Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Haralambos, Gavras"'
Autor:
Trevor David Rhone, Romakanta Bhattarai, Haralambos Gavras, Bethany Lusch, Misha Salim, Marios Mattheakis, Daniel T. Larson, Yoshiharu Krockenberger, Efthimios Kaxiras
Publikováno v:
Advanced Theory and Simulations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b85f5d34d1a6ea2df714be67988899ea
https://doi.org/10.1002/adts.202300019
https://doi.org/10.1002/adts.202300019
Autor:
Joel M. Neutel, Russell Jaffe, Andrea Rosanoff, Rebecca B. Costello, Haralambos Gavras, Ronald J. Elin, Jayashree Mani
Publikováno v:
Hypertension. 78
This study tests the hypothesis that RMJH-111b, a novel drug candidate, can improve blood pressure (BP) in hypertensive adults without the gastrointestinal distress that is often experienced with oral magnesium (Mg) treatment. A Phase 1 / 2 study tes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::109bd77cc6022df1cb4e0c598dc14506
https://doi.org/10.1161/hyp.78.suppl_1.p109
https://doi.org/10.1161/hyp.78.suppl_1.p109
Autor:
Sofia Leonardi, Gerasimos A. Rassias, Haralambos Gavras, Konstantinos Afratis, Christos Koutsakis, Dionisia Rigopoulou, Zoi Piperigkou, Dionissios Papaioannou, Nikos K. Karamanos, Eleanna Vachlioti
Publikováno v:
European journal of medicinal chemistry. 210
Βradykinin stimulation of B2 receptor is known to activate the oncogenic ERK pathway and overexpression of bradykinin receptors B1 and B2 has been reported to occur in glioma, colorectal and cervical cancers. B1R and B2R antagonists have been shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec43b82c77f29064f3c7f87960215c37
https://pubmed.ncbi.nlm.nih.gov/33139111
https://pubmed.ncbi.nlm.nih.gov/33139111
Autor:
S. Maragkoudakis, Panagiotis Vardas, Haralambos Gavras, Irene Gavras, Joanna E. Kontaraki, Fragiskos I. Parthenakis, M. Marketou, Evangelos A. Zacharis
Publikováno v:
Journal of Human Hypertension. 28:450-455
Bradykinin participates in various hypertensive processes, exerted via its type 1 and type 2 receptors (BKR1 and BKR2). The aim of the study was to investigate BKR1 and BK2R gene expression in peripheral monocytes in patients with essential hypertens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24bf699a1f84b3409d51b3fb725dfee
https://doi.org/10.1038/jhh.2013.133
https://doi.org/10.1038/jhh.2013.133
Autor:
Irene Gavras, Haralambos Gavras
Publikováno v:
Journal of Hypertension. 30:655-659
It is widely believed that salt-dependent hypertension is induced and maintained by expansion of intravascular fluid volume resulting from excessive retention of sodium. The purpose of this brief article is to present a series of arguments in support
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b42dc660d0abdc749e844696ac50000
https://doi.org/10.1097/hjh.0b013e32834f6de1
https://doi.org/10.1097/hjh.0b013e32834f6de1
Autor:
Hillary Johnston-Cox, Dan Yang, Milka Koupenova, Haralambos Gavras, Katya Ravid, Vassilis I. Zannis, Alexander Vezeridis
Publikováno v:
Circulation. 125:354-363
Background— The cAMP-elevating A 2b adenosine receptor (A 2b AR) controls inflammation via its expression in bone marrow cells. Methods and Results— Atherosclerosis induced by a high-fat diet in apolipoprotein E–deficient mice was more pronounc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::821fba6d7102cef2501b3b9818a7a7a0
https://doi.org/10.1161/circulationaha.111.057596
https://doi.org/10.1161/circulationaha.111.057596
Autor:
D. Vougia, Maria E. Marketou, Joanna E. Kontaraki, J. Konstantinou, Irene Gavras, P. Tsiverdis, J. Logakis, Panos E. Vardas, A. Spanaki, Haralambos Gavras, Frangiskos I. Parthenakis
Publikováno v:
Journal of Hypertension. 35:e333-e334
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9eeb73c31b57d43d2ad8f5594ab165c
https://doi.org/10.1097/01.hjh.0000523990.19919.57
https://doi.org/10.1097/01.hjh.0000523990.19919.57
Publikováno v:
Hypertension Research. 33:772-777
Following the introduction of angiotensin-converting enzyme (ACE) inhibitors in the treatment of hypertension and ischemic heart disease, there has been increasing interest in the bradykinin-mediated aspects of ACE inhibition. Several preclinical and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c903fe0e9879dedf97d9ae89d3df65
https://doi.org/10.1038/hr.2010.82
https://doi.org/10.1038/hr.2010.82
Publikováno v:
Journal of Biological Chemistry. 285:5555-5568
The angiotensin converting enzyme (ACE) catalyzes the extracellular formation of angiotensin II, and degradation of bradykinin, thus regulating blood pressure and renal handling of electrolytes. We have previously shown that exogenously added ACE eli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc02a076a6f22d1a841273bd1eb39cc
https://doi.org/10.1074/jbc.m109.074740
https://doi.org/10.1074/jbc.m109.074740
Publikováno v:
American Journal of Hypertension. 22:1320-1325
BACKGROUND The angiotensin II (AngII) type 1 receptor (AT1) regulates cardiovascular function by activating various signal pathways. The purpose of this study was to evaluate the effects of a mutant AT1 receptor on AngII-responding blood pressure and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a1b82973f2a45e3b90c00aba0f35fe
https://doi.org/10.1038/ajh.2009.181
https://doi.org/10.1038/ajh.2009.181