two new ircinianin-type sesterterpenoids, ircinianin lactone B and ircinianin lactone C (7 and 8), together with five known entities from the ircinianin compound family (1, 3–6) were isolated from the marine sponge Ircinia wistarii. Ircinianin lact
Externí odkaz:
https://doaj.org/article/81201b1953774ebdb89e3abda1c4df48
Autor:
Ariane Théatre, Carolina Cano-Prieto, Marco Bartolini, Yoann Laurin, Magali Deleu, Joachim Niehren, Tarik Fida, Saïcha Gerbinet, Mohammad Alanjary, Marnix H. Medema, Angélique Léonard, Laurence Lins, Ana Arabolaza, Hugo Gramajo, Harald Gross, Philippe Jacques
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Surfactin is a lipoheptapeptide produced by several Bacillus species and identified for the first time in 1969. At first, the biosynthesis of this remarkable biosurfactant was described in this review. The peptide moiety of the surfactin is synthesiz
Externí odkaz:
https://doaj.org/article/67c541f9309e45fbb16342b5e50afd56
Autor:
Feyisara Eyiwumi Oni, Qassim Esmaeel, Joseph Tobias Onyeka, Rasheed Adeleke, Cedric Jacquard, Christophe Clement, Harald Gross, Essaid Ait Barka, Monica Höfte
Publikováno v:
Molecules, Vol 27, Iss 2, p 372 (2022)
Pseudomonas lipopeptides (Ps-LPs) play crucial roles in bacterial physiology, host–microbe interactions and plant disease control. Beneficial LP producers have mainly been isolated from the rhizosphere, phyllosphere and from bulk soils. Despite the
Externí odkaz:
https://doaj.org/article/1d75299dab5a4acaaf8751e0b141e43f
Autor:
Franziska Leipoldt, Javier Santos-Aberturas, Dennis P. Stegmann, Felix Wolf, Andreas Kulik, Rodney Lacret, Désirée Popadić, Daniela Keinhörster, Norbert Kirchner, Paulina Bekiesch, Harald Gross, Andrew W. Truman, Leonard Kaysser
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Metalloproteinase inhibitors are leads for drug development, but their biosynthetic pathways are often unknown. Here the authors show that the acyl branched warhead of actinonin and matlystatins derives from an ethylmalonyl-CoA-like pathway and the s
Externí odkaz:
https://doaj.org/article/33d55bdb2e15447e910a355a7a9c3566
Autor:
Ira Handayani, Hamada Saad, Shanti Ratnakomala, Puspita Lisdiyanti, Wien Kusharyoto, Janina Krause, Andreas Kulik, Wolfgang Wohlleben, Saefuddin Aziz, Harald Gross, Athina Gavriilidou, Nadine Ziemert, Yvonne Mast
Publikováno v:
Marine Drugs, Vol 19, Iss 6, p 316 (2021)
Indonesia is one of the most biodiverse countries in the world and a promising resource for novel natural compound producers. Actinomycetes produce about two thirds of all clinically used antibiotics. Thus, exploiting Indonesia’s microbial diversit
Externí odkaz:
https://doaj.org/article/4af89a7b8d084f6fb84ae8ca7b0174bd