Short-term NAD ⁺ supplementation prevents hearing loss in mouse models of Cockayne syndrome.

Autor: Okur MN; 1Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224 USA., Mao B; 2Laboratory of Cochlear Development, National Institute on Deafness and Other Communication Disorders, Bethesda, MD 20892 USA., Kimura R; 1Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224 USA., Haraczy S; 2Laboratory of Cochlear Development, National Institute on Deafness and Other Communication Disorders, Bethesda, MD 20892 USA., Fitzgerald T; 3Mouse Auditory Testing Core, National Institute on Deafness and Other Communication Disorders, Bethesda, MD 20892 USA., Edwards-Hollingsworth K; 2Laboratory of Cochlear Development, National Institute on Deafness and Other Communication Disorders, Bethesda, MD 20892 USA., Tian J; 1Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224 USA., Osmani W; 1Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224 USA., Croteau DL; 1Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224 USA., Kelley MW; 2Laboratory of Cochlear Development, National Institute on Deafness and Other Communication Disorders, Bethesda, MD 20892 USA., Bohr VA; 1Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224 USA.; 4Danish Center for Healthy Aging, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen N, Denmark.

Publikováno v: NPJ aging and mechanisms of disease [NPJ Aging Mech Dis] 2020 Jan 07; Vol. 6, pp. 1. Date of Electronic Publication: 2020 Jan 07 (Print Publication: 2020).

NAD metabolism: Role in senescence regulation and aging.

Autor: Chini, Claudia Christiano Silva^1,2 (AUTHOR) chini.claudia@mayo.edu, Cordeiro, Heidi Soares^1,2 (AUTHOR), Tran, Ngan Le Kim³ (AUTHOR), Chini, Eduardo Nunes^1,2 (AUTHOR)

Publikováno v: Aging Cell. Jan2024, Vol. 23 Issue 1, p1-22. 22p.

Long‐term NAD+ supplementation prevents the progression of age‐related hearing loss in mice.

Autor: Okur, Mustafa N.¹ (AUTHOR) mokur@hs.uci.edu, Sahbaz, Burcin Duan¹ (AUTHOR), Kimura, Risako¹ (AUTHOR), Manor, Uri² (AUTHOR), Patel, Jaimin¹ (AUTHOR), Park, Jae‐Hyeon¹ (AUTHOR), Andrade, Leo² (AUTHOR), Puligilla, Chandrakala¹ (AUTHOR), Croteau, Deborah L.^1,3 (AUTHOR), Bohr, Vilhelm A.^1,4 (AUTHOR) vbohr@sund.ku.dk

Publikováno v: Aging Cell. Sep2023, Vol. 22 Issue 9, p1-14. 14p.

Beyond Pellagra—Research Models and Strategies Addressing the Enduring Clinical Relevance of NAD Deficiency in Aging and Disease.

Autor: Feuz, Morgan B.¹ (AUTHOR), Meyer-Ficca, Mirella L.^1,2 (AUTHOR), Meyer, Ralph G.^1,2 (AUTHOR) ralph.meyer@usu.edu

Publikováno v: Cells (2073-4409). Feb2023, Vol. 12 Issue 3, p500. 23p.

Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD⁺ signaling.

Autor: Okur, Mustafa N.¹ (AUTHOR), Fang, Evandro F.^1,2 (AUTHOR), Fivenson, Elayne M.¹ (AUTHOR), Tiwari, Vinod¹ (AUTHOR) vinod.tiwari@nih.gov, Croteau, Deborah L.¹ (AUTHOR), Bohr, Vilhelm A.^1,3 (AUTHOR) vbohr@nih.gov

Publikováno v: Aging Cell. Dec2020, Vol. 19 Issue 12, p1-16. 16p.