Hydroamination of Unactivated Alkenes with Aliphatic Azides

Autor: Si-Ming Jia, Yi-Hang Huang, Zhan-Lin Wang, Fang-Xu Fan, Bo-Han Fan, Hao-Xiang Sun, Hao Wang, Fei Wang

Publikováno v: Journal of the American Chemical Society. 144:16316-16324

We report here an efficient and highly diastereoselective intermolecular anti-Markovnikov hydroamination of unactivated alkenes with aliphatic azides in the presence of silane. The system tolerates a wide range of azides and alkenes and operates with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d7c0b51f73ab04b2a12c2519925e1f3
https://doi.org/10.1021/jacs.2c07643

Prevalence and genetic–phenotypic characteristics of patients with USH2A mutations in a large cohort of Chinese patients with inherited retinal disease

Autor: Ping Xu, Fang Chen, Qing Chang, Dan-Dan Wang, Fang-Yuan Hu, Yu-He Qi, Wei Liu, Hao-Xiang Sun, Feng-Juan Gao, Shenghai Zhang, Jihong Wu, Wei Li, Ming Wang, Gezhi Xu, Jiankang Li

Publikováno v: The British Journal of Ophthalmology
Gao, F-J, Wang, D-D, Chen, F, Sun, H-X, Hu, F-Y, Xu, P, Li, J, Liu, W, Qi, Y-H, Li, W, Wang, M, Zhang, S, Xu, G-Z, Chang, Q & Wu, J-H 2021, ' Prevalence and genetic-phenotypic characteristics of patients with USH2A mutations in a large cohort of Chinese patients with inherited retinal disease ', British Journal of Ophthalmology, vol. 105, no. 1, pp. 87-92 . https://doi.org/10.1136/bjophthalmol-2020-315878

AimsTo investigate the frequency of USH2A mutation and the clinical and genetic differences between Usher syndrome type II (USH2) and retinitis pigmentosa (RP) in a large cohort of Chinese patients.MethodsA total of 1381 patients with inherited retin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b8c614ffbc880a9f98c370e100950b
http://europepmc.org/articles/PMC7788223

A Phenotype-Specific Framework for Identifying the Eye Abnormalities Causative Nonsynonymous-Variants

Autor: Chang-Geng Tian, Hao-Xiang Sun, Shenghai Zhang, Fang Chen, Chen Ye, Hankui Liu, Xiao Dang, Jihong Wu, Liping Guan, Laurent C. A. M. Tellier, Jianguo Zhang, Huanming Yang

Publikováno v: SSRN Electronic Journal.

The most important role of variant pathogenicity predictors is to identify the disease-phenotype causative variant in studying monogenic diseases. In the last decade, machine-learning based predictors exhibited a relatively accurate performance for d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21493efa38dabf6342563c45e5dba48d
https://doi.org/10.2139/ssrn.3586993

Method and Research on Detecting Unknown Frequency Signal in Duffing Oscillator Detection Blind Zone

Autor: Yun-fei Ling, Hao-xiang Sun, Xiang-yang Lin, Chang-xing Chen, Ji-yao Huang

Publikováno v: Journal of Physics: Conference Series. 1213:052064

In view of the problem of blind area in detecting weak iso-frequency signals of Duffing oscillator, an anova technique is proposed to detect the signal in blind area.By analyzing the condition of detecting blind area, the range of phase of the signal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::266beee4d11caa56fe157bb599659518
https://doi.org/10.1088/1742-6596/1213/5/052064

Method and Research on Detecting Unknown Frequency Signal in Duffing Oscillator Detection Blind Zone.

Autor: Ji-yao Huang, Chang-xing Chen, Yun-fei Ling, Xiang-yang Lin, Hao-xiang Sun

Publikováno v: Journal of Physics: Conference Series; 2019, Vol. 1213 Issue 5, p1-1, 1p