Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Hanxiang Zeng"'
Publikováno v:
ACS Central Science, Vol 1, Iss 6, Pp 303-312 (2015)
Externí odkaz:
https://doaj.org/article/a1cd54f5f21e4602b765c0d0102ca493
Autor:
Fatemeh Sheikhi Mehrabadi, Hanxiang Zeng, Mark Johnson, Cathleen Schlesener, Zhibin Guan, Rainer Haag
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 763-772 (2015)
The success of siRNA-based therapeutics highly depends on a safe and efficient delivery of siRNA into the cytosol. In this study, we post-modified the primary amines on dendritic polyglycerolamine (dPG-NH2) with different ratios of two relevant amino
Externí odkaz:
https://doaj.org/article/c73d638d058341c79e96550a6dab79eb
Publikováno v:
ACS Central Science, Vol 1, Iss 6, Pp 303-312 (2015)
ACS Central Science
ACS Central Science
Development of safe and effective delivery vectors is a critical challenge for the application of RNA interference (RNAi)-based biotechnologies. In this study we show the rational design of a series of novel dendritic peptide bolaamphiphile vectors t
Publikováno v:
Biomacromolecules. 14:3682-3688
Nanogels have attracted much attention lately because of their many potential applications, including as nanocarriers for drug and gene delivery. Most nanogels reported previously, however, are not biodegradable, and their synthesis often requires th
Publikováno v:
Journal of the American Chemical Society. 135:4962-4965
In this study, we designed and synthesized a biodegradable dendronized polypeptide (denpol) platform for delivery of small interfering RNA (siRNA). The novel denpol architecture combines the multivalency of dendrimers and conformational flexibility o
Autor:
Hanxiang Zeng, Jens Hentschel, R. Michael van Dam, Yi-Chun Chen, Mark Lazari, Ying-Wei Yang, Zhibin Guan
Publikováno v:
J. Mater. Chem.. 22:1100-1106
We report the design and synthesis of a new perfluoropolyether-based material, which has liquid-like viscosity and can be cured into a tough, highly durable elastomer when “clicked” with selected tri-pod organic small molecules. This highly fluor
Publikováno v:
FEMS Immunology and Medical Microbiology, 58(3), 381-388. Wiley-Blackwell
Fems Immunology and Medical Microbiology
Fems Immunology and Medical Microbiology
Penicillium marneffei is the etiologic agent of a severe systemic disease in immunocompromised hosts in Southeast Asia. In the present study, a novel method, known as loop-mediated isothermal amplification (LAMP), is described for the rapid and speci
Publikováno v:
Catalysis Communications. 9:85-88
NiCl2(dppp) [dppp = 1,3-bis(diphenylphosphino)propane] shows high catalytic activity for the head-to-tail dimerization of styrene and its derivatives bearing electron-donating or electron-withdrawing groups. The dimerization proceeds with high regio-
Autor:
Zhibin Guan, Markus Hellmund, Rainer Haag, Olivia R. Cromwell, Hanxiang Zeng, Cathleen Schlesener
Publikováno v:
Biomacromolecules. 16(12)
The development of safe and effective delivery vectors is a great challenge for the medicinal application of RNA interference (RNAi). In this study, we aimed to develop new synthetic transfection agents based on dendritic polyglycercol (dPG), which h
Autor:
Rainer Haag, Fatemeh Sheikhi Mehrabadi, Hanxiang Zeng, Mark E. Johnson, Zhibin Guan, Cathleen Schlesener
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 763-772 (2015)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
The success of siRNA-based therapeutics highly depends on a safe and efficient delivery of siRNA into the cytosol. In this study, we post-modified the primary amines on dendritic polyglycerolamine (dPG-NH2) with different ratios of two relevant amino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da7ef3366c454803d18cf64f0af89fe6
http://www.beilstein-journals.org/bjoc/single/articleFullText.htm?publicId=1860-5397-11-86
http://www.beilstein-journals.org/bjoc/single/articleFullText.htm?publicId=1860-5397-11-86