Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Hao Long Dong"'
Autor:
Yuan-yuan Lu, Yi Li, Zhi-li Chen, Xiang-hua Xiong, Qing-yang Wang, Hao-long Dong, Chen Zhu, Jia-zhen Cui, Ao Hu, Lei Wang, Na Song, Gang Liu, Hui-peng Chen
Publikováno v:
Molecular and Cellular Probes, Vol 77, Iss , Pp 101981- (2024)
The clinical treatment of hepatocellular carcinoma (HCC) is still a heavy burden worldwide. Intracellular microRNAs (miRNAs) commonly express abnormally in cancers, thus they are potential therapeutic targets for cancer treatment. miR-21 is upregulat
Externí odkaz:
https://doaj.org/article/c6d4e820ff6949e2ab4dff7f827be63c
Autor:
Yu-Zhong Feng, Hao Cheng, Guo-Qing Xiong, Jia-Zhen Cui, Zhi-Li Chen, Yuan-Yuan Lu, Zhi-Xin Meng, Chen Zhu, Hao-Long Dong, Xiang-Hua Xiong, Gang Liu, Qing-Yang Wang, Hui-Peng Chen
Publikováno v:
Biomedicines, Vol 12, Iss 11, p 2602 (2024)
Background: Uricase, or urate oxidase (Uox) is a key enzyme in uric acid (UA) metabolism and has been applied in clinical treatment of human hyperuricemia (HUA). However, the current clinically applied uricases, despite their potent urate-lowering ca
Externí odkaz:
https://doaj.org/article/0af7a33bad0d416f9938b4d4f3715073
Autor:
Hao-Long Dong, Zhi-Li Chen, Mei-Juan He, Jia-Zhen Cui, Hao Cheng, Qing-Yang Wang, Xiang-Hua Xiong, Gang Liu, Hui-Peng Chen
Publikováno v:
Vaccines, Vol 12, Iss 2, p 215 (2024)
Zika virus (ZIKV) is an emerging flavivirus that causes congenital syndromes including microcephaly and fetal demise in pregnant women. No commercial vaccines against ZIKV are currently available. We previously generated a chimeric ZIKV (ChinZIKV) ba
Externí odkaz:
https://doaj.org/article/ef0cc7d10ba545c6910e3a88fb562376
Autor:
Hao-Long Dong, Mei-Juan He, Qing-Yang Wang, Jia-Zhen Cui, Zhi-Li Chen, Xiang-Hua Xiong, Lian-Cheng Zhang, Hao Cheng, Guo-Qing Xiong, Ao Hu, Yuan-Yuan Lu, Chun-Lin Cheng, Zhi-Xin Meng, Chen Zhu, Guang Zhao, Gang Liu, Hui-Peng Chen
Publikováno v:
Vaccines, Vol 11, Iss 7, p 1250 (2023)
The genus Flavivirus is a group of arthropod-borne single-stranded RNA viruses, which includes important human and animal pathogens such as Japanese encephalitis virus (JEV), Zika virus (ZIKV), Dengue virus (DENV), yellow fever virus (YFV), West Nile
Externí odkaz:
https://doaj.org/article/baffd40e9be54a8587299d653a03a8c4
Autor:
Hao-Long Dong, Hong-Jiang Wang, Zhong-Yu Liu, Qing Ye, Xiao-Ling Qin, Dan Li, Yong-Qiang Deng, Tao Jiang, Xiao-Feng Li, Cheng-Feng Qin
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 1739-1750 (2021)
Yellow fever virus (YFV) is a re-emerging flavivirus, which can lead to severe clinical manifestations and high mortality, with no specific antiviral therapies available. The live-attenuated yellow fever vaccine 17D (YF17D) has been widely used for o
Externí odkaz:
https://doaj.org/article/63228352def14e168a499a1fb76d917d
Autor:
Hong-Lei Zhang, Hao-Long Dong, Ya-Nan Zhang, Lin-Lin Xu, Cheng-Lin Deng, Xiao-Feng Li, Xiao-Dan Li, Han-Qing Ye, Zhi-Ming Yuan, Cheng-Feng Qin, Bo Zhang
