Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Haowen Ran"'
Autor:
Haohao Huang, Songyang Zhang, Yuanyuan Li, Zhaodan Liu, Lanjuan Mi, Yan Cai, Xinzheng Wang, Lishu Chen, Haowen Ran, Dake Xiao, Fangye Li, Jiaqi Wu, Tingting Li, Qiuying Han, Liang Chen, Xin Pan, Huiyan Li, Tao Li, Kun He, Ailing Li, Xuemin Zhang, Tao Zhou, Qing Xia, Jianghong Man
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
How ROS levels are regulated in cancer stem cells and their contribution to cancer resistance is currently not clear. Here, the authors show that prohibitin regulates mitochondrial ROS production stabilizing the peroxidase PRDX3 and this accounts for
Externí odkaz:
https://doaj.org/article/717939013c2d493084da56349c8594b5
Autor:
Lanjuan Mi, Qinghui Qi, Haowen Ran, Lishu Chen, Da Li, Dake Xiao, Jiaqi Wu, Yan Cai, Songyang Zhang, Yuanyuan Li, Bohan Li, Jiong Xie, Haohao Huang, Tao Li, Tao Zhou, Ailing Li, Ji Qi, Fangye Li, Jianghong Man
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glioma stem-like cells (GSCs) are a subset of tumor cells that initiate malignant growth and promote the therapeutic resistance of glioblastoma, the most lethal primary brain tumor. Ribosome biogenesis is an essential cellular process to maintain cel
Externí odkaz:
https://doaj.org/article/07b9ddd034f242f78a2afe360ac3c128
Autor:
Lishu Chen, Tao Zhou, Ji Qi, Lanjuan Mi, Haowen Ran, Yan Cai, Dake Xiao, Jianghong Man, Jiaqi Wu, Yuanyuan Li, Tao Li, Fangye Li, Haohao Huang, Bohan Li, Qinghui Qi, Jiong Xie, Songyang Zhang, Ailing Li, Da Li
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
Glioma stem-like cells (GSCs) are a subset of tumor cells that initiate malignant growth and promote the therapeutic resistance of glioblastoma, the most lethal primary brain tumor. Ribosome biogenesis is an essential cellular process to maintain cel
Autor:
Fangye Li, Haohao Huang, Dake Xiao, Kun He, Qiu-Ying Han, Jiaqi Wu, Lanjuan Mi, Ailing Li, Tao Zhou, Zhaodan Liu, Songyang Zhang, Xinzheng Wang, Yan Cai, Yuanyuan Li, Jianghong Man, Xue-Min Zhang, Hui-Yan Li, Tingting Li, Qing Xia, Xin Pan, Haowen Ran, Liang Chen, Lishu Chen, Tao Li
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Low levels of reactive oxygen species (ROS) are crucial for maintaining cancer stem cells (CSCs) and their ability to resist therapy, but the ROS regulatory mechanisms in CSCs remains to be explored. Here, we discover that prohibitin (PHB) specifical
Autor:
Haowen Ran, Jianghong Man, Lanjuan Mi, Da Li, Xu Yan, Jin Wu, Tao Li, Jeremy N. Rich, Sai-Sai Guo, Dake Xiao, Xiao-Yan Zhan, Songyang Zhang, Haohao Huang, Jiuwei Cui, Kun He, Yuanyuan Li, Lishu Chen, Zhang Xuemin, Xinzheng Wang, Tao Zhou, Qiu-Ying Han, Yu Yu, Tingting Li, Ailing Li, Shideng Bao
Publikováno v:
The Journal of Experimental Medicine
Zhan et al. reveal that glioma stem-like cells (GSCs) evade type I IFN suppression through MBD3/NuRD complex–mediated STAT1 downregulation, thereby allowing GSCs to initiate a tumor in the inhospitable microenvironment in glioblastoma (GBM).
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Autor:
Jianghong Man, Li Ailing, Haohao Huang, Tao Zhou, Lishu Chen, Qiu-Ying Han, Xinzheng Wang, Lanjuan Mi, Songyang Zhang, Dake Xiao, Saisai Guo, Haowen Ran, Da Li
Publikováno v:
Cancer letters. 454
Glioblastoma (GBM) is an incurable primary brain tumor that is highly resistant to current treatments. Glioma stem-like cells (GSCs) are an aggressive population of glioma cells that not only initiate malignant growth, but also promote therapeutic re