Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Haoping Liu"'
Autor:
Tingting Zhou, Norma V. Solis, Michaela Marshall, Qing Yao, Rachel Garleb, Mengli Yang, Eric Pearlman, Scott G. Filler, Haoping Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Patients with decreased levels of CD18 (β2 integrins) suffer from life-threatening bacterial and fungal infections. CD11b, the α subunit of integrin CR3 (CD11b/CD18, αMβ2), is essential for mice to fight against systemic Candida albicans
Externí odkaz:
https://doaj.org/article/0f81f176012742c69ace6098249d696b
Control of β-glucan exposure by the endo-1,3-glucanase Eng1 in Candida albicans modulates virulence.
Autor:
Mengli Yang, Norma V Solis, Michaela Marshall, Rachel Garleb, Tingting Zhou, Daidong Wang, Marc Swidergall, Eric Pearlman, Scott G Filler, Haoping Liu
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010192 (2022)
Candida albicans is a major opportunistic pathogen of humans. It can grow as morphologically distinct yeast, pseudohyphae and hyphae, and the ability to switch reversibly among different forms is critical for its virulence. The relationship between m
Externí odkaz:
https://doaj.org/article/341b2e941afc4fd7bb65971452e7a3d7
Autor:
Selma S Alkafeef, Shelley Lane, Clinton Yu, Tingting Zhou, Norma V Solis, Scott G Filler, Lan Huang, Haoping Liu
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008881 (2020)
Iron is an essential nutrient required as a cofactor for many biological processes. As a fungal commensal-pathogen of humans, Candida albicans encounters a range of bioavailable iron levels in the human host and maintains homeostasis with a conserved
Externí odkaz:
https://doaj.org/article/85a2ccd0019f4c80a0dd5854fa7670fb
Publikováno v:
mSphere, Vol 5, Iss 1 (2020)
ABSTRACT Candida albicans is an important human pathogen responsible for causing both superficial and systemic infections. Its ability to switch from the yeast form to the hyphal growth form is required for its pathogenicity. Acidic pH inhibits hypha
Externí odkaz:
https://doaj.org/article/4c036279cbde44d3a7b6570befdaa1c4
Autor:
Jiaxin Gao, Haitao Wang, Zeyao Li, Ada Hang-Heng Wong, Yi-Zheng Wang, Yahui Guo, Xin Lin, Guisheng Zeng, Haoping Liu, Yue Wang, Jianbin Wang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The fungal pathogen Candida albicans is diploid, which hinders genome-wide studies. Here, Gao et al. present a piggyBac transposon-mediated mutagenesis system using stable haploid C. albicans strains, and use it to identify genes and mechanisms under
Externí odkaz:
https://doaj.org/article/f9482aff0bce438592c86a1e3d00feb0
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT Candida albicans is the most common cause of invasive fungal infections in humans. Its ability to sense and adapt to changing carbon dioxide levels is crucial for its pathogenesis. Carbon dioxide promotes hyphal development. The hypha-specif
Externí odkaz:
https://doaj.org/article/df8a98c13a264c1b912927001b3d761a
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Many fungi are able to metabolise environmental N-acetylglucosamine, however the mechanism by which this molecule is sensed is unclear. Su and Lu et al. show that Candida albicansNGS1 fulfils this function by mediating N-acetylglucosamine-dependent h
Externí odkaz:
https://doaj.org/article/39f0b622e1ec47a6aa3d390cdd3c6262
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007176 (2018)
The pathogenic fungus Candida albicans can undergo phenotypic switching between two heritable states: white and opaque. This phenotypic plasticity facilitates its colonization in distinct host niches. The master regulator WOR1 is exclusively expresse
Externí odkaz:
https://doaj.org/article/2ac0d19474b041f4aa797a4f71fde555
Publikováno v:
PLoS Pathogens, Vol 8, Iss 4, p e1002663 (2012)
Candida albicans is an important opportunistic fungal pathogen of immunocompromised individuals. One critical virulence attribute is its morphogenetic plasticity. Hyphal development requires two temporally linked changes in promoter chromatin, which
Externí odkaz:
https://doaj.org/article/2c8710a2dfd84dd68c674f097695ec26
Publikováno v:
PLoS Biology, Vol 9, Iss 12 (2011)
Externí odkaz:
https://doaj.org/article/9a9fd898460744b5acc6e2fb60900bfd