Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Haobo Jiang"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Insect phenoloxidases (POs) catalyze phenol oxygenation and o-diphenol oxidation to form reactive intermediates that kill invading pathogens and form melanin polymers. To reduce their toxicity to host cells, POs are produced as prophenoloxidases (PPO
Externí odkaz:
https://doaj.org/article/6d18a6ad30f64c5d9e4b4a6cd5c2a295
Publikováno v:
Journal of Innate Immunity, Pp 1-15 (2022)
The melanization and Toll pathways, regulated by a network of serine proteases and noncatalytic serine protease homologs (SPHs), have been investigated mostly in adult and larval insects. However, how these innate immune reactions are regulated in in
Externí odkaz:
https://doaj.org/article/9664e0274e404f758922dcd07e3f22b7
Autor:
Mengyi Yin, Wenhua Kuang, Qianran Wang, Xi Wang, Chuanfei Yuan, Zhe Lin, Huanyu Zhang, Fei Deng, Haobo Jiang, Peng Gong, Zhen Zou, Zhihong Hu, Manli Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Poxins or P26 have been identified as inhibitors of cGAS-STING mediated innate immunity. Here, the authors describe an independently evolved antiviral function of P26 in suppressing melanization, an insect immune response.
Externí odkaz:
https://doaj.org/article/27f6c3d006374a15905c1dede99eb25a
Autor:
Haili Li, Haobo Jiang, Jingye Wang, Jin Zhou, Hao Liang, Guangxue Chen, Zehua Guo, Shaofeng Yang, Yonghui Zhang
Publikováno v:
Geriatric Orthopaedic Surgery & Rehabilitation, Vol 14 (2023)
Introduction Osteoporosis is a major cause of fractures and even life-threatening fractures in the elderly. Mind-body exercise is a beneficial intervention to improve flexibility, control body balance and reduce pain. We aimed to evaluate the effects
Externí odkaz:
https://doaj.org/article/5db8f4a1bc40433988f1830c43a377f3
Nitric Oxide-Induced Calcineurin A Mediates Antimicrobial Peptide Production Through the IMD Pathway
Autor:
Kangkang Chen, Xinyan Wang, Xiangyi Wei, Jiaqian Chen, Youheng Wei, Haobo Jiang, Zhiqiang Lu, Congjing Feng
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Nitric oxide (NO) at a high concentration is an effector to kill pathogens during insect immune responses, it also functions as a second messenger at a low concentration to regulate antimicrobial peptide (AMP) production in insects. Drosophila calcin
Externí odkaz:
https://doaj.org/article/4850293394604135a9bf9b4c24a7dd73
Autor:
Xiaolong Cao, Haobo Jiang
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background Manduca sexta is a large lepidopteran insect widely used as a model to study biochemistry of insect physiological processes. As a part of its genome project, over 50 cDNA libraries have been analyzed to profile gene expression in
Externí odkaz:
https://doaj.org/article/de28fed92e034377931ede8707648202
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89473 (2014)
Antimalarial drugs may impact mosquito's defense against Plasmodium parasites. Our previous study showed nitroquine significantly reduced infection of Anopheles stephensi by Plasmodium yoelii, but the underlying mechanism remains unclear. In order to
Externí odkaz:
https://doaj.org/article/58097ef633a242029d4f07e876cf8881
Publikováno v:
International Journal of Refrigeration. 146:390-402
Publikováno v:
Insect Science. 30:338-350
Serine esterases (SEs) are hydrolases that catalyze the conversion of carboxylic esters into acids and alcohols. Lipases and carboxylesterases constitute two major groups of SEs. Although over a hundred of insect genomes are known, systematic identif
Publikováno v:
IEEE Transactions on Neural Networks and Learning Systems. :1-11
Double Q-learning is a popular reinforcement learning algorithm in Markov decision process (MDP) problems. Clipped double Q-learning, as an effective variant of double Q-learning, employs the clipped double estimator to approximate the maximum expect