Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Hao-Yang Yuan"'
BOD1 regulates the cerebellar IV/V lobe-fastigial nucleus circuit associated with motor coordination
Autor:
Xiu-Xiu Liu, Xing-Hui Chen, Zhi-Wei Zheng, Qin Jiang, Chen Li, Lin Yang, Xiang Chen, Xing-Feng Mao, Hao-Yang Yuan, Li-Li Feng, Quan Jiang, Wei-Xing Shi, Takuya Sasaki, Kohji Fukunaga, Zhong Chen, Feng Han, Ying-Mei Lu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-14 (2022)
Abstract Cerebellar ataxias are characterized by a progressive decline in motor coordination, but the specific output circuits and underlying pathological mechanism remain poorly understood. Through cell-type-specific manipulations, we discovered a n
Externí odkaz:
https://doaj.org/article/7040bb88fa0149eea18a0a6f48fb8c9c
Autor:
Chu Tong, Peng-Xiang Min, Qian Zhang, Ru-Xin Gu, Yao-Hai Wen, Yi Shi, Yu-Huan Bao, Xiang Chen, Yi-Xuan Zhang, Xing-Feng Mao, Hao-Yang Yuan, Xiu-Xiu Liu, Takuya Sasaki, Li Zhang, Feng Han, Ying-Mei Lu
Publikováno v:
Research, Vol 6 (2023)
Disturbance of the cholinergic system plays a crucial role in the pathological progression of neurological diseases that cause dyskinesia-like behaviors. However, the molecular mechanisms underlying this disturbance remain elusive. Here, we showed th
Externí odkaz:
https://doaj.org/article/b3b1451bff8d48469b3f4c8da9f393da
Autor:
Chao Li, Yang-yang He, Yu-ting Zhang, Yi-chuan You, Hao-yang Yuan, Yun-geng Wei, Xi Chen, Jie Chen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 151, Iss , Pp 113173- (2022)
Exposure to crystalline silica (CS) results in a persistent pulmonary inflammatory response, which results in abnormal tissue repair and excessive matrix deposition. Due to vague pathogenesis, there is virtually no practical therapeutic approach. Her
Externí odkaz:
https://doaj.org/article/4c653441cb214e8a89c4944c614b2de9
Autor:
Yi-Fan Luo, Lu Lu, Heng-Yi Song, Han Xu, Zhi-Wei Zheng, Zhou-Yue Wu, Chen-Chen Jiang, Chu Tong, Hao-Yang Yuan, Xiu-Xiu Liu, Xiang Chen, Mei-ling Sun, Ya-Min Tang, Heng-Yu Fan, Feng Han, Ying-Mei Lu
Publikováno v:
Molecular Psychiatry.
The comorbidity of autism spectrum disorder and anxiety is common, but the underlying circuitry is poorly understood. Here, Tmem74-/- mice showed autism- and anxiety-like behaviors along with increased excitability of pyramidal neurons (PNs) in the p
Autor:
Daming Zuo, Yu Chen, Jian-piao Cai, Hao-Yang Yuan, Jun-Qi Wu, Yue Yin, Jing-Wen Xie, Jing-Min Lin, Jia Luo, Yang Feng, Long-Jiao Ge, Jia Zhou, Ronald J Quinn, San-Jun Zhao, Xing Tong, Dong-Yan Jin, Shuofeng Yuan, Shao-Xing Dai, Min Xu
Publikováno v:
Protein & Cell.
The twenty-first century has already recorded more than ten major epidemics or pandemics of viral disease, including the devastating COVID-19. Novel effective antivirals with broad-spectrum coverage are urgently needed. Herein, we reported a novel br
Publikováno v:
Bioorganicmedicinal chemistry letters. 42
A pair of stereoisomers of new 4,5-dihydroxypiperine was isolated from P. retrofractum and showed profound activity on AlCl
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 42:128057
A pair of stereoisomers of new 4,5-dihydroxypiperine was isolated from P. retrofractum and showed profound activity on AlCl3-induced dementia. In order to determine their absolute configurations and biological activities, all four possible stereoisom
Autor:
Hai-Zhou Li, Chong-Ren Yang, Da-Min Zuo, Kong Yang, Ying-Jun Zhan, Ai-Ping Yin, Hao-Yang Yuan, Chen Gu, Xu Min, Jia Luo
Publikováno v:
Fitoterapia. 137:104151
The norbisabolane-type sesquiterpenoids bearing a spiroketal functionality have been found in Phyllanthus spp. and showed anti-HBV activities. As part of an ongoing effort to search for promising anti-HBV sesquiterpenes from Phyllanthus plants, we re
Publikováno v:
Natural Product Communications. 12:1934578X1701201
The genus Gentiana is one of the largest genera in the Gentianaceae family. Many Gentiana species have been scientifically investigated for their chemical constituents and chemotaxonomic sense. To date, more than 500 chemical compounds were isolated
Autor:
Yang, Hao1 (AUTHOR), Yang, Yuan1 (AUTHOR), Kiskin, Fedir N.1 (AUTHOR), Shen, Mengcheng2 (AUTHOR), Zhang, Joe Z.1 (AUTHOR) joezhang@szbl.ac.cn
Publikováno v:
Stem Cell Research & Therapy. 8/30/2023, Vol. 14 Issue 1, p1-17. 17p.