Altered Affinity Maturation in Primary Response to (4-hydroxy-3-nitrophenyl) Acetyl (NP) after Autologous Reconstitution of Irradiated C57BL/6 Mice

Autor: Jacques Urbain, Annette Van Acker, Maryse Brait, Carl De Trez, Georgette Vansanten

Publikováno v: Clinical and Developmental Immunology, Vol 9, Iss 3, Pp 119-125 (2002)
Developmental Immunology, 9 (3
Vrije Universiteit Brussel
Developmental Immunology

Immune responses developing in irradiated environment are profoundly altered. The memory antiarsonate response of A/J mice is dominated by a major clonotype encoded by a single gene segment combination called CRIA. In irradiated and autoreconstituted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c31dea15168c89f17eb90e79b651c81
https://doaj.org/article/567a2261ac6043e4a877de9b8c470aee

Adjuvant effects of CpG oligodeoxynucleotides on responses against T-independent type 2 antigens

Autor: Kovarik, Jiri, Bozzotti, P, Tougne, Chantal, Davis, HL, Lambert, Paul Henri, Krieg, AM, Siegrist, Claire-Anne

Publikováno v: Immunology, Vol. 102, No 1 (2001) pp. 67-76

Oligodeoxynucleotides containing CpG motifs (CpG-ODN) are potent in vitro B-cell activators and they have been successfully used to increase in vivo antibody responses to T-dependent peptide and protein antigens. In contrast, the use of CpG-ODN to en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6f5d5718325ace99a65727c5a62d401d
https://europepmc.org/articles/PMC1783157/

T helper 1 (Th1) and Th2 characteristics start to develop during T cell priming and are associated with an immediate ability to induce immunoglobulin class switching

Autor: Sanjiv A. Luther, Kai-Michael Toellner, Richard K.-W. Choy, Daniel Man-Yuen Sze, Hans Acha-Orbea, Dale R. Taylor, Ian C. M. MacLennan

Publikováno v: The Journal of Experimental Medicine
Journal of Experimental Medicine, vol. 187, no. 8, pp. 1193-1204

The respective production of specific immunoglobulin (Ig)G2a or IgG1 within 5 d of primary immunization with Swiss type mouse mammary tumor virus [MMTV(SW)] or haptenated protein provides a model for the development of T helper 1 (Th1) and Th2 respon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c94712a5fccd646dbb48192b8abad1b
https://pubmed.ncbi.nlm.nih.gov/9547331

Induction of antibodies against a peptide hapten does not require covalent linkage between the hapten and a class II presentable T helper peptide

Autor: Sarobe, P. (Pablo), Lasarte, J.J. (Juan José), Golvano, J.J. (José Javier), Gullon, A. (Arturo), Civeira, M.P. (María Pilar), Prieto, J. (Jesús), Borras-Cuesta, F. (Francisco)

Following immunization with a complex antigen, a B cell internalizes this antigen through an interaction between its surface immunoglobulins and an epitope of the antigen. Enzymatic processing of the antigen frees one or more short peptide determinan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1111::81483295946d183b969ce5a0c347971e
https://hdl.handle.net/10171/21676

Demonstration of antibodies against Brucella melitensis 16M lipopolysaccharide and native hapten in human sera by enzyme-linked immunosorbent assay

Autor: L Fernandex-Lago, R Diaz

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
instname

An enzyme-linked immunosorbent assay (ELISA) for the detection and quantification of human immunoglobulin G (IgG), IgA, and IgM antibodies against Brucella melitensis 16M by using lipopolysaccharide (LPS) and native hapten (NH) as antigens is describ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55539ad4d1f05b5634db3ba65a58265d
https://hdl.handle.net/10171/29446