Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Hao Han R. Chang"'
Autor:
Jamie Anne Lugtu-Pe, Xuning Zhang, Sako Mirzaie, Hao Han R. Chang, Nour AL-Mousawi, Kuan Chen, Yongqiang Li, Anil Kane, Daniel Bar-Shalom, Xiao Yu Wu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 6, Pp 2669-2684 (2024)
Solid oral controlled release formulations feature numerous clinical advantages for drug candidates with adequate solubility and dissolution rate. However, most new chemical entities exhibit poor water solubility, and hence are exempt from such benef
Externí odkaz:
https://doaj.org/article/4955f5c4544143eda661e42ec109ad16
Autor:
Hao Han R. Chang, Kuan Chen, Jamie Anne Lugtu-Pe, Nour AL-Mousawi, Xuning Zhang, Daniel Bar-Shalom, Anil Kane, Xiao Yu Wu
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 547 (2023)
Bioavailability of weakly basic drugs may be disrupted by dramatic pH changes or unexpected pH alterations in the gastrointestinal tract. Conventional organic acids or enteric coating polymers cannot address this problem adequately because they leach
Externí odkaz:
https://doaj.org/article/a46252fc815d49d59fb058cc357c98a8
Autor:
Alireza Shalviri, Jason Li, Xiao Yu Wu, Jamie Anne Lugtu-Pe, Hao Han R. Chang, Anil Kane, Kuan Chen
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 120:116-125
Water-soluble polymers are often used as pore formers to tailor permeability of film-forming hydrophobic polymers on coated dosage forms. However, their addition to a coating formulation could significantly increase the viscosity thus making the coat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180ab8ad1fd0ec3c734354a09107ce50
https://doi.org/10.1016/j.ejpb.2017.08.014
https://doi.org/10.1016/j.ejpb.2017.08.014