Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Hanxing Wan"'
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e33994- (2024)
Although the store-operated Ca2+ entry (SOCE) plays a critical role in maintaining Ca2+ homeostasis in vascular endothelial cells (VECs), its role in regulating endothelium-dependent hyperpolarization (EDH)-mediated vasorelaxation is largely unknown.
Externí odkaz:
https://doaj.org/article/06cdb16019c74fb3bb19a0d307b3cbd9
Autor:
Luyun Zhang, Wei Lu, Cheng Lu, Yanjun Guo, Xiongying Chen, Jun Chen, Feng Xu, Hanxing Wan, Hui Dong
Publikováno v:
Journal of Advanced Research, Vol 39, Iss , Pp 291-303 (2022)
Introduction: Although capsaicin has long been used as food additive and medication worldwide, its actions on gastrointestinal tract as its most delivery pathway have not been well addressed. Objectives: In the present study, we aimed to study GI act
Externí odkaz:
https://doaj.org/article/5dbf2342ec1a424991a66ee97993998d
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
AimSepsis is a life-threatening disease with high mortality worldwide. Septic females have lower severity and mortality than the males, suggesting estrogen exerts a protective action, but nothing is known about the role of vascular endothelial estrog
Externí odkaz:
https://doaj.org/article/7d3b495d31024fe2b4c1f918f6bb5fd9
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-17 (2020)
Abstract Background Although the aberrant expression and function of most Ca2+-permeable channels are known to promote gastrointestinal tumors, the association between transient receptor potential vanilloid receptor 1 (TRPV1) channels and gastric can
Externí odkaz:
https://doaj.org/article/840d87de0aba4547aa130685dff3417f
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Oral glutamine (Gln) has been widely used in gastrointestinal (GI) clinical practice, but it is unclear if Ca2+ regulates intestinal Gln transport, although both of them are essential nutrients for mammals. Chambers were used to determine Gln (25 mM)
Externí odkaz:
https://doaj.org/article/0ab648a84575468789653b3004856075
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
As little is known about the role of calcium (Ca2+) signaling mediating the small intestinal epithelial anion secretion, we aimed to study its regulatory role in secretagogue-stimulated duodenal anion secretion and the underlying molecular mechanisms
Externí odkaz:
https://doaj.org/article/e97f64e80b6f4b778eba7a9c49ac12c8
Autor:
Hanxing Wan, Rui Xie, Jiangyu Xu, Jialin He, Bo Tang, Qingqing Liu, Sumin Wang, Yanjun Guo, Xin Yang, Tobias Xiao Dong, John M. Carethers, Shiming Yang, Hui Dong
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Although purinegic signaling is important in regulating gastric physiological functions, it is currently unknown for its role in gastric cancer (GC). We demonstrate for the first time that the expression of P2Y6 receptors was markedly down-r
Externí odkaz:
https://doaj.org/article/69858d18ef004a059ef1b932cb5acecf
Publikováno v:
Biology Open, Vol 8, Iss 7 (2019)
Although K+ channels are important in mediating the driving force for colonic ion transport, their role in small intestinal transport is poorly understood. To investigate this, small intestinal short circuit currents (Isc) and HCO3− secretion were
Externí odkaz:
https://doaj.org/article/48a936ff92ac4cb59ce8699aa53c8e0c
Publikováno v:
Oncogene. 41:4169-4182
Plasma membrane Na+/Ca2+ exchanger 1 (NCX1) is a bidirectional ion transporter to operate in Ca2+ entry and exit modes, and TRPC1 is Ca2+-permeable membrane channels. Both play critical roles in maintaining cytosolic free Ca2+ ([Ca2+]cyt) homeostasis
Autor:
Cheng Lu, Hanxing Wan, Xiongying Chen, Feng Xu, Wei Lu, Yanjun Guo, Jun Chen, Hui Dong, Luyun Zhang
Publikováno v:
Journal of Advanced Research. 39:291-303
Introduction Although capsaicin has long been used as food additive and medication worldwide, its actions on gastrointestinal tract as its most delivery pathway have not been well addressed. Objectives In the present study, we aimed to study GI actio