Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Haoyun Duan"'
Autor:
Hongyan Liu, Benxiang Qi, Guanghui Liu, Haoyun Duan, Zongyi Li, Zhaoying Shi, Yonglong Chen, Wai Kit Chu, Qingjun Zhou, Bi Ning Zhang
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109875- (2024)
Summary: The cornea and sclera are distinct adjacent tissues, yet their stromal cells originate from common neural crest cells (NCCs). Sclerocornea is a disease characterized by an indistinguishable boundary between the cornea and sclera. Previously,
Externí odkaz:
https://doaj.org/article/cc4eda781617490e84a8262b6bd9a451
Publikováno v:
Eye and Vision, Vol 10, Iss 1, Pp 1-16 (2023)
Abstract Objective Stem cell therapy is a promising strategy for the treatment of corneal endothelial dysfunction, and the need to find functional alternative seed cells of corneal endothelial cells (CECs) is urgent. Here, we determined the feasibili
Externí odkaz:
https://doaj.org/article/f640108c874d43a29157c31a264d50a4
Autor:
Shengqian Dou, Qun Wang, Bin Zhang, Chao Wei, Huijin Wang, Ting Liu, Haoyun Duan, Hui Jiang, Mingna Liu, Xiaolin Qi, Qingjun Zhou, Lixin Xie, Weiyun Shi, Hua Gao
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-18 (2022)
Abstract Keratoconus is a common ectatic corneal disorder in adolescents and young adults that can lead to progressive visual impairment or even legal blindness. Despite the high prevalence, its etiology is not fully understood. In this study, we per
Externí odkaz:
https://doaj.org/article/fd17d0ae833d4198bcc0395f1b03ada4
Autor:
Xiaomin Liu, Qingjun Zhou, Yusen Huang, Zheng Fan, Haoyun Duan, Menghan Wang, Zongyi Li, Lixin Xie
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Background Mammalian lens regeneration holds great potential as a cataract therapy. However, the mechanism of mammalian lens regeneration is unclear, and the methods for optimization remain in question. Methods We developed an in vitro lens
Externí odkaz:
https://doaj.org/article/3ffb572ec5ca4780a19359c039def70b
Autor:
Qun Wang, Shengqian Dou, Bin Zhang, Hui Jiang, Xia Qi, Haoyun Duan, Xin Wang, Chunxiao Dong, Bi Ning Zhang, Lixin Xie, Yihai Cao, Qingjun Zhou, Weiyun Shi
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 880-893 (2022)
The corneal endothelium is critical for maintaining corneal clarity by mediating hydration through barrier and pump functions. Progressive loss of corneal endothelial cells during aging has been associated with the development of Fuchs endothelial co
Externí odkaz:
https://doaj.org/article/746721f6d499471782e9a098e26dbccc
Autor:
Shengqian Dou, Qun Wang, Bin Zhang, Chao Wei, Huijin Wang, Ting Liu, Haoyun Duan, Hui Jiang, Mingna Liu, Xiaolin Qi, Qingjun Zhou, Lixin Xie, Weiyun Shi, Hua Gao
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/1558b3210d5640018e34dbd5adcf7175
Autor:
Yajie Gong, Haoyun Duan, Xin Wang, Can Zhao, Wenjing Li, Chunxiao Dong, Zongyi Li, Qingjun Zhou
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Background The corneal endothelium maintains corneal hydration through the barrier and pump function, while its dysfunction may cause corneal edema and vision reduction. Considering its development from neural crest cells (NCCs), here we inv
Externí odkaz:
https://doaj.org/article/3cda536c4d7c4687808483ba57715741
Autor:
Zongyi Li, Haoyun Duan, Yanni Jia, Can Zhao, Wenjing Li, Xin Wang, Yajie Gong, Chunxiao Dong, Bochao Ma, Shengqian Dou, Bin Zhang, Dongfang Li, Yihai Cao, Lixin Xie, Qingjun Zhou, Weiyun Shi
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 1 (2022)
Human pluripotent stem cells (hPSCs) hold great promise for the treatment of various human diseases. However, their therapeutic benefits and mechanisms for treating corneal endothelial dysfunction remain undefined. Here, we developed a therapeutic re
Externí odkaz:
https://doaj.org/article/5b56dec15ff64ae59c31547d7d66ac76
Autor:
Lingling Yang, Songmei Zhang, Haoyun Duan, Muchen Dong, Xiaoli Hu, Zhaohua Zhang, Yao Wang, Xiaoping Zhang, Weiyun Shi, Qingjun Zhou
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 1, Pp 46-57 (2019)
Abstract Chronic inflammation and severe dry eye are two important adverse factors for the successful transplant of cultured limbal stem cells. The aim of this study was to investigate the effects of inflammation and hyperosmotic stress (a key pathol
Externí odkaz:
https://doaj.org/article/79ae22bb7b64487ea68e73cdffedbba7
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150731 (2016)
Transplantation of ex vivo expanded corneal limbal stem cells (LSCs) has been the main treatment for limbal stem cell deficiency, although the shortage of donor corneal tissues remains a major concern for its wide application. Due to the development
Externí odkaz:
https://doaj.org/article/da289d61b06e4e99bf63bc0ee49cc167