Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Haohai Zhang"'
Autor:
Lili Feng, Haohai Zhang, Changchuin Mao, Paola de Andrade Mello, Dina Stroopinsky, Eva Csizmadia, Jialin Zhou, David Avigan, Jinming Yu, Wenda Gao, Simon C. Robson
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/a67922a3211e4d53855da2ccf91535cb
Genomic characterization and immunotherapy for microsatellite instability-high in cholangiocarcinoma
Autor:
Xu Yang, Baofeng Lian, Nan Zhang, Junyu Long, Yiran Li, Jingnan Xue, Xiangqi Chen, Yunchao Wang, Yanyu Wang, Ziyu Xun, Mingjian Piao, Chenpei Zhu, Shanshan Wang, Huishan Sun, Zhijian Song, Leilei Lu, Xiaowei Dong, Aodi Wang, Wenjin Liu, Jie Pan, Xiaorong Hou, Mei Guan, Li Huo, Jie Shi, Haohai Zhang, Jinxue Zhou, Zhenhui Lu, Yilei Mao, Xinting Sang, Liqun Wu, Xiaobo Yang, Kai Wang, Haitao Zhao
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Microsatellite instability-high (MSI-H) is a unique genomic status in many cancers. However, its role in the genomic features and immunotherapy in cholangiocarcinoma (CCA) is unclear. This study aimed to systematically investigate
Externí odkaz:
https://doaj.org/article/e96e78be7cfb426197e9dec8e4c18944
Autor:
Junyu Long, Dongxu Wang, Anqiang Wang, Peipei Chen, Yu Lin, Jin Bian, Xu Yang, Mingjun Zheng, Haohai Zhang, Yongchang Zheng, Xinting Sang, Haitao Zhao
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-21 (2022)
Abstract Background Immune checkpoint inhibitor (ICI) therapy has revolutionized the treatment of many cancers. However, the limited population that benefits from ICI therapy makes it necessary to screen predictive biomarkers for stratifying patients
Externí odkaz:
https://doaj.org/article/dd532aba6e274b6db4dc3fbf2187fb21
Autor:
Justin Mark Lunderberg, Sanjucta Dutta, Ai-Ris Y. Collier, Jeng-Shin Lee, Yen-Ming Hsu, Qiao Wang, Weina Zheng, Shushun Hao, Haohai Zhang, Lili Feng, Simon C. Robson, Wenda Gao, Stefan Riedel
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Despite the initially reported high efficacy of vaccines directed against ancestral SARS-CoV-2, repeated infections in both unvaccinated and vaccinated populations remain a major global health challenge. Because of mutation-mediated immune escape by
Externí odkaz:
https://doaj.org/article/b6df528c40e14dc090e41e973eb34f13
Autor:
Junyu Long, Dongxu Wang, Xu Yang, Anqiang Wang, Yu Lin, Mingjun Zheng, Haohai Zhang, Xinting Sang, Hanping Wang, Ke Hu, Haitao Zhao
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Immune checkpoint inhibitor (ICI) therapy elicits durable antitumor responses in patients with many types of cancer. Genomic mutations may be used to predict the clinical benefits of ICI therapy. NOTCH homolog-4 (NOTCH4) is freque
Externí odkaz:
https://doaj.org/article/3fc371a2dbd14100a7f23a790144a81c
Autor:
Haohai Zhang, Lili Feng, Paola de Andrade Mello, Changchuin Mao, Richard Near, Eva Csizmadia, Leo Li-Ying Chan, Keiichi Enjyoji, Wenda Gao, Haitao Zhao, Simon C. Robson
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 13 (2022)
Immunosuppressive cells accumulating in the tumor microenvironment constitute a formidable barrier that interferes with current immunotherapeutic approaches. A unifying feature of these tumor-associated immune and vascular endothelial cells appears t
Externí odkaz:
https://doaj.org/article/75dd513b812f4bd8b4022012fcf81fac
Publikováno v:
Automatika, Vol 62, Iss 1, Pp 44-54 (2021)
Early diagnosis of skin cancer from dermoscopy images significantly reduces the mortality due to this cancer. However, several reasons impact the system diagnosis precision. One of the important problems in this process happens during image acquisiti
Externí odkaz:
https://doaj.org/article/79ed0060c2494c9297c2f07ec7024365
Autor:
Rasika P. Harshe, Anyan Xie, Marta Vuerich, Luiza Abrahão Frank, Barbora Gromova, Haohai Zhang, Rene’ J. Robles, Samiran Mukherjee, Eva Csizmadia, Efi Kokkotou, Adam S. Cheifetz, Alan C. Moss, Satya K. Kota, Simon C. Robson, Maria Serena Longhi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
CD39 is an ectonucleotidase associated with immunoregulatory function. Here authors show regulation of CD39 expression by an endogenous antisense RNA moiety transcribed from the 3‘ end of CD39/ENTPD1 which when itself is silenced results in amelior
Externí odkaz:
https://doaj.org/article/53270d85737b4225a98e857f58c20b7a
Autor:
Junyu Long, Xu Yang, Jin Bian, Dongxu Wang, Anqiang Wang, Yu Lin, Mingjun Zheng, Haohai Zhang, Xinting Sang, Haitao Zhao
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 11, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/96b6a2e1ce744fbab61316cd9a77ffd1
Autor:
Anqiang Wang, Yu Lin, Haitao Zhao, Hanping Wang, Haohai Zhang, Junyu Long, Mingjun Zheng, Ke Hu, Xinting Sang, Xu Yang, Dongxu Wang
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
BMC Medicine
BMC Medicine
Background Immune checkpoint inhibitor (ICI) therapy elicits durable antitumor responses in patients with many types of cancer. Genomic mutations may be used to predict the clinical benefits of ICI therapy. NOTCH homolog-4 (NOTCH4) is frequently muta