Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hanwen Bai"'
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
The identification of cancer subtypes plays a very important role in the field of medicine. Accurate identification of cancer subtypes is helpful for both cancer treatment and prognosis Currently, most methods for cancer subtype identification are ba
Externí odkaz:
https://doaj.org/article/4f014307b12741179c935d5f6d0a9626
Autor:
Akdes Serin Harmancı, Mark W. Youngblood, Victoria E. Clark, Süleyman Coşkun, Octavian Henegariu, Daniel Duran, E. Zeynep Erson-Omay, Leon D. Kaulen, Tong Ihn Lee, Brian J. Abraham, Matthias Simon, Boris Krischek, Marco Timmer, Roland Goldbrunner, S. Bülent Omay, Jacob Baranoski, Burçin Baran, Geneive Carrión-Grant, Hanwen Bai, Ketu Mishra-Gorur, Johannes Schramm, Jennifer Moliterno, Alexander O. Vortmeyer, Kaya Bilgüvar, Katsuhito Yasuno, Richard A. Young, Murat Günel
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Meningiomas are mostly benign brain tumours with the potential for becoming atypical or malignant. Here, the authors show that primary atypical meningiomas are epigenetically and genetically distinct from benign and progressed tumours, highlighting p
Externí odkaz:
https://doaj.org/article/d27c23c5f6b847e4a5ce5684ebe1b356
Autor:
Akdes Serin Harmancı, Mark W. Youngblood, Victoria E. Clark, Süleyman Coşkun, Octavian Henegariu, Daniel Duran, E. Zeynep Erson-Omay, Leon D. Kaulen, Tong Ihn Lee, Brian J. Abraham, Matthias Simon, Boris Krischek, Marco Timmer, Roland Goldbrunner, S. Bülent Omay, Jacob Baranoski, Burçin Baran, Geneive Carrión-Grant, Hanwen Bai, Ketu Mishra-Gorur, Johannes Schramm, Jennifer Moliterno, Alexander O. Vortmeyer, Kaya Bilgüvar, Katsuhito Yasuno, Richard A. Young, Murat Günel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications 8: Article number: 14433 (2017) Published online 14 February 2017; Updated 20 April 2018 In this Article, a subset of the H3K27ac ChIP-seq data (15 benign meningiomas and 2 dura samples (Sample IDs: MN-297, MN-288, MN-292, MN-16
Externí odkaz:
https://doaj.org/article/6f63b2d4e7c84e9b9c9b5b660f84a4ca
Autor:
Hanna Rennert, Brian D. Robinson, Adrian Y. Tan, Jon D. Blumenfeld, Ines Chicos, Steven P. Salvatore, Hanwen Bai, Sandip Kapur, Stavros Giannakopoulos, Lior Rennert, Martin R. Prince, Zhengmao Zhang, Irina Barash, Alber Michaeel, Andrew B. Ramnauth, Karen Larbi, Genyan Liu, Stuart W. Hughes
Publikováno v:
J Am Soc Nephrol
Background: Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by the development of multiple cysts in the kidneys. It is often caused by pathogenic mutations in PKD1 and PKD2 genes that encode polycystin protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::534d73252ff87a211cfa17ae0df7cae3
https://doi.org/10.1681/asn.2021050690
https://doi.org/10.1681/asn.2021050690
Autor:
Richard A. Young, Murat Gunel, Katsuhito Yasuno, Geneive Carrión-Grant, Burçin Baran, Victoria E. Clark, Daniel Duran, Boris Krischek, Roland Goldbrunner, Marco Timmer, Ketu Mishra-Gorur, Süleyman Coşkun, Matthias Simon, Octavian Henegariu, Hanwen Bai, Jennifer Moliterno, E. Zeynep Erson-Omay, Johannes Schramm, Brian J. Abraham, Akdes Serin Harmanci, Leon D. Kaulen, Alexander O. Vortmeyer, S. Bulent Omay, Jacob F Baranoski, Tong Ihn Lee, Kaya Bilguvar, Mark W. Youngblood
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications 8: Article number: 14433 (2017) Published online 14 February 2017; Updated 20 April 2018 In this Article, a subset of the H3K27ac ChIP-seq data (15 benign meningiomas and 2 dura samples (Sample IDs: MN-297, MN-288, MN-292, MN-16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef98952dac99961283fb1862ff13e6b
