Evaluation of induced pluripotent stem cell differentiation into neural progenitor cell using Raman spectra derived from extracellular vesicles in culture supernatants.

Autor: Hirai K; Center for Exploratory Research, Research and Development Group, Hitachi, Ltd., Creative Lab for Innovation in Kobe 304, 6-3-7 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Saito H; Center for Exploratory Research, Research and Development Group, Hitachi, Ltd., Creative Lab for Innovation in Kobe 304, 6-3-7 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Kato M; Center for Exploratory Research, Research and Development Group, Hitachi, Ltd., Creative Lab for Innovation in Kobe 304, 6-3-7 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Kiyama M; Center for Exploratory Research, Research and Development Group, Hitachi, Ltd., Creative Lab for Innovation in Kobe 304, 6-3-7 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Hanzawa H; Center for Exploratory Research, Research and Development Group, Hitachi, Ltd., Creative Lab for Innovation in Kobe 304, 6-3-7 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Nakane A; Regenerative and Cellular Medicine Kobe Center, Sumitomo Pharma Co., Ltd., Kobe KIMEC Center Building 5th Fl, 1-5-2 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Sekiya S; Regenerative and Cellular Medicine Office, Sumitomo Pharma Co., Ltd., Tokyo Nihonbashi Tower, 2-7-1 Nihonbashi, Tokyo 103-6012, Japan., Yoshida K; Regenerative and Cellular Medicine Office, Sumitomo Pharma Co., Ltd., Tokyo Nihonbashi Tower, 2-7-1 Nihonbashi, Tokyo 103-6012, Japan., Kishino A; Regenerative and Cellular Medicine Office, Sumitomo Pharma Co., Ltd., Tokyo Nihonbashi Tower, 2-7-1 Nihonbashi, Tokyo 103-6012, Japan., Ikeda A; Regenerative and Cellular Medicine Kobe Center, Sumitomo Pharma Co., Ltd., Kobe KIMEC Center Building 5th Fl, 1-5-2 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Kimura T; Regenerative and Cellular Medicine Office, Sumitomo Pharma Co., Ltd., Tokyo Nihonbashi Tower, 2-7-1 Nihonbashi, Tokyo 103-6012, Japan., Takahashi J; Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan., Takeda S; Center for Exploratory Research, Research and Development Group, Hitachi, Ltd., Creative Lab for Innovation in Kobe 304, 6-3-7 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan. Electronic address: shizu.takeda.me@hitachi.com.

Publikováno v: Journal of bioscience and bioengineering [J Biosci Bioeng] 2025 Jan; Vol. 139 (1), pp. 44-52. Date of Electronic Publication: 2024 Oct 16.

ASSAY DEVELOPMENT AND PILOT SCREENING AGAINST VARIOUS TYPES OF CAR-T CELLS GENERATED BY MRNA ELECTROPORATION

Autor: ishida, Y., Okuma, A., hisada, S., hanzawa, H., Takeda, S.

Publikováno v: In Cytotherapy June 2024 26(6) Supplement:S172-S172

Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α 2 δ1, a Voltage-Gated Calcium Channel Subunit.

Autor: Kozai D; Cellular and Structural Physiology Institute (CeSPI), Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan; Japan Biological Informatics Consortium, 2-4-32 Aomi, Koto-ku, Tokyo 135-0063, Japan; Advanced Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8501, Japan., Numoto N; Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8501, Japan., Nishikawa K; CeSPIA Inc., 2-1-1 Otemachi, Chiyoda-ku, Tokyo 100-0004, Japan; Joint Research Course for Advanced Biomolecular Characterization, Faculty of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan., Kamegawa A; Advanced Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8501, Japan; CeSPIA Inc., 2-1-1 Otemachi, Chiyoda-ku, Tokyo 100-0004, Japan., Kawasaki S; Daiichi Sankyo RD Novare Co., Ltd., 1-16-13 Kitakasai, Edogawa-ku, Tokyo 134-8630, Japan., Hiroaki Y; Cellular and Structural Physiology Institute (CeSPI), Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan; Japan Biological Informatics Consortium, 2-4-32 Aomi, Koto-ku, Tokyo 135-0063, Japan., Irie K; Cellular and Structural Physiology Institute (CeSPI), Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan; Department of Basic Medicinal Sciences, Graduate School of Pharmaceutical Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan., Oshima A; Cellular and Structural Physiology Institute (CeSPI), Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan; Department of Basic Medicinal Sciences, Graduate School of Pharmaceutical Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan; Institute for Glyco-core Research (iGCORE), Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan., Hanzawa H; Daiichi Sankyo RD Novare Co., Ltd., 1-16-13 Kitakasai, Edogawa-ku, Tokyo 134-8630, Japan., Shimada K; Daiichi Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan., Kitano Y; Daiichi Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan., Fujiyoshi Y; Advanced Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8501, Japan; CeSPIA Inc., 2-1-1 Otemachi, Chiyoda-ku, Tokyo 100-0004, Japan. Electronic address: yoshi.cesp@tmd.ac.jp.

