Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Haralambos Hadjivassiliou"'
Autor:
Dan Zhu, Haralambos Hadjivassiliou, Catherine Jennings, David Mikolon, Massimo Ammirante, Sharmistha Acharya, Jon Lloyd, Mahan Abbasian, Rama Krishna Narla, Joseph R. Piccotti, Katie Stamp, Ho Cho, Kandasamy Hariharan
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTCluster of differentiation 47 (CD47) is a transmembrane protein highly expressed in tumor cells that interacts with signal regulatory protein alpha (SIRPα) and triggers a “don’t eat me” signal to the macrophage, inhibiting phagocytosis
Externí odkaz:
https://doaj.org/article/2baf8cb3663d44fba094537b05a4fc5d
Autor:
Gustavo Fenalti, Nicolas Villanueva, Mark Griffith, Barbra Pagarigan, Sirish Kaushik Lakkaraju, Richard Y.-C. Huang, Nadia Ladygina, Alok Sharma, David Mikolon, Mahan Abbasian, Jeffrey Johnson, Haralambos Hadjivassiliou, Dan Zhu, Philip P. Chamberlain, Ho Cho, Kandasamy Hariharan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
CD47 is a transmembrane receptor involved in the regulation of various signalling pathways and a promising target for immuno-oncology therapeutics. Here, the authors present the crystal structure of full-length human CD47 and provide insights into th
Externí odkaz:
https://doaj.org/article/16ac1202277e490cac61cc68b1c66fb7
Publikováno v:
PLoS Biology, Vol 3, Iss 2, p e53 (2005)
Mammalian nuclear hormone receptors (NHRs), such as liver X receptor, farnesoid X receptor, and peroxisome proliferator-activated receptors (PPARs), precisely control energy metabolism. Consequently, these receptors are important targets for the trea
Externí odkaz:
https://doaj.org/article/38fa6c280b6b4efd847ce71a2d7ec5ff
Publikováno v:
Journal of Biological Chemistry. 281:4732-4738
CRS2-associated factors 1 and 2 (CAF1 and CAF2) are closely related proteins that function in concert with chloroplast RNA splicing 2 (CRS2) to promote the splicing of specific sets of group II introns in maize chloroplasts. The CRS2-CAF complexes bi
Publikováno v:
RNA (New York, N.Y.), vol 20, iss 5
Sad1 is an essential splicing factor initially identified in a genetic screen in Saccharomyces cerevisiae for snRNP assembly defects. Based on sequence homology, Sad1, or USP39 in humans, is predicted to comprise two domains: a zinc finger ubiquitin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efdd78a0df7975b2117c05e53c5bbdce
https://escholarship.org/uc/item/9j06710k
https://escholarship.org/uc/item/9j06710k
Publikováno v:
Methods in enzymology. 472
The spliceosome is a complex small nuclear (sn)RNA-protein machine that removes introns from pre-mRNAs via two successive phosphoryl transfer reactions. For each splicing event, the spliceosome is assembled de novo on a pre-mRNA substrate and a compl
p90 ribosomal protein S6 kinases (RSKs) integrate upstream signals through two catalytic domains. Autophosphorylation of Ser386 by the regulatory C-terminal kinase domain (CTD) is thought to be essential for activation of the N-terminal kinase domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0398d67d6c2110de62e785c0cbe82b79
https://europepmc.org/articles/PMC3634365/
https://europepmc.org/articles/PMC3634365/
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 102(38)
Appropriate response to nutritional stress is critical for animal survival and metabolic health. To better understand regulatory networks that sense and respond to nutritional availability, we developed a quantitative RT-PCR strategy to monitor chang
Publikováno v:
PLoS biology, vol 3, iss 2
PLoS Biology, Vol 3, Iss 2, p e53 (2005)
PLoS Biology
PLoS Biology, Vol 3, Iss 2, p e53 (2005)
PLoS Biology
Mammalian nuclear hormone receptors (NHRs), such as liver X receptor, farnesoid X receptor, and peroxisome proliferator-activated receptors (PPARs), precisely control energy metabolism. Consequently, these receptors are important targets for the trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0ef627acd517f781b312dd5304ff25
https://escholarship.org/uc/item/5gr848c3
https://escholarship.org/uc/item/5gr848c3
Autor:
Alice Barkan, Gerard J. Ostheimer, Haralambos Hadjivassiliou, Daniel P. Kloer, Brian W. Matthews
Publikováno v:
Journal of Molecular Biology. 350:185