Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Haoxing Wu"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The prodrug design strategy offers a potent solution for improving therapeutic index and expanding drug targets. However, current prodrug activation designs are mainly responsive to endogenous stimuli, resulting in unintended drug release an
Externí odkaz:
https://doaj.org/article/fb70002ec1f14987af8e9beb313e3b39
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/d681f59eb7e04c5aa95b00b3dd38a44b
Publikováno v:
Frontiers in Energy Research, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/e74c9416760d44ae9a082c918844d041
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
The high incidence of prostate cancer (PCa) increases the need for progress in its diagnosis, staging, and precise treatment. The overexpression of tumor-specific receptors for peptides in human cancer cells, such as gastrin-releasing peptide recepto
Externí odkaz:
https://doaj.org/article/8bb2e1cb1a4049fa97ccba3688d38a93
Publikováno v:
Molecules, Vol 26, Iss 2, p 276 (2021)
Novel bioorthogonal tools enable the development of new biomedical applications. Here we report the concise synthesis of a series of aryl-functionalized cyclobutene analogues using commercially available starting materials. Our study demonstrates tha
Externí odkaz:
https://doaj.org/article/cdae400e444e4d9abd43189348ab4917
Publikováno v:
Molecules, Vol 25, Iss 23, p 5640 (2020)
Prodrugs, which remain inert until they are activated under appropriate conditions at the target site, have emerged as an attractive alternative to drugs that lack selectivity and show off-target effects. Prodrugs have traditionally been activated by
Externí odkaz:
https://doaj.org/article/4f09ebdf249443a393cc056e8283fcdc
Autor:
Huan Cao, Jinyao Zhu, Jianhua Zhang, Lei Yang, Xutong Guo, Rong Tian, Haoxing Wu, Yiwen Li, Zhipeng Gu
Publikováno v:
Chemistry of Materials. 35:2191-2201
Publikováno v:
Organic Letters. 24:5293-5297
Autor:
Haojie Yang, Hongbao Sun, Yinghan Chen, Fang Yuan, Cheng Yang, Xiaoai Wu, Wei Chen, Yong Liang, Haoxing Wu
Despite the tetrazine bioorthogonal reaction holding immense potential in biomedical research and drug discovery, its in vivo performance has been strongly challenged by the inverse correlation between the physiological stability and reactivity of te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8cac87ab52cbe1a6a14119329a49309
https://doi.org/10.21203/rs.3.rs-2923887/v1
https://doi.org/10.21203/rs.3.rs-2923887/v1
Publikováno v:
Organic Letters. 24:3368-3372