Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Haoshen Shi"'
Autor:
Haoshen Shi, Zhuoran Yin, Yosef Koronyo, Dieu-Trang Fuchs, Julia Sheyn, Miyah R. Davis, Jered W. Wilson, Milica A. Margeta, Kristen M. Pitts, Shawn Herron, Seiko Ikezu, Tsuneya Ikezu, Stuart L. Graham, Vivek K. Gupta, Keith L. Black, Mehdi Mirzaei, Oleg Butovsky, Maya Koronyo-Hamaoui
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-22 (2022)
Abstract Single cell RNA sequencing studies identified novel neurodegeneration-associated microglial (MGnD/DAM) subtypes activated around cerebral amyloid plaques. Micro-RNA (miR)-155 of the TREM2-APOE pathway was shown to be a key transcriptional re
Externí odkaz:
https://doaj.org/article/6295f0a29d264d44a2eee4921e0f8872
Autor:
Altan Rentsendorj, Koen Raedschelders, Dieu-Trang Fuchs, Julia Sheyn, Vineet Vaibhav, Rebecca A. Porritt, Haoshen Shi, Jargalsaikhan Dagvadorj, Juliana de Freitas Germano, Yosef Koronyo, Moshe Arditi, Keith L. Black, Bhakta Prasad Gaire, Jennifer E. Van Eyk, Maya Koronyo-Hamaoui
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionOsteopontin (OPN; also known as SPP1), an immunomodulatory cytokine highly expressed in bone marrow-derived macrophages (BMMΦ), is known to regulate diverse cellular and molecular immune responses. We previously revealed that glatiramer
Externí odkaz:
https://doaj.org/article/0841f2b649ca4207b40888b9d0da4ad7
Autor:
Haoshen Shi, Yosef Koronyo, Altan Rentsendorj, Dieu-Trang Fuchs, Julia Sheyn, Keith L. Black, Nazanin Mirzaei, Maya Koronyo-Hamaoui
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The retina has been increasingly investigated as a site of Alzheimer’s disease (AD) manifestation for over a decade. Early reports documented degeneration of retinal ganglion cells and their axonal projections. Our group provided the first evidence
Externí odkaz:
https://doaj.org/article/751f43151f20454eadfd239f4d763558
Autor:
Nazanin Mirzaei, Haoshen Shi, Mia Oviatt, Jonah Doustar, Altan Rentsendorj, Dieu-Trang Fuchs, Julia Sheyn, Keith L. Black, Yosef Koronyo, Maya Koronyo-Hamaoui
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
The neurosensory retina emerges as a prominent site of Alzheimer’s disease (AD) pathology. As a CNS extension of the brain, the neuro retina is easily accessible for noninvasive, high-resolution imaging. Studies have shown that along with cognitive
Externí odkaz:
https://doaj.org/article/73e54d03b5684d3b807fbea2ccdd215d
Autor:
Haoshen Shi, Elizabeth A. Berger
Publikováno v:
Mediators of Inflammation, Vol 2018 (2018)
Background. Inflammation is an important contributor to the pathogenesis of diabetic retinopathy (DR). NF-κB is a master transcriptional regulator for numerous inflammatory genes. Although NF-κB is comprised of multiple subunits, p65 has received t
Externí odkaz:
https://doaj.org/article/3d639e1e68a047ffba777fd0084fe7e2
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0185383 (2017)
Diabetic retinopathy is a visually debilitating disease with limited treatment options available. Compound 49b, a β-adrenergic receptor agonist, has been demonstrated to effectively reduce disease pathogenesis associated with diabetic retinopathy. W
Externí odkaz:
https://doaj.org/article/f124442664f74c59be2317af3515f726
Autor:
Yosef Koronyo, Altan Rentsendorj, Nazanin Mirzaei, Giovanna C. Regis, Julia Sheyn, Haoshen Shi, Ernesto Barron, Galen Cook-Wiens, Anthony R. Rodriguez, Rodrigo Medeiros, Joao A. Paulo, Veer B. Gupta, Andrei A. Kramerov, Alexander V. Ljubimov, Jennifer E. Van Eyk, Stuart L. Graham, Vivek K. Gupta, John M. Ringman, David R. Hinton, Carol A. Miller, Keith L. Black, Antonino Cattaneo, Giovanni Meli, Mehdi Mirzaei, Dieu-Trang Fuchs, Maya Koronyo-Hamaoui
Publikováno v:
Acta Neuropathologica. 145:409-438
Alzheimer’s disease (AD) pathologies were discovered in the accessible neurosensory retina. However, their exact nature and topographical distribution, particularly in the early stages of functional impairment, and how they relate to disease progre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1910fe6b18859e163ae74740beb59648
https://doi.org/10.1007/s00401-023-02548-2
https://doi.org/10.1007/s00401-023-02548-2
Autor:
Haoshen Shi, Yosef Koronyo, Dieu‐Trang Fuchs, Julia Sheyn, Ousman Jallow, Krishna Mandalia, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Andrei A. Kramerov, Alexander V. Ljubimov, Debra Hawes, Carol A. Miller, Keith L. Black, Roxana O. Carare, Maya Koronyo‐Hamaoui
Publikováno v:
Alzheimer's & Dementia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b8160ebe7670e02eb594f448e2b7635
https://doi.org/10.1002/alz.13086
https://doi.org/10.1002/alz.13086
Autor:
Haoshen Shi, Yosef Koronyo, Julia Sheyn, Krishna Mandalia, Dieu‐Trang Fuchs, Vivek K Gupta, Stuart Graham, Keith L Black, Mehdi Mirzaei, Carol A Miller, Maya Koronyo‐Hamaoui
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb23f2114f4b9fdc82c36179ec0e0c68
https://doi.org/10.1002/alz.063251
https://doi.org/10.1002/alz.063251
Autor:
Yosef Koronyo, Altan Rentsendorj, Nazanin Mirzaei, Giovanna C. Regis, Julia Sheyn, Haoshen Shi, Ernesto Barron, Galen Cook-Wiens, Anthony R. Rodriguez, Rodrigo Medeiros, Joao A. Paulo, Veer B. Gupta, Andrei A. Kramerov, Alexander V. Ljubimov, Jennifer E. Van Eyk, Stuart L. Graham, Vivek K. Gupta, John M. Ringman, David R. Hinton, Carol A. Miller, Keith L. Black, Antonino Cattaneo, Giovanni Meli, Mehdi Mirzaei, Dieu-Trang Fuchs, Maya Koronyo-Hamaoui
Alzheimer’s disease (AD) pathologies were discovered in the easily accessible neurosensory retina. Yet, their specific nature, topographical distribution, and relationship with disease status remain undefined. Here, we histologically determined bur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec03b24209d33ac620b6e6ff6dbc08bf
https://doi.org/10.21203/rs.3.rs-2152218/v1
https://doi.org/10.21203/rs.3.rs-2152218/v1
