Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Haopeng Yu"'
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 16, Pp 1912-1925 (2024)
Abstract. Biomolecular aggregation within cellular environments via liquid–liquid phase separation (LLPS) spontaneously forms droplet-like structures, which play pivotal roles in diverse biological processes. These structures are closely associated
Externí odkaz:
https://doaj.org/article/faef1cb021b549eda9a4aa08618c78ed
Autor:
Yueying Zhang, Qianli Dong, Zhen Wang, Qinzhe Liu, Haopeng Yu, Wenqing Sun, Jitender Cheema, Qiancheng You, Ling Ding, Xiaofeng Cao, Chuan He, Yiliang Ding, Huakun Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Plants, as sessile organisms, deploy transcriptional dynamics for adapting to extreme growth conditions such as cold stress. Emerging evidence suggests that chromatin architecture contributes to transcriptional regulation. However, the relat
Externí odkaz:
https://doaj.org/article/974491f2ee644387a5bd16cccf50c044
Autor:
Wei Xiao, Yi-long Chen, Long-yi Du, Jiqiu Wu, Zhang Wang, Bing Mao, Fu-qiang Wen, Peter Gerard Gibson, Vanessa M. McDonald, Haopeng Yu, Juan-juan Fu
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Rationale Our understanding of airway dysbiosis in chronic obstructive pulmonary disease (COPD) remains incomplete, which may be improved by unraveling the complexity in microbial interactome. Objectives To characterize reproducible features
Externí odkaz:
https://doaj.org/article/a1cdd1d421314ff697c8348ecc47c400
Autor:
Xiuxiao Tang, Pengguihang Zeng, Kezhi Liu, Li Qing, Yifei Sun, Xinyi Liu, Lizi Lu, Chao Wei, Jia Wang, Shaoshuai Jiang, Jun Sun, Wakam Chang, Haopeng Yu, Hebing Chen, Jiaguo Zhou, Chengfang Xu, Lili Fan, Yi-Liang Miao, Junjun Ding
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract CCCTC-binding factor (CTCF), a ubiquitously expressed and highly conserved protein, is known to play a critical role in chromatin structure. Post-translational modifications (PTMs) diversify the functions of protein to regulate numerous cell
Externí odkaz:
https://doaj.org/article/faa4b4d14dbe448096a8ea86944969cd
Autor:
Jun Sun, Jiale Qu, Cai Zhao, Xinyao Zhang, Xinyu Liu, Jia Wang, Chao Wei, Xinyi Liu, Mulan Wang, Pengguihang Zeng, Xiuxiao Tang, Xiaoru Ling, Li Qing, Shaoshuai Jiang, Jiahao Chen, Tara S. R. Chen, Yalan Kuang, Jinhang Gao, Xiaoxi Zeng, Dongfeng Huang, Yong Yuan, Lili Fan, Haopeng Yu, Junjun Ding
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Understanding intracellular phase separation is crucial for deciphering transcriptional control, cell fate transitions, and disease mechanisms. However, the key residues, which impact phase separation the most for protein phase separation fu
Externí odkaz:
https://doaj.org/article/e247857cd6f6444bb354b68e462cbba0
Autor:
Danni Cheng, Ke Qiu, Daibo Li, Minzi Mao, Yufang Rao, Yao Song, Lan Feng, Xiuli Shao, Chuanhuan Jiang, Yan Wang, Li Li, Xuemei Chen, Sisi Wu, Haiyang Wang, Jun Liu, Haopeng Yu, Wei Zhang, Fei Chen, Yu Zhao, Jianjun Ren
Publikováno v:
MedComm, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract Tumor‐infiltrating CD4+ T cells orchestrate the adaptive immune response through remarkable plasticity, and the expression patterns of exhaustion‐related inhibitory receptors in these cells differ significantly from those of CD8+ T cells
Externí odkaz:
https://doaj.org/article/3297f82bb8384ecaaebfb4fb0041d88d
Autor:
Yufang Rao, Ke Qiu, Yao Song, Minzi Mao, Lan Feng, Danni Cheng, Junhong Li, Ziyan Zhang, Yuyang Zhang, Xiuli Shao, Wendu Pang, Yan Wang, Xuemei Chen, Chuanhuan Jiang, Sisi Wu, Shuaishuai Yu, Jun Liu, Haiyang Wang, Xingchen Peng, Lin Yang, Li Chen, Xiaosong Mu, Yongbo Zheng, Wei Xu, Geoffrey Liu, Fei Chen, Haopeng Yu, Yu Zhao, Jianjun Ren
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109668- (2024)
Summary: Exhausted CD8+ T cells (Texs) are characterized by the expression of various inhibitory receptors (IRs), whereas the functional attributes of these co-expressed IRs remain limited. Here, we systematically characterized the diversity of IR co
Externí odkaz:
https://doaj.org/article/c15061f310b9456698f351b03789a7d4
Autor:
Xiaolei Liu, Jiqiu Wu, Jingyi Tang, Zhigang Xu, Bailing Zhou, Yang Liu, Fengjuan Hu, Gongchang Zhang, Rui Cheng, Xin Xia, Yilong Chen, Hongyu Wu, Daoming Wang, Jirong Yue, Biao Dong, Jingyuan Fu, Haopeng Yu, Birong Dong
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 5, Pp 2275-2288 (2023)
Abstract Background The gut microbiome and fecal metabolites have been found to influence sarcopenia, but whether there are potential bacteria that can alleviate sarcopenia has been under‐investigated, and the molecular mechanism remains unclear. M
Externí odkaz:
https://doaj.org/article/e6f90fceea1e4affb6895aa65a76b421
Autor:
Yilong Chen, Yalan Kuang, Siyuan Luan, Yongsan Yang, Zhiye Ying, Chunyang Li, Jinhang Gao, Yong Yuan, Haopeng Yu
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Esophageal carcinoma ranks as the sixth leading cause of cancer-related mortality globally, with esophageal squamous cell carcinoma (ESCC) being particularly prevalent among Asian populations. Alternative splicing (AS) plays a pivotal role in ESCC de
Externí odkaz:
https://doaj.org/article/6064fb8f8934418c8842932ff6aaa30b
Autor:
Zhihui Liu, Chenyang Lu, Pingying Qing, Ruijuan Cheng, Yujie Li, Xue Guo, Ye Chen, Zhiye Ying, Haopeng Yu, Yi Liu
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: The pathogenesis of common variable immunodeficiency disorder (CVID) is complex, especially when combined with autoimmunity. Genetic factors may be potential explanations for this complex situation, and whole genome sequencing (WGS) provi
Externí odkaz:
https://doaj.org/article/86ccfca07c5248929a435849ef0a1c4a