Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Haoying Xu"'
Publikováno v:
Biomedical Journal, Vol 47, Iss 1, Pp 100605- (2024)
Background: Curcumin ameliorates bone loss by inhibiting osteoclastogenesis. Curcumin inhibits RANKL-promoted autophagy in osteoclast precursors (OCPs), which mediates its anti-osteoclastogenic effect. But the role of RANKL signaling in curcumin-regu
Externí odkaz:
https://doaj.org/article/c4ad0bef9136478b881cb7b28614468e
Autor:
Bing Feng, Xudong Feng, Yingduo Yu, Haoying Xu, Qingqing Ye, Ruitian Hu, Xinru Fang, Feiqiong Gao, Jian Wu, Qiaoling Pan, Jiong Yu, Guanjing Lang, Lanjuan Li, Hongcui Cao
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Background Mesenchymal stem cell (MSC) treatment plays a major role in the management of acute lung injury (ALI), and neutrophils are the initial line of defense against ALI. However, the effect of MSCs on neutrophils in ALI remains mostly u
Externí odkaz:
https://doaj.org/article/45dc2df242f84e8589ae54a6872006ca
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 794 (2024)
Many drug and therapeutic modalities have emerged over the past few years. However, successful commercialization is dependent on their safety and efficacy evaluations. Several preclinical models are available for drug-screening and safety evaluations
Externí odkaz:
https://doaj.org/article/284ed1e104ba43c18f10c83e57a23740
Autor:
Yanlei Yang, Junfen Fan, Haoying Xu, Linyuan Fan, Luchan Deng, Jing Li, Di Li, Hongling Li, Fengchun Zhang, Robert Chunhua Zhao
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-16 (2021)
Abstract Long noncoding RNAs are crucial factors for modulating adipogenic differentiation, but only a few have been identified in humans. In the current study, we identified a previously unknown human long noncoding RNA, LYPLAL1-antisense RNA1 (LYPL
Externí odkaz:
https://doaj.org/article/3bbf67040ed041f8a145864ac6acaf15
Autor:
Haoying Xu, Yanlei Yang, Linyuan Fan, Luchan Deng, Junfen Fan, Di Li, Hongling Li, Robert Chunhua Zhao
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2021)
Abstract Background Obesity has received increasing attention because of its widespread worldwide occurrence and many threats to health. Human adipose-derived mesenchymal stem cells (hADSCs) are a critical source of adipocytes. Long noncoding RNAs (l
Externí odkaz:
https://doaj.org/article/6cb66a1c80914e03aee244778a0ae4ae
Autor:
Qigu Yao, Wenyi Chen, Feiqiong Gao, Yuchen Wu, Lingling Zhou, Haoying Xu, Jong Yu, Xinli Zhu, Lan Wang, Lanjuan Li, Hongcui Cao
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 847 (2023)
The noninvasive diagnosis of cholangiocarcinoma (CCA) is insufficiently accurate. Therefore, the discovery of new prognostic markers is vital for the understanding of the CCA mechanism and related treatment. The information on CCA patients in The Can
Externí odkaz:
https://doaj.org/article/9f9a48c071964d3b86fcf46cd329e789
Publikováno v:
Journal of Personalized Medicine, Vol 13, Iss 3, p 441 (2023)
Background: Although increasing preclinical studies have emphasized the benefits of exosome-related therapies, the efficacy of mesenchymal stromal cell (MSC)-derived extracellular vesicles (EV) for liver injury is unclear. In this work, a pooled anal
Externí odkaz:
https://doaj.org/article/9507f39cd2c3447eb4073b0201c372ed
Autor:
Yiru Zhang, Qigu Yao, Yong Pan, Xinru Fang, Haoying Xu, Tingxiao Zhao, Guangqi Zhu, Tianan Jiang, Shibo Li, Hongcui Cao
Publikováno v:
Cancers, Vol 15, Iss 3, p 682 (2023)
Objective: In recent years, the anti-programmed cell death protein-1 and its ligand (PD-1/PD-L1) or combination therapies have been recommended as an alternative emerging choice of treatment for oncology patients. However, the efficacy and adverse ev
Externí odkaz:
https://doaj.org/article/762ec030257147d089c7dd68e98472f4
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93394 (2014)
Notch signaling pathway defines an evolutionarily conserved mechanism in cell-fate determination in a broad spectrum of developmental processes through local cell interactions. mind bomb (mib) encodes an E3 ubiquitin ligase that is involved in Notch
Externí odkaz:
https://doaj.org/article/d0e48ab3889341f3bef8c22ea236f43a
Autor:
Brun Ulfhake, Shumin Zhou, Xiaoyue Wang, Huafei Li, Haoying Xu, Shihua Wang, Xingyan An, Gongxin Peng, Shuang Peng, Tingdong Yan, Robert Chunhua Zhao, Jingqi Liu, Zhen Xu, Guangliang Shan, Georgina M. Ellison-Hughes, Sihuan Xu, Zhi Zheng, Jing Li, Sasanka Chakrabarti, Lee Wei Lim, Eric Gilson, Fengchun Zhang, Huanxing Su, Qin Han, Yinghao Cao, Yan-Qing Ma, Antonio Cano, Jiao Wang, Jinming Gao, Ilia Stambler, Hongcui Cao, Alexey Moskalev, Calogero Caruso, Luchan Deng, Yan Liu, Xuebin Qu, Rongjia Zhu, Zhe Li, Dayong Xu, Zhonghui Zhang, Holly M. Brown-Borg, Kyung Jin Min, Wei Hou, Hongling Li, Kunlin Jin, Ronghua Jin, Jiaqi Zhu, Yingmei Feng, Tao Huang, Jianshe Yan, Yanlei Yang, Feng Wei
Publikováno v:
Cell Research. 31:1244-1262
The infusion of coronavirus disease 2019 (COVID-19) patients with mesenchymal stem cells (MSCs) potentially improves clinical symptoms, but the underlying mechanism remains unclear. We conducted a randomized, single-blind, placebo-controlled (29 pati