https://doi.org/10.1038/ncomms16215
https://doi.org/10.1038/ncomms16215
Publikováno v:
American Journal of Botany. 100:175-182
Premise of the study Lateral roots, responsible for water and nutrient uptake, maintain nonvertical angles throughout development. Soil phosphate is one limiting nutrient for plant growth that is known to induce changes to root system architecture, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ad5a6fbf2ba5138170a724a9d60f015
https://doi.org/10.3732/ajb.1200285
https://doi.org/10.3732/ajb.1200285
Autor:
Henk M. De Feyter, Nathaniel D. Robinson, Parker L. Sulkowski, Murat Gunel, Gregory A. Breuer, Denise C. Hegan, Susan E. Scanlon, Ketu Mishra-Gorur, Ranjit S. Bindra, Karin Purshouse, Peter M. Glazer, Nathan R. Fons, Yanfeng Liu, Ranjini K. Sundaram, Hanwen Bai, Christopher D. Corso, Stephanie Halene, Maureen Kachman, Robin A. de Graaf, Yulia V. Surovtseva, Yuanbin Song
Publikováno v:
Science translational medicine. 9(375)
2-Hydroxyglutarate (2HG) exists as two enantiomers, (R)-2HG and (S)-2HG, and both are implicated in tumor progression via their inhibitory effects on α-ketoglutarate (αKG)-dependent dioxygenases. The former is an oncometabolite that is induced by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129e421a49698f48360c1f06ba8e8f38
https://pubmed.ncbi.nlm.nih.gov/28148839
https://pubmed.ncbi.nlm.nih.gov/28148839
Autor:
Geneive Carrión-Grant, Roland Goldbrunner, Brian J. Abraham, Akdes Serin Harmanci, Octavian Henegariu, Daniel Duran, Johanna Goldmann, Tong Ihn Lee, Matthias Simon, Katsuhito Yasuno, Hanwen Bai, Alexander O. Vortmeyer, Jacob F Baranoski, Ketu Mishra-Gorur, Joseph M. Piepmeier, Victoria E. Clark, Kaya Bilguvar, Abraham S. Weintraub, A. Gulhan Ercan-Sencicek, Boris Krischek, Mark W. Youngblood, Richard A. Young, Murat Gunel, Denes Hnisz, E. Zeynep Erson-Omay, Johannes Schramm, Jennifer Moliterno Günel
RNA polymerase II mediates the transcription of all protein-coding genes in eukaryotic cells, a process that is fundamental to life. Genomic mutations altering this enzyme have not previously been linked to any pathology in humans, which is a testame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba62a876c1e0f9544a483bc677f700b2
https://europepmc.org/articles/PMC5114141/
https://europepmc.org/articles/PMC5114141/
Autor:
Şirin Yüksel, I. Melis Durası, Sevin Turcan, Murat Gunel, Jason T. Huse, M. Necmettin Pamir, Cemaliye B Akyerli, E. Paolo Nanni, M. Cengiz Yakıcıer, Manu Gupta, Adrienne M. Flanagan, Nathalie Selevsek, M. Aydın Sav, Özge Can, Jonas Grossmann, O. Uğur Sezerman, Aysel Ozpinar, William Lee, E. Zeynep Erson-Omay, Yavuz Oktay, Hanwen Bai, Ege Ülgen, Yigit Erdemgil, Koray Özduman, Octavian Henegariu
Publikováno v:
Scientific Reports
Scientific Reports, 6
Scientific Reports, 6
The single nucleotide polymorphism rs55705857, located in a non-coding but evolutionarily conserved region at 8q24.21, is strongly associated with IDH-mutant glioma development and was suggested to be a causal variant. However, the molecular mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb794f575ff85fa2cf1a470ace5dc7a
The use of next-generation sequencing technologies has transformed our understanding of the molecular pathways driving the formation of central nervous system tumors. Tumor classification, once based primarily on observable histopathologic findings,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5ab0b1d147448577ac42ec796639104
https://doi.org/10.1016/b978-0-12-800105-9.00040-8
https://doi.org/10.1016/b978-0-12-800105-9.00040-8