Lung adenocarcinomas with mucinous histology: clinical, genomic, and immune microenvironment characterization and outcomes to immunotherapy-based treatments and KRAS ^G12C inhibitors.

Autor: Di Federico A; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Hong L; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Elkrief A; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Thummalapalli R; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Cooper AJ; Massachusetts General Hospital, Boston, MA, USA., Ricciuti B; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Digumarthy S; Massachusetts General Hospital, Boston, MA, USA., Alessi JV; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Gogia P; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Pecci F; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Makarem M; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Gandhi MM; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Garbo E; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Saini A; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., De Giglio A; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Favorito V; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Scalera S; Clinical Trial Center, Biostatistics and Bioinformatics Division, IRCCS Regina Elena National Cancer Institute, Rome, Italy., Cipriani L; Clinical Trial Center, Biostatistics and Bioinformatics Division, IRCCS Regina Elena National Cancer Institute, Rome, Italy., Marinelli D; Department of Experimental Medicine, Sapienza University, Rome, Italy., Haradon D; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Nguyen T; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Haradon J; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Voligny E; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Vaz V; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Gelsomino F; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Sperandi F; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Melotti B; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Ladanyi M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Zhang J; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Gibbons DL; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Heymach JV; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Nishino M; Department of Radiology, Brigham and Women's Hospital and Department of Imaging, Dana-Farber Cancer Institute, Boston, MA, USA., Lindsay J; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Rodig SJ; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Pfaff K; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Sholl LM; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Wang X; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA., Johnson BE; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Jänne PA; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Rekhtman N; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Maugeri-Saccà M; Clinical Trial Center, Biostatistics and Bioinformatics Division, IRCCS Regina Elena National Cancer Institute, Rome, Italy., Heist RS; Massachusetts General Hospital, Boston, MA, USA., Ardizzoni A; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Awad MM; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Arbour KC; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Schoenfeld AJ; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Vokes NI; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Luo J; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address: Jia_Luo@dfci.harvard.edu.

Publikováno v: Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2024 Dec 03. Date of Electronic Publication: 2024 Dec 03.