Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Haofei Qi"'
Publikováno v:
Journal of Heterocyclic Chemistry. 52:1565-1569
An efficient synthetic method for the pemetrexed disodium has been developed using methyl 4-iodobenzoate and 3-buten-1-ol as starting materials via six steps. The developed process avoided some tedious workup procedures and unfriendly reagents compar
Publikováno v:
Journal of Heterocyclic Chemistry. 52:1212-1218
A series of pyridine Rho kinase inhibitors were designed and synthesized utilizing the ligand-binding pocket model with Y-26732 as the lead compound. These compounds were evaluated on cell lines for their biological activities.
Publikováno v:
Research on Chemical Intermediates. 39:3111-3115
An impurity was isolated from crude synthesized roflumilast and characterized by 1H NMR, 13C NMR, and HR-MS, which confirmed the structure as N-(3,5-dichloropyrid-4-yl)-4-difluoromethoxy-3-hydroxybenzamide. To further verify the structure, this compo
Publikováno v:
Asian Journal of Chemistry. 26:7226-7228
Publikováno v:
ChemInform. 45
A simple and efficient method for the hydroarylation of various electron-rich arenes and styrenes using the sulfonic acidic resin D072 as a green and heterogeneous catalyst is developed.
A series of acidic cation-exchange resins were used for the hydroarylation of resorcinol with styrene, in which resin D072 exhibited the excellent catalytic performance in this reaction with 99% conversion of styrene and 90% selectivity of 4-(1-pheny
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7822bacde1144badeeb69438f4bb5ed1
A series of acidic cation-exchange resins were used for the hydroalkylation of resorcinol with styrene, in which resin D072 exhibited the excellent catalytic performance in this reaction with 99% conversion of styrene and 90% selectivity of 4-(1-phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8aef801f78e4af7859abc7e10cddd691
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(4)
A series of novel pazopanib derivatives, 7a–m, were designed and synthesized by modification of terminal benzene and indazole rings in pazopanib. The structures of all the synthesized compounds were confirmed by 1H NMR and MS. Their inhibitory acti
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 11, Pp o2955-o2955 (2010)
Acta Crystallographica Section E: Structure Reports
Acta Crystallographica Section E: Structure Reports
In the title compound, C13H12ClN5, which is a derivative of the antitumor agent pazopanib {systematic name: 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzolsulfonamide}, the indazole and pyrimidine fragments form