Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hao-Lun Chen"'
Autor:
Zhao-Da Duan, Li-Yang Zheng, Qiu-Ye Jia, Hao-Lun Chen, Dong-Yao Xu, Yu-Jia Yang, Zhi Qi, Li Yang, Chun-Yun Wu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Previous studies have shown that scutellarin inhibits the excessive activation of microglia, reduces neuronal apoptosis, and exerts neuroprotective effects. However, whether scutellarin regulates activated microglia-mediated neuronal apoptos
Externí odkaz:
https://doaj.org/article/484392d96b504a778b3704c4266659c9
Autor:
Qiu-Ye Jia, Hao‑Lun Chen, Zhi Qi, Xiao‑Li‑Na Zhang, Li-Yang Zheng, Teng-Teng Liu, Yun Yuan, Li Yang, Chun‑Yun Wu
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Scutellarin is used to treat brain ischaemia. However, its underlying mechanism of action remains unclear. This study aimed to elucidate the potential mechanism of action of scutellarin in brain ischaemia through network pharmacology and exp
Externí odkaz:
https://doaj.org/article/d3858dc20b8845adaed965b497e71122
Autor:
Hao-Lun Chen, 陳皓倫
97
Metabolic syndromes, cardiovascular diseases and diabetic atherosclerosis have common risk factors such as insulin resistance, obesity, and hypertension. However, diabetic atherosclerosis solely manifests endothelial dysfunction, lipid and li
Metabolic syndromes, cardiovascular diseases and diabetic atherosclerosis have common risk factors such as insulin resistance, obesity, and hypertension. However, diabetic atherosclerosis solely manifests endothelial dysfunction, lipid and li
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/61956467790547779076
Autor:
Hao-Lun Chen, Li Yang, Xiao-Li-Na Zhang, Qiu-Ye Jia, Zhao-Da Duan, Juan-juan Li, Li-yang Zheng, Teng-teng Liu, Zhi Qi, Yun Yuan, Chun-Yun Wu
Publikováno v:
Molecular Neurobiology.
Autor:
Qiu-Ye Jia, Hao‑Lun Chen, Zhi Qi, Xiao‑Li‑Na Zhang, Li-Yang Zheng, Teng-Teng Liu, Yun Yuan, Li Yang, Chun‑Yun Wu
Objective This study elucidated the neuroprotective mechanisms of scutellarin in microglia and astrocytes during the progression of neuropathology in cerebral ischemia. Methods Network pharmacology was first used to filtrate the core targets and path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73d9660e67cc266960caaeb428a1c2ba
https://doi.org/10.21203/rs.3.rs-2175892/v1
https://doi.org/10.21203/rs.3.rs-2175892/v1
Autor:
Chunyun Wu, Hao-Lun Chen, Hong-E Li, Hong Han, Yun Yuan, Xiao-Li-Na Zhang, Wen-Ji Jia, Fan Li, Juan-Juan Li
Publikováno v:
Neuromolecular medicine. 22(2)
Scutellarin, an herbal compound, can effectively suppress the inflammatory response in activated microglia/brain macrophage(AM/BM) in experimentally induced cerebral ischemia; however, the underlying mechanism for this has not been fully clarified. W