Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Haonan Lu"'
Autor:
Marianna Inglese, Neva Patel, Kristofer Linton-Reid, Flavia Loreto, Zarni Win, Richard J. Perry, Christopher Carswell, Matthew Grech-Sollars, William R. Crum, Haonan Lu, Paresh A. Malhotra, the Alzheimer’s Disease Neuroimaging Initiative, Eric O. Aboagye
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-16 (2022)
Inglese et al. develop a predictive model that computes multi-regional statistical morpho-functional mesoscopic traits from T1-weighted magnetic resonance imaging scans. Their model reliably discriminates people with Alzheimer’s disease-related pat
Externí odkaz:
https://doaj.org/article/516c8e439e694aad9272b31dd5159e63
Publikováno v:
Ultrasonics Sonochemistry, Vol 93, Iss , Pp 106289- (2023)
Currently, the polluted wastewater discharged by industry accounts for the major part of polluted bodies of water. As one of the industrial wastewaters, dye wastewater is characterized by high toxicity, wide pollution, and difficulty in decolorizatio
Externí odkaz:
https://doaj.org/article/15e1115e041e45269be6c7b302ac0257
Autor:
Haonan Lu, Jacob George, Mohammed Eslam, Augusto Villanueva, Luigi Bolondi, Helen L. Reeves, Misti McCain, Edward Chambers, Caroline Ward, Dewi Sartika, Caroline Sands, Lynn Maslen, Matthew R. Lewis, Ramya Ramaswami, Rohini Sharma
Publikováno v:
Liver Cancer (2022)
Objectives:The burden of metabolic (dysfunction) associated fatty liver disease (MAFLD) is rising mirrored by an increase in hepatocellular cancer (HCC). MAFLD and its sequelae are characterised by perturbations in lipid handling, inflammation and mi
Externí odkaz:
https://doaj.org/article/69273569903140508a4ccc2d6042c758
Autor:
Stefan Antonowicz, Zsolt Bodai, Tom Wiggins, Sheraz R. Markar, Piers R. Boshier, Yan Mei Goh, Mina E. Adam, Haonan Lu, Hiromi Kudo, Francesca Rosini, Robert Goldin, Daniela Moralli, Catherine M. Green, Chris J. Peters, Nagy Habib, Hani Gabra, Rebecca C. Fitzgerald, Zoltan Takats, George B. Hanna
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Volatile aldehydes can be enriched in esophageal adenocarcinoma patients’ breath. Here, the authors reveal corresponding metabolic changes in EAC tumours, which may be caused by impaired detoxification of endogenous metabolites.
Externí odkaz:
https://doaj.org/article/c4cb39fcd5d245a5814461336da92aeb
Publikováno v:
Sensors, Vol 23, Iss 1, p 264 (2022)
Very fast transient overvoltage (VFTO) generated by an operating disconnector is one of the main reasons for electromagnetic disturbance in gas-insulated switchgear (GIS) substations. Generally, the amplitude of VFTO can be used as one of the referen
Externí odkaz:
https://doaj.org/article/43aa24f269284a25bf50031f40d1a93b
Autor:
James R. Birtley, Mohammad Alomary, Elisa Zanini, Jane Antony, Zachary Maben, Grant C. Weaver, Claudia Von Arx, Manuela Mura, Aline T. Marinho, Haonan Lu, Eloise V. N. Morecroft, Evdoxia Karali, Naomi E. Chayen, Edward W. Tate, Mollie Jurewicz, Lawrence J. Stern, Chiara Recchi, Hani Gabra
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
OPCML is a tumour suppressor gene that is epigenetically silenced in ovarian cancer and is somatically mutated in various cancers. Here, the authors solve the X-ray crystal structure of OPCML and model clinically relevant mutations that could contrib
Externí odkaz:
https://doaj.org/article/0d39746c3dc44914b53cf2c2f0ee8062
Autor:
Haonan Lu, Mubarik Arshad, Andrew Thornton, Giacomo Avesani, Paula Cunnea, Ed Curry, Fahdi Kanavati, Jack Liang, Katherine Nixon, Sophie T. Williams, Mona Ali Hassan, David D. L. Bowtell, Hani Gabra, Christina Fotopoulou, Andrea Rockall, Eric O. Aboagye
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Radiomics—the quantification of features within tumor images—has shown prognostic potential in cancer. Here, the authors use a machine learning approach to develop a radiomic-based small set of descriptors to predict ovarian cancer patient surviv
Externí odkaz:
https://doaj.org/article/7fff94167bb54d9d9ccc2351fa73055a
Autor:
Paula Cunnea, Tommy Gorgy, Konstantinos Petkos, Sally A.N. Gowers, Haonan Lu, Cristina Morera, Wen Wu, Phillip Lawton, Katherine Nixon, Chi Leng Leong, Flavia Sorbi, Lavinia Domenici, Andrew Paterson, Ed Curry, Hani Gabra, Martyn G. Boutelle, Emmanuel M. Drakakis, Christina Fotopoulou
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Currently, there are no valid pre-operatively established biomarkers or algorithms that can accurately predict surgical and clinical outcome for patients with advanced epithelial ovarian cancer (EOC). In this study, we suggest that profiling
Externí odkaz:
https://doaj.org/article/cc3db571882b4b56b949edfb1aa0edd7
Autor:
Robert Brown, Sadaf Ghaem-Maghami, Marina Natoli, David J Pinato, John Gallon, Haonan Lu, Ala Amgheib, Francesco A Mauri, Teresa Marafioti, Ayse U Akarca, Ines Ullmo, Jacey Ip, Eric O Aboagye, Anastasios Karadimitris
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Background Endogenous retroviruses (ERVs) play a role in a variety of biological processes, including embryogenesis and cancer. DNA methyltransferase inhibitors (DNMTi)-induced ERV expression triggers interferon responses in ovarian cancer cells via
Externí odkaz:
https://doaj.org/article/7d3baf3de1394dd9863a83a84f696bd1
Autor:
Yunqing Li, Marianna Inglese, Suraiya Dubash, Chris Barnes, Diana Brickute, Marta Costa Braga, Ning Wang, Alice Beckley, Kathrin Heinzmann, Louis Allott, Haonan Lu, Cen Chen, Ruisi Fu, Laurence Carroll, Eric O. Aboagye
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1246 (2021)
Hypoxia is a complex microenvironmental condition known to regulate choline kinase α (CHKA) activity and choline transport through transcription factor hypoxia-inducible factor-1α (HIF-1α) and, therefore, may confound the uptake of choline radiotr
Externí odkaz:
https://doaj.org/article/d45310b8a4984fdbbf4cf37c689fdb94