Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Haosen Zhao"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Acute myeloid leukaemia (AML) is a fatal haematopoietic malignancy and is treated with the conventional combination of cytarabine (Ara-C) and daunorubicin (Dau). The survival rate of AML patients is lower due to the cardiotoxicity of daunoru
Externí odkaz:
https://doaj.org/article/a962fdb0db0a4792968f51011b161210
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Traumatic spinal cord injury (SCI), often resulting from external physical trauma, initiates a series of complex pathophysiological cascades, with severe cases leading to paralysis and presenting significant clinical challenges. Traditional diagnosti
Externí odkaz:
https://doaj.org/article/1c1a29b77af14f239dbcf3ed3dc9e300
Autor:
Chang Xu, He Tian, Haosen Zhao, Huicong Feng, Jiachen Sun, Zipeng Zhou, Yue Guo, Zhanpeng Guo, Yajiang Yuan, Chuanjie Zhang, Dan Li, Xifan Mei
Publikováno v:
Materials & Design, Vol 233, Iss , Pp 112203- (2023)
Spinal cord injury (SCI) can cause very serious bodily harm or even paralysis. However, all clinical drugs require long-term use to relieve the disease, causing toxicity and side effects. Zinc tends to activate the self-defense system to repair SCI,
Externí odkaz:
https://doaj.org/article/e9d4e80a193d4f3d9952d6a8d280f29e
Autor:
Yang Li, Jialei Hu, Meng Wang, Yihang Yuan, Fangyuan Zhou, Haosen Zhao, Tianming Qiu, Leilei Liang
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract Liver metastasis is the leading cause of death in colorectal carcinoma (CRC). However, little is known about the mechanisms of transferring effector messages between the primary tumor and the site of metastasis. Exosomes provide a novel tran
Externí odkaz:
https://doaj.org/article/f7e86c2d02a8428c9d85db9b0203633b
Publikováno v:
Materials Today Bio, Vol 18, Iss , Pp 100529- (2023)
The hyperinflammation microenvironment after spinal cord injury (SCI) remains a great challenge for neural regeneration. Methylprednisolone has been used to reduce the inflammatory response after SCI, but it is controversial due to side effects assoc
Externí odkaz:
https://doaj.org/article/041f3ac5d9534f24adcb1d3b9c133c76
Publikováno v:
Materials & Design, Vol 225, Iss , Pp 111465- (2023)
Inflammatory bowel disease (IBD) is a life-threatening organ dysfunction amplified by complex interactions between genetic, environmental, and immune factors. Sulfasalazine (Sul), an immunosuppressant, can potentially treat autoinflammation-induced d
Externí odkaz:
https://doaj.org/article/ac6ab6d0cbd042eeae939abf1bdb7294
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 24, Iss 1, Pp 38-43 (2021)
Objective(s): Resveratrol has been recognized as a potential therapeutic drug in spinal cord injury (SCI). Sirtuin 1 (SIRT1) is vital in the regulation of apoptosis and cell stress response. In this research, our purpose was to explore the mechanisms
Externí odkaz:
https://doaj.org/article/552a00ac5acb4067b3a6904ce9292fe6
Autor:
Xuepu Zhang, Yue Zhang, Limin Yang, Yuexin Wu, Xiaohu Ma, Gang Tong, Zhaoliang Ban, Haosen Zhao
Publikováno v:
Clinics, Vol 77 (2022)
Abstract Objectives Osteoblasts are derived from Bone Marrow-derived Mesenchymal Stem Cells (BM-MSCs), which play an indispensable role in bone formation. In this study, the authors aim to investigate the role of IRF4 in the osteogenic differentiatio
Externí odkaz:
https://doaj.org/article/41b3463240c846f59e15bc38dc7447c5
Publikováno v:
Journal of Materials Chemistry A. 11:6181-6190
H-bonding and van der Waals forces affect the self-assembly between molecules, explaining the self-assembly process of the gel. The spatial configuration of the dimer and the forces between molecules can be visualized through the ESP graph.