Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Hanwen Wang"'
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-6 (2024)
Abstract Virtual patients and digital patients/twins are two similar concepts gaining increasing attention in health care with goals to accelerate drug development and improve patients’ survival, but with their own limitations. Although methods hav
Externí odkaz:
https://doaj.org/article/c8be30cfc1d04639866e669f18419fb1
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 6, Pp n/a-n/a (2024)
Abstract Immune checkpoint inhibitors remained the standard‐of‐care treatment for advanced non‐small cell lung cancer (NSCLC) for the past decade. In unselected patients, anti‐PD‐(L)1 monotherapy achieved an overall response rate of about 2
Externí odkaz:
https://doaj.org/article/587a54ec64914a57ababcf9a63ae499b
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 1, Pp 93-105 (2024)
Abstract Conditionally activated molecules, such as Probody therapeutics (PbTx), have recently been investigated to improve antitumoral response while reducing systemic toxicity. PbTx are engineered to be proteolytically activated by proteases that a
Externí odkaz:
https://doaj.org/article/f5f886b595a64be2aed09a568e316246
Publikováno v:
Friction, Vol 12, Iss 6, Pp 1133-1153 (2023)
Abstract Development of energy-efficient lubricants is a way to reduce energy consumption for transportation, with the tendency to design molecules that are beneficial in reducing the viscosity of synthetic oils. Oligoether esters (OEEs), as a low-vi
Externí odkaz:
https://doaj.org/article/4b998374d45141e988c6ba59bdc49cbf
Autor:
Linzhuang Liu, Qinghua Hou, Baorong Chen, Xiyi Lai, Hanwen Wang, Haozhen Liu, Liusheng Wu, Sheng Liu, Kelin Luo, Jixian Liu
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-16 (2023)
Abstract Objective Oxidative stress is associated with the occurrence and development of lung cancer. However, the specific association between lung cancer and oxidative stress is unclear. This study aimed to investigate the role of oxidative stress
Externí odkaz:
https://doaj.org/article/9a62a6bdf0f040dfb4cd6ce4663a332d
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-14 (2023)
Abstract Generating realistic virtual patients from a limited amount of patient data is one of the major challenges for quantitative systems pharmacology modeling in immuno-oncology. Quantitative systems pharmacology (QSP) is a mathematical modeling
Externí odkaz:
https://doaj.org/article/eb7a0620f4954e65a3aadd7ab5c5b2e4
Autor:
Kaining Yang, Xiang Gao, Yaning Wang, Tongyao Zhang, Yuchen Gao, Xin Lu, Shihao Zhang, Jianpeng Liu, Pingfan Gu, Zhaoping Luo, Runjie Zheng, Shimin Cao, Hanwen Wang, Xingdan Sun, Kenji Watanabe, Takashi Taniguchi, Xiuyan Li, Jing Zhang, Xi Dai, Jian-Hao Chen, Yu Ye, Zheng Han
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract The realization of graphene gapped states with large on/off ratios over wide doping ranges remains challenging. Here, we investigate heterostructures based on Bernal-stacked bilayer graphene (BLG) atop few-layered CrOCl, exhibiting an over-1
Externí odkaz:
https://doaj.org/article/1746abe656db439894f13e3c00148316
Autor:
Hanwen Wang, Liwei Zhang, Manguang Gan, Xuebin Su, Yan Wang, Quan Xue, Kaiyuan Mei, Xiaojuan Fu
Publikováno v:
Applied Sciences, Vol 14, Iss 2, p 728 (2024)
In the present study, an immersion experiment was carried out to examine how N80 steel corrodes when exposed to formation water containing dissolved CO2 and supercritical CO2 (Sc-CO2) along with water vapor. We employed electrochemical and surface an
Externí odkaz:
https://doaj.org/article/a3e76a984836410cad2a656a222f45d0
Autor:
Samira Anbari, Hanwen Wang, Yu Zhang, Jun Wang, Minu Pilvankar, Masoud Nickaeen, Steven Hansel, Aleksander S. Popel
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Although immune checkpoint blockade therapies have shown evidence of clinical effectiveness in many types of cancer, the outcome of clinical trials shows that very few patients with colorectal cancer benefit from treatments with checkpoint inhibitors
Externí odkaz:
https://doaj.org/article/74c52bdd422e418388ad70df4d0117e6
Autor:
Kang Lai, Sailong Ju, Hongen Zhu, Hanwen Wang, Hongjian Wu, Bingjie Yang, Enrui Zhang, Ming Yang, Fangsen Li, Shengtao Cui, Xiaohui Deng, Zheng Han, Mengjian Zhu, Jiayu Dai
Publikováno v:
Communications Physics, Vol 5, Iss 1, Pp 1-7 (2022)
Conventionally, the in-plane electronic band structure anisotropy originates from the low crystallographic symmetry in the layered material. Here, using angle-resolved photoemission spectroscopy and density functional theory the authors report that t
Externí odkaz:
https://doaj.org/article/71a761a59e434988a97e46b788415bad