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 1574-1583 (2019)
ABSTRACTChikungunya virus (CHIKV), a mosquito-borne alphavirus, has become an important re-emerging pathogen with its rapid spread to many non-endemic areas. The lack of effective vaccines and antiviral agents is largely attributed to the elusive inf
Externí odkaz:
https://doaj.org/article/b2f637c5714143a5856899c95132b6f6
Autor:
Chunfeng Li, Yong-Qiang Deng, Shulong Zu, Natalie Quanquin, Jingzhe Shang, Min Tian, Xue Ji, Na-Na Zhang, Hao-Long Dong, Yan-Peng Xu, Ling-Zhai Zhao, Fu-Chun Zhang, Xiao-Feng Li, Aiping Wu, Genhong Cheng, Cheng-Feng Qin
Publikováno v:
Emerging Microbes and Infections, Vol 7, Iss 1, Pp 1-10 (2018)
Abstract Zika virus (ZIKV) has elicited global concern due to its unique biological features, unusual transmission routes, and unexpected clinical outcomes. Although ZIKV transmission through anal intercourse has been reported in humans, it remains u
Externí odkaz:
https://doaj.org/article/61cd5f9fc91d452db30fadbc232efa4f
Autor:
Xiao-Feng Li, Hao-Long Dong, Hong-Jiang Wang, Xing-Yao Huang, Ye-Feng Qiu, Xue Ji, Qing Ye, Chunfeng Li, Yang Liu, Yong-Qiang Deng, Tao Jiang, Gong Cheng, Fu-Chun Zhang, Andrew D. Davidson, Ya-Jun Song, Pei-Yong Shi, Cheng-Feng Qin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Given the recent Zika virus (ZIKV) epidemic, development of an effective vaccine is of high importance. Here, the authors use a licensed live-attenuated flavivirus vaccine backbone to develop a ZIKV vaccine and determine immunogenicity, safety and pr
Externí odkaz:
https://doaj.org/article/788df413c3c54bebaab8d4b979a10833
Autor:
Yong-Qiang Deng, Na-Na Zhang, Xiao-Feng Li, Ya-Qing Wang, Min Tian, Ye-Feng Qiu, Jun-Wan Fan, Jia-Nan Hao, Xing-Yao Huang, Hao-Long Dong, Hang Fan, Yu-Guang Wang, Fu-Chun Zhang, Yi-Gang Tong, Zhiheng Xu, Cheng-Feng Qin
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Human case studies suggest that Zika virus can be transmitted independently of mosquitoes and sexual contact. Here, the authors show intranasal Zika infection in different animal models and show that contact transmission of Zika virus occurs in guine
Externí odkaz:
https://doaj.org/article/40e389e7970a459ba89c835d385e7af5
Autor:
Xiao-Feng Li, Hao-Long Dong, Xing-Yao Huang, Ye-Feng Qiu, Hong-Jiang Wang, Yong-Qiang Deng, Na-Na Zhang, Qing Ye, Hui Zhao, Zhong-Yu Liu, Hang Fan, Xiao-Ping An, Shi-Hui Sun, Bo Gao, Yun-Zhi Fa, Yi-Gang Tong, Fu-Chun Zhang, George F. Gao, Wu-Chun Cao, Pei-Yong Shi, Cheng-Feng Qin
Publikováno v:
EBioMedicine, Vol 12, Iss C, Pp 170-177 (2016)
Animal models are critical to understand disease and to develop countermeasures for the ongoing epidemics of Zika virus (ZIKV). Here we report a non-human primate model using a 2016 contemporary clinical isolate of ZIKV. Upon subcutaneous inoculation
Externí odkaz:
https://doaj.org/article/2620f56e14a84587b55ae54032d296f6