Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Haoshu Fang"'
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110787- (2024)
Summary: Non-invasive, real-time monitorable indicators for early assessment of sepsis-associated myocardial injury (SMI) are still lacking. We aimed to develop non-invasive, real-time indicators for early assessment of SMI using bedside heart rate (
Externí odkaz:
https://doaj.org/article/e81ebe1e7c3642f99f98e927817c69d7
Autor:
Qilun Zhang, Xuting Shen, Xin Yuan, Jing Huang, Yaling Zhu, Tengteng Zhu, Tao Zhang, Haibo Wu, Qian Wu, Yinguang Fan, Jing Ni, Leilei Meng, Anyuan He, Chaowei Shi, Hao Li, Qingsong Hu, Jian Wang, Cheng Chang, Fan Huang, Fang Li, Meng Chen, Anding Liu, Shandong Ye, Mao Zheng, Haoshu Fang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Oxidative stress-induced lipid accumulation is mediated by lipid droplets (LDs) homeostasis, which sequester vulnerable unsaturated triglycerides into LDs to prevent further peroxidation. Here we identify the upregulation of lipopolysacchari
Externí odkaz:
https://doaj.org/article/cd628ea85d2a4584a3d193cdf6fe7360
Autor:
Jin Wang, Jun Ye, Liqi Yang, Xiangfeng Chen, Haoshu Fang, Zhou Liu, Guomei Xia, Yafei Zhang, Zhenhua Zhang
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Recently, with the rapid progress of metagenomic next-generation sequencing (mNGS), inconsistency between mNGS results and clinical diagnoses has become more common. There is currently no reasonable explanation for this, and the i
Externí odkaz:
https://doaj.org/article/c653809da2fa452a95a15c7d7009127c
Autor:
Suwen Bai, Wenxuan Hou, Yanheng Yao, Jialin Meng, Yuan Wei, Fangfang Hu, Xianyu Hu, Jing Wu, Ning Zhang, Ruihuan Xu, Faqing Tian, Benguo Wang, Hailan Liao, Yinan Du, Haoshu Fang, Wei He, Yehai Liu, Bing Shen, Juan Du
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 535-546 (2022)
Tumor cells actively release large quantities of exosomes, which pivotally participate in the regulation of cancer biology, including head and neck cancer (HNC). Exosome biogenesis and release are complex and elaborate processes that are considered t
Externí odkaz:
https://doaj.org/article/df6691b74c364108a8e1aeee2b38ad3a
Autor:
Juan Du, Suwen Bai, Yuan Wei, Wenxuan Hou, YanHeng Yao, Junwei Zhu, Yinan Du, Bing Shen, Haoshu Fang
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
Introduction Diabetes-associated endothelial barrier function impairment might be linked to disturbances in Ca2+ homeostasis. To study the role and molecular mechanism of Orais–vascular endothelial (VE)-cadherin signaling complex and its downstream
Externí odkaz:
https://doaj.org/article/40a30d2a5fa84b21a84acf1b4fe44f0b
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Inflammation, which is induced by the immune response, is recognized as the driving factor in many diseases, including infections and inflammatory diseases, metabolic disorders and cancers. Genetic variations in pivotal genes associated with the immu
Externí odkaz:
https://doaj.org/article/b78d5e802e274e79a3bd4d7b1618ee6a
Publikováno v:
Journal of Inflammation, Vol 15, Iss 1, Pp 1-9 (2018)
Abstract Background High levels of serum lipopolysaccharide (LPS) were observed in sepsis patients with liver injury and high mortality. However, the role of liver in modulation LPS induced inflammatory injury was ill investigated. In the present stu
Externí odkaz:
https://doaj.org/article/ee9fcf1e48334dfd92a3c3074e2222f2
Autor:
Yaling Zhu, Qingjie Zeng, Fang Li, Haoshu Fang, Zhimin Zhou, Tao Jiang, Chao Yin, Qing Wei, Yujie Wang, Jiming Ruan, Jianzhen Huang
Publikováno v:
Frontiers in Genetics, Vol 11 (2021)
Epigenetic regulation of gene expression has been reported in the pathogenesis of metabolic disorders such as diabetes and liver steatosis in humans. However, the molecular mechanisms of fatty liver hemorrhagic syndrome (FLHS) in chickens have been r
Externí odkaz:
https://doaj.org/article/67846885db2942c38aca3f36e8752b02
Autor:
Mao Zheng, Xiaobing Wang, Hui Guo, Yinguang Fan, Zichen Song, Zhaohui Lu, Jinquan Wang, Changcheng Zheng, Lin Dong, Yan Ma, Yuyou Zhu, Haoshu Fang, Shandong Ye
Publikováno v:
Journal of Diabetes Research, Vol 2021 (2021)
The induction of inflammation and cytokine storm was proposed to play a critical role in COVID-19. This study is aimed at investigating the relationship between glucose metabolism and the inflammatory state of inpatients with COVID-19. 71 inpatients
Externí odkaz:
https://doaj.org/article/2fe958a94fe44e509f961c4e504a94c6
Autor:
Zhixiang He, Zichen Song, Leilei Meng, Wenhui Cheng, Fan Huang, Mao Zheng, Wenhui Xu, Rong Xiao, Haoshu Fang, Yaling Zhu
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Sepsis is an organ dysfunction caused by the dysregulated inflammatory response to infection. Lipopolysaccharide-binding protein (LBP) binds to lipopolysaccharide (LPS) and modulates the inflammatory response. A rare systematic study has been reporte
Externí odkaz:
https://doaj.org/article/499be52e24434432be85dae98eda58e3