Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Haopeng, Xiao"'
Autor:
Pascal Devant, Elvira Boršić, Elsy M. Ngwa, Haopeng Xiao, Edward T. Chouchani, Jay R. Thiagarajah, Iva Hafner-Bratkovič, Charles L. Evavold, Jonathan C. Kagan
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 112008- (2023)
Summary: Reactive oxygen species (ROS) regulate the activities of inflammasomes, which are innate immune signaling organelles that induce pyroptosis. The mechanisms by which ROS control inflammasome activities are unclear and may be multifaceted. Her
Externí odkaz:
https://doaj.org/article/a61895e553eb4a44ae43092e7d90e406
Autor:
Weihai Liu, Yun Wang, Luiz H. M. Bozi, Patrick D. Fischer, Mark P. Jedrychowski, Haopeng Xiao, Tao Wu, Narek Darabedian, Xiadi He, Evanna L. Mills, Nils Burger, Sanghee Shin, Anita Reddy, Hans-Georg Sprenger, Nhien Tran, Sally Winther, Stephen M. Hinshaw, Jingnan Shen, Hyuk-Soo Seo, Kijun Song, Andrew Z. Xu, Luke Sebastian, Jean J. Zhao, Sirano Dhe-Paganon, Jianwei Che, Steven P. Gygi, Haribabu Arthanari, Edward T. Chouchani
Publikováno v:
Nature. 616:790-797
Autor:
Doan C. Nguyen, Swetha Garimalla, Haopeng Xiao, Shuya Kyu, Igor Albizua, Jacques Galipeau, Kuang-Yueh Chiang, Edmund K. Waller, Ronghu Wu, Greg Gibson, James Roberson, Frances E. Lund, Troy D. Randall, Iñaki Sanz, F. Eun-Hyung Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Antibody-secreting cells (ASC) such as plasma cells must migrate to the bone marrow to survive, but microniche elements that promote survival are unknown. Here the authors define specific factors from the microniche that can maintain ASC in vitro for
Externí odkaz:
https://doaj.org/article/8d6c5b762cbe4e5192797c6d2043c3fe
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Understanding the functions of protein glycosylation critically depends on methods to efficiently enrich glycoproteins from complex samples. Here, the authors develop a strategy using dendrimer-conjugated benzoboroxole to enhance glycopeptide enrichm
Externí odkaz:
https://doaj.org/article/003e950ab8cd4085b921ab58ee0f6809
Autor:
Mengnan Zhang, Lilya V. Matyunina, L. DeEtte Walker, Weixuan Chen, Haopeng Xiao, Benedict B. Benigno, Ronghu Wu, John F. McDonald
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract High-throughput technologies have identified significant changes in patterns of mRNA expression over cancer development but the functional significance of these changes often rests upon the assumption that observed changes in levels of mRNA
Externí odkaz:
https://doaj.org/article/7897ad282e104afabe0c3c6fd98e370c
Autor:
Doan C. Nguyen, Holly C. Lewis, Chester Joyner, Vivien Warren, Haopeng Xiao, Haydn T. Kissick, Ronghu Wu, Jacques Galipeau, F. Eun-Hyung Lee
Publikováno v:
Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)
Extracellular vesicles (EVs) from bone marrow (BM)-derived mesenchymal stromal cells (BM-MSC) are novel mechanisms of cell-cell communication over short and long distances. BM-MSC have been shown to support human antibody secreting cells (ASC) surviv
Externí odkaz:
https://doaj.org/article/ce20ad55404e4800851981a265d96979
Autor:
Anita Reddy, Sally Winther, Nhien Tran, Haopeng Xiao, Josefine Jakob, Ryan Garrity, Arianne Smith, Evanna L. Mills, Edward T. Chouchani
Publikováno v:
bioRxiv
Uptake of circulating succinate by brown adipose tissue (BAT) and beige fat elevates whole body energy expenditure, counteracts obesity, and antagonizes systemic tissue inflammation in mice. The plasma membrane transporters that facilitate succinate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04aba244e327aed2fe342901349dd1d
https://europepmc.org/articles/PMC10002717/
https://europepmc.org/articles/PMC10002717/
Autor:
Narek Darabedian, Wenzhi Ji, Mengyang Fan, Shan Lin, Hyuk-Soo Seo, Ekaterina V. Vinogradova, Tomer M. Yaron, Evanna L. Mills, Haopeng Xiao, Kristine Senkane, Emily M. Huntsman, Jared L. Johnson, Jianwei Che, Lewis C. Cantley, Benjamin F. Cravatt, Sirano Dhe-Paganon, Kimberly Stegmaier, Tinghu Zhang, Nathanael S. Gray, Edward T. Chouchani
Publikováno v:
Nature Chemical Biology.
Publikováno v:
Analytical Chemistry. 94:3343-3351
Glycoproteins with diverse glycans are essential to human cells, and subtle differences in glycan structures may result in entirely different functions. One typical example is proteins modified with O-linked β
Autor:
Austin Pan, Ruth T. Yu, Omer Keinan, Mikael Rydén, Christopher Liddle, Aldons J. Lusis, Julia H DeLuca, Benyamin Dadpey, Joseph M. Valentine, Michael Downes, Mohammad Abu-Odeh, Edward T. Chouchani, Markku Laakso, Sushil K. Mahata, Yang Dai, Shannon M. Reilly, Ronald M. Evans, Haopeng Xiao, Alan R. Saltiel, Leslie Cho
Publikováno v:
Nature, vol 599, iss 7884
Adipocytes increase energy expenditure in response to prolonged sympathetic activation via persistent expression of uncoupling protein 1 (UCP1)1,2. Here we report that the regulation of glycogen metabolism by catecholamines is critical for UCP1 expre