Pembrolizumab activity in patients with Fanconi anemia repair pathway competent and deficient tumors

Autor: Miguel A. Villalona-Calero, John P. Diaz, Wenrui Duan, Zuanel Diaz, Eric D. Schroeder, Santiago Aparo, Troy Gatcliffe, Federico Albrecht, Siddhartha Venkatappa, Victor Guardiola, Sara Garrido, Muni Rubens, Fernando DeZarraga, Hao Vuong

Publikováno v: Biomarker Research, Vol 10, Iss 1, Pp 1-11 (2022)

Abstract Background Given the observed antitumor activity of immune-checkpoint-inhibitors in patients with mismatch-repair deficient (MSI-H) tumors, we hypothesized that deficiency in homologous-recombination-repair (HRR) can also influence susceptib

Externí odkaz: https://doaj.org/article/638687a2c44a4b188f5880b1264f5ad8

Real-world analysis of afatinib as a first-line treatment for patients with advanced stage non-small-cell lung cancer with uncommon EGFR mutations: a multicenter study in Vietnam

Autor: Van Luan Pham, Tuan Anh Le, Cam Phuong Pham, Thi Thai Hoa Nguyen, Anh Tu Do, Tuan Khoi Nguyen, Minh Hai Nguyen, Thi Anh Thu Hoang, Dinh Thy Hao Vuong, Dac Nhan Tam Nguyen, Van Khiem Dang, Thi Oanh Nguyen, Thi Huyen Trang Vo, Hung Kien Do, Ha Thanh Vu, Thi Thuy Hang Nguyen, Van Thai Pham, Le Huy Trinh, Khac Dung Nguyen, Hoang Gia Nguyen, Cong Minh Truong, Tran Minh Chau Pham, Thi Bich Phuong Nguyen

Publikováno v: Therapeutic Advances in Medical Oncology, Vol 16 (2024)

Background: Afatinib is indicated for advanced-stage non-small-cell lung cancer (NSCLC) with Epidermal Growth Factor Receptor (EGFR) and uncommon mutations. However, real-world studies on this topic are limited. This study aimed to evaluate afatinib

Externí odkaz: https://doaj.org/article/3b242dda304e403081168f58d3efed5e

Body image in and out of the lab: Correspondence between lab-based attentional bias data and body shape dissatisfaction experiences in daily life

Autor: Hao Vuong, Jaclyn Broadbent, Jake Linardon, Rachel F. Rodgers, Matthew Fuller-Tyszkiewicz, Isabel Krug

Publikováno v: Body Image. 32:62-69

Accumulating lab-based studies have identified attentional biases in processing of negative appearance-related information among individuals with elevated trait body shape and weight dissatisfaction (BD). How these biases translate into experiences o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1d6b51376b0debfc25bcb48bb7fbf6
https://doi.org/10.1016/j.bodyim.2019.11.002

Assessment of the Fanconi anemia repair pathway as a predictor of clinical activity of pembrolizumab (PEM)

Autor: Siddhartha A. Venkatappa, John Paul Diaz, Gail Walker, Zuanel Diaz, Alfredo Pedro Alonso, Miguel A. Villalona-Calero, Santiago Aparo, Muni Rubens, Sara M. Garrido, Sebastian Cuitiva, Hao Vuong, Eric Schroeder, Wenrui Duan, Federico Albrecht, Victor Guardiola, Michael B. Troner, Fernando I. De Zarraga, Troy Antony Gatcliffe

Publikováno v: Journal of Clinical Oncology. 37:2555-2555

2555 Background: Given the activity of immune checkpoint inhibitors (ICI) in mismatch repair deficient tumors, we evaluated if homologous recombination repair deficiency associates with solid tumor response to ICI. Methods: We conducted a phase 2 tri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb1a0903adfba38a8d18109fec026937
https://doi.org/10.1200/jco.2019.37.15_suppl.2555

FOLFOXIRI for First-Line Treatment of Unresectable Colorectal Cancer with Liver Metastases in a Resource-Limited Setting.

Autor: Hao VDT; Chemotherapy Department, Cancer Center, Cho Ray Hospital, Ho Chi Minh City, Vietnam., Tri PM; Department of General Surgery, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.; Hepato-Pancreato-Biliary Surgery Department, Cho Ray Hospital, Ho Chi Minh City, Vietnam., My DT; Hepato-Pancreato-Biliary Surgery Department, Cho Ray Hospital, Ho Chi Minh City, Vietnam., Anh LT; Chemotherapy Department, Cancer Center, Cho Ray Hospital, Ho Chi Minh City, Vietnam., Trung LV; Department of General Surgery, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.; Digestive Surgery Department, Cho Ray Hospital, Ho Chi Minh City, Vietnam., Bac NH; Department of General Surgery, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.; Gastro-Intestinal Surgery Department, University Medical Center, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam., Vuong NL; Department of Medical Statistics and Informatics, Faculty of Public Health, University of Medicine and Pharmacy at Ho Chi Minh City, 217 Hong Bang, Ward 11, District 5, Ho Chi Minh City, Vietnam. nguyenlamvuong@ump.edu.vn.

Publikováno v: Journal of gastrointestinal cancer [J Gastrointest Cancer] 2024 Oct 31; Vol. 56 (1), pp. 12. Date of Electronic Publication: 2024 Oct 31.