Publikováno v: Journal of molecular biology [J Mol Biol] 2023 May 15; Vol. 435 (10), pp. 168049. Date of Electronic Publication: 2023 Mar 17.

Analysis of fluoroquinolone-resistance using MIC determination and homology modelling of ParC of contemporary Mycoplasma genitalium strains.

Autor: Hamasuna R; Department of Urology, Shin-Kokura Hospital, Federation of National Public Service and Affiliated Personnel Mutual Aid Association, Kitakyushu, 803-0816, Japan; Department of Urology, University of Occupational and Environmental Health, Kitakyushu, 807-8555, Japan. Electronic address: hamaryo@med.uoeh-u.ac.jp., Hanzawa H; Daiichi Sankyo RD Novare, Co. Ltd, Tokyo, 134-8630, Japan., Moritomo A; Daiichi Sankyo RD Novare, Co. Ltd, Tokyo, 134-8630, Japan., Matsumoto M; Department of Urology, University of Occupational and Environmental Health, Kitakyushu, 807-8555, Japan., Aono H; Department of Urology, University of Occupational and Environmental Health, Kitakyushu, 807-8555, Japan., Tomisaki I; Department of Urology, University of Occupational and Environmental Health, Kitakyushu, 807-8555, Japan., Akasaka T; Daiichi Sankyo, Co. Ltd, Tokyo, 103-8426, Japan., Fujimoto N; Department of Urology, University of Occupational and Environmental Health, Kitakyushu, 807-8555, Japan., Jensen JS; Statens Serum Institut, Copenhagen, DK-2300, Denmark.

Publikováno v: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy [J Infect Chemother] 2022 Mar; Vol. 28 (3), pp. 377-383. Date of Electronic Publication: 2021 Nov 24.

Analysis of extracellular vesicles as a potential index for monitoring differentiation of neural lineage cells from induced pluripotent stem cells.

Autor: Saito H; Center for Exploratory Research, Research and Development Group, Hitachi, Ltd., Kobe Center for Medical Innovation Building 201, 6-3-5 Minatojimaminamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Kato M; Center for Exploratory Research, Research and Development Group, Hitachi, Ltd., Kobe Center for Medical Innovation Building 201, 6-3-5 Minatojimaminamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Hirai K; Center for Exploratory Research, Research and Development Group, Hitachi, Ltd., Kobe Center for Medical Innovation Building 201, 6-3-5 Minatojimaminamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Kiyama M; Center for Exploratory Research, Research and Development Group, Hitachi, Ltd., Kobe Center for Medical Innovation Building 201, 6-3-5 Minatojimaminamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Ohyama K; Center for Exploratory Research, Research and Development Group, Hitachi, Ltd., Kobe Center for Medical Innovation Building 201, 6-3-5 Minatojimaminamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Hanzawa H; Center for Exploratory Research, Research and Development Group, Hitachi, Ltd., Kobe Center for Medical Innovation Building 201, 6-3-5 Minatojimaminamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Nakane A; Regenerative and Cellular Medicine Kobe Center, Sumitomo Dainippon Pharma Co., Ltd., Kobe KIMEC Center Building 5th Fl., 1-5-2 Minatojimaminamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Sekiya S; Regenerative and Cellular Medicine Kobe Center, Sumitomo Dainippon Pharma Co., Ltd., Kobe KIMEC Center Building 5th Fl., 1-5-2 Minatojimaminamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Yoshida K; Regenerative and Cellular Medicine Kobe Center, Sumitomo Dainippon Pharma Co., Ltd., Kobe KIMEC Center Building 5th Fl., 1-5-2 Minatojimaminamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Kishino A; Regenerative and Cellular Medicine Kobe Center, Sumitomo Dainippon Pharma Co., Ltd., Kobe KIMEC Center Building 5th Fl., 1-5-2 Minatojimaminamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan., Tsuchida A; Regenerative and Cellular Medicine Office, Sumitomo Dainippon Pharma Co., Ltd., 13-1 Kyobashi 1-chome, Chuo-ku, Tokyo 104-8356, Japan., Kimura T; Regenerative and Cellular Medicine Office, Sumitomo Dainippon Pharma Co., Ltd., 13-1 Kyobashi 1-chome, Chuo-ku, Tokyo 104-8356, Japan., Takahashi J; Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan., Takeda S; Center for Exploratory Research, Research and Development Group, Hitachi, Ltd., Kobe Center for Medical Innovation Building 201, 6-3-5 Minatojimaminamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan. Electronic address: shizu.takeda.me@hitachi.com.

Publikováno v: Journal of bioscience and bioengineering [J Biosci Bioeng] 2021 Oct; Vol. 132 (4), pp. 381-389. Date of Electronic Publication: 2021 Jul 18.