Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Haofeng Zheng"'
Autor:
Yannan Zhang, Jiannan He, Zhe Yang, Haofeng Zheng, Haoxiang Deng, Zihuan Luo, Qipeng Sun, Qiquan Sun
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Immune-mediated rejection was the major cause of graft dysfunction. Although the advances in immunosuppressive agents have markedly reduced the incidence of T-cell-mediated rejection after transplantation. However, the incidence o
Externí odkaz:
https://doaj.org/article/ffcdb57655854ba49531392fc246f46a
Autor:
Zihuan Luo, Tao Liao, Yannan Zhang, Haofeng Zheng, Qipeng Sun, Fei Han, Maolin Ma, Yongrong Ye, Qiquan Sun
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 3, Pp n/a-n/a (2022)
Abstract Organ transplantation is the optimal treatment for patients with end‐stage diseases. T cell activation is a major contributing factor toward the trigger of rejection. Induction therapy with T cell depleting agent is a common option but inc
Externí odkaz:
https://doaj.org/article/5cd28daec46c404d86f5d5fb00a2faf3
Autor:
Yongrong Ye, Fei Han, Maolin Ma, Qipeng Sun, Zhengyu Huang, Haofeng Zheng, Zhe Yang, Zihuan Luo, Tao Liao, Heng Li, Liangqing Hong, Ning Na, Qiquan Sun
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: Delayed graft function (DGF) is a common complication after kidney transplantation (KT) with a poor clinical outcome. There are no accurate biomarkers for the early prediction of DGF. Macrophage migration inhibitory factor (MIF) release d
Externí odkaz:
https://doaj.org/article/0aaf14b63d714c27a8d014c0d110b090
Autor:
Tao Liao, Xiaonan Liu, Jie Ren, Hongjun Zhang, Haofeng Zheng, Xiujie Li, Yannan Zhang, Fei Han, Tinghui Yin, Qiquan Sun
Publikováno v:
EBioMedicine, Vol 37, Iss , Pp 236-245 (2018)
Background: C4d is a specific biomarker for the diagnosis of antibody-mediated rejection (AMR) after cardiac transplantation. Although strongly recommended, routine C4d surveillance is hindered by the invasive nature of endomyocardial biopsy. Targete
Externí odkaz:
https://doaj.org/article/224d617e2fd14a83ae43edd7505f5b86
Autor:
Haofeng Zheng, Yannan Zhang, Jiannan He, Zhe Yang, Rui Zhang, Lei Li, Zihuan Luo, Yongrong Ye, Qiquan Sun
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Chronic kidney disease (CKD), which is associated with high morbidity, remains a worldwide health concern, while effective therapies remain limited. Hydroxychloroquine (HCQ), which mainly targets toll-like receptor-7 (TLR-7) and TLR-9, is associated
Externí odkaz:
https://doaj.org/article/a3d590f2272f429f8b4ba7ebfc817dc9
Autor:
Haofeng Zheng, Yannan Zhang, Lei Li, Rui Zhang, Zihuan Luo, Zhe Yang, Yongrong Ye, Jiannan He, Qiquan Sun
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Toll-like receptor-9 (TLR-9) is a potent proinflammatory receptor that mediates renal injury. However, the reported effects of TLR-9 are contradictory. Here, using a traditional mouse AKI→CKD transition model, the roles of TLR-9 during the transiti
Externí odkaz:
https://doaj.org/article/5355e1f6587347ab992ef4e703358b63
Autor:
Zhe Yang, Fei Han, Tao Liao, Haofeng Zheng, Zihuan Luo, Maolin Ma, Jiannan He, Lei Li, Yongrong Ye, Rui Zhang, Zhengyu Huang, Yannan Zhang, Qiquan Sun
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Immunological rejection is an important factor resulting in allograft dysfunction, and more valid therapeutic methods need to be explored to improve allograft outcomes. Many researches have indicated that artemisinin and its derivative exhibits immun
Externí odkaz:
https://doaj.org/article/f3a108497dc646bba2da2396cf81c0ab
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Transplant vasculopathy (TV), a hallmark of chronic allograft rejection, is the primary cause of allograft loss after organ transplantation. Because multiple mechanisms are involved in TV pathogenesis, effective therapy for it remains elusive. Here,
Externí odkaz:
https://doaj.org/article/c80c50f6ca1740ea814c21a145c57156
Autor:
Daqiang Zhao, Tao Liao, Siwen Li, Yannan Zhang, Haofeng Zheng, Jing Zhou, Fei Han, Yu Dong, Qiquan Sun
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Antibody-mediated rejection (AMR) is the main barrier to renal graft survival, and mouse renal AMR models are important to study this process. Current mouse models are established by priming the recipient to donor skin for over 7 days before kidney t
Externí odkaz:
https://doaj.org/article/3b4bd71d95ad415481a2910bdb6d0b24
Autor:
Tao Liao, Youqiu Xue, Daqiang Zhao, Siwen Li, Mingyu Liu, Jingrong Chen, David Douglass Brand, Haofeng Zheng, Yannan Zhang, Song Guo Zheng, Qiquan Sun
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Antibody-mediated rejection (AMR) has emerged as the major cause of renal allograft dysfunction, and more effective strategies need to be explored for improving transplant outcomes. Regulatory T cells (Tregs), consisting of at least natural and induc
Externí odkaz:
https://doaj.org/article/a2e9a803ade441e6a6a629468b129254