Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Haralabos Zorbas"'
Autor:
Michael Groessl, Alexander E. Egger, Paul J. Dyson, Haralabos Zorbas, Stefanie Zorbas-Seifried, Christian G. Hartinger, Michael A. Jakupec, Bernhard K. Keppler, Walter Berger
Publikováno v:
Chemistry & Biodiversity. 5:2140-2155
The promising drug candidate indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019) is the second Ru-based anticancer agent to enter clinical trials. In this review, which is an update of a paper from 2006 (Hartinger et al., J. Inorg.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fbdbc7d50e2bdbe880d67aae86fea8
https://doi.org/10.1002/cbdv.200890195
https://doi.org/10.1002/cbdv.200890195
Autor:
Markus Galanski, Haralabos Zorbas, Stefanie Zorbas-Seifried, Bernhard K. Keppler, Christian G. Hartinger, Kristof Meelich
Publikováno v:
Biochemistry. 45:14817-14825
(SP-4-2)-Bis(2-aminoethanol)dichloroplatinum(II) (KP1356) and (SP-4-2)-bis[(R)-(-)-2-aminobutanol)]dichloroplatinum(II) (KP1433) are promising cytotoxic agents capable of changing their chemical structure depending on the pH value. On the basis of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cdc1ea83304a751f21c953bb10eb7f1
https://doi.org/10.1021/bi061063i
https://doi.org/10.1021/bi061063i
Autor:
Stefanie Zorbas-Seifried, Haralabos Zorbas, Christian G. Hartinger, Bernhard K. Keppler, Michael A. Jakupec, Bernd Kynast
Publikováno v:
Journal of Inorganic Biochemistry. 100:891-904
Indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019 or FFC14A) is just the second ruthenium-based anticancer agent after NAMI-A which was developed to the stage of clinical trials. Important steps in the mode of action of KP1019 are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4157961190336de5f3a1f48a49ba0ca
https://doi.org/10.1016/j.jinorgbio.2006.02.013
https://doi.org/10.1016/j.jinorgbio.2006.02.013
Autor:
Wilfried Körner, Petra Heffeter, Siegfried Knasmüller, Michael Micksche, Hedwig Sutterlüty, Bernhard K. Keppler, Nikolai Graf von Keyserlingk, Haralabos Zorbas, Stefan Wild, Alla Korynevska, Leonilla Elbling, Michael A. Jakupec, Walter Berger
Publikováno v:
Biochemical Pharmacology. 71:426-440
Aim of this study was to investigate the anticancer properties of the new lanthanum compound [tris(1,10-phenanthroline)lanthanum(III)]trithiocyanate (KP772; FFC24). In vitro, growth inhibition by KP772 was comparable for >60 tumour cell models with I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9b0e2d595d302730d5ab42016cbe55
https://doi.org/10.1016/j.bcp.2005.11.009
https://doi.org/10.1016/j.bcp.2005.11.009
Autor:
Haralabos Zorbas, Bernhard K. Keppler
Publikováno v:
ChemBioChem. 6:1157-1166
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9090d1feb5cf6152fb6c7dff4fc7ec1
https://doi.org/10.1002/cbic.200400427
https://doi.org/10.1002/cbic.200400427
Publikováno v:
Inorganica Chimica Acta. 290:237-246
Mono- and bis(platinum) complexes containing N -alkyl-ethylenediamine units of the type { cis -PtCl 2 [H 2 NCH 2 CH 2 NH(CH 2 ) n CH 3 ]} ( n =8, 9, 11, 15) and [{ cis- PtCl 2 (H 2 NCH 2 CH 2 NH)} 2 (CH 2 ) n ] ( n =6, 8, 10, 12) and their correspond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d341734abf87d60027612ec899874c8
https://doi.org/10.1016/s0020-1693(99)00156-5
https://doi.org/10.1016/s0020-1693(99)00156-5
Autor:
Haralabos Zorbas
Publikováno v:
Angewandte Chemie. 111:1121-1124
Eine Zeit-Raum-Umkehr ermoglicht die Durchfuhrung der Polymerase-Kettenreaktion (PCR) im Durchflusbetrieb: Das mobile Reaktionsgemisch wird kontinuierlich durch einen Glas-Mikrochip gepumpt und durchlauft dabei mehrfach drei Zonen konstanter Temperat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6545ba88542bf927929e2778672f6284
https://doi.org/10.1002/(sici)1521-3757(19990419)111:8<1121::aid-ange1121>3.0.co
https://doi.org/10.1002/(sici)1521-3757(19990419)111:8<1121::aid-ange1121>3.0.co
Autor:
Haralabos Zorbas
Publikováno v:
Angewandte Chemie International Edition. 38:1055-1058
A time-space conversion enables the polymerase chain reaction (PCR) to be carried out in a continuous-flow process: the mobile reaction mixture is pumped continuously through a glass microchip and passes many times through three constant temperature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1be7af6c53f720d6eaf114f2fc09d3d
https://doi.org/10.1002/(sici)1521-3773(19990419)38:8<1055::aid-anie1055>3.0.co
https://doi.org/10.1002/(sici)1521-3773(19990419)38:8<1055::aid-anie1055>3.0.co
Autor:
Ulrike Gärtner, Monika Niggemann, Theo Rein, Darren A. Natale, Melvin L. DePamphilis, Haralabos Zorbas
Publikováno v:
Journal of Biological Chemistry. 272:10021-10029
An unusual “densely methylated island” (DMI), in which all cytosine residues are methylated on both strands for 127-516 base pairs, has been reported at mammalian origins of DNA replication. This report had far-reaching implications in understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589c0637da7977c77a7b9d4a937d07a6
https://doi.org/10.1074/jbc.272.15.10021
https://doi.org/10.1074/jbc.272.15.10021
Publikováno v:
Journal of Cellular Biochemistry. 63:1-22
Inverted repeats occur nonrandomly in the DNA of most organisms. Stem-loops and cruciforms can form from inverted repeats. Such structures have been detected in pro- and eukaryotes. They may affect the supercoiling degree of the DNA, the positioning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0668031dc9e0a02fdb2059924ea53575
https://doi.org/10.1002/(sici)1097-4644(199610)63:1<1::aid-jcb1>3.0.co
https://doi.org/10.1002/(sici)1097-4644(199610)63:1<1::aid-jcb1>3.